Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Sarah E DeMarco"'
Autor:
Taixiang Saur, Sarah E DeMarco, Angelica Ortiz, Gregory R Sliwoski, Limin Hao, Xin Wang, Bruce M Cohen, Edgar A Buttner
Publikováno v:
PLoS Genetics, Vol 9, Iss 2, p e1003313 (2013)
We report a genome-wide RNA interference (RNAi) screen for Suppressors of Clozapine-induced Larval Arrest (scla genes) in Caenorhabditis elegans, the first genetic suppressor screen for antipsychotic drug (APD) targets in an animal. The screen identi
Externí odkaz:
https://doaj.org/article/50de190b421c4e0fbd75db1a96880fda
Autor:
Zhihua Xie, Rakesh Karmacharya, Edgar A. Buttner, Gregory M. Miller, Miriam Y. Lundy, Angelica Ortiz, Xin Wang, Sarah E. DeMarco, Bruce M. Cohen, Spencer K. Lynn
Publikováno v:
Brain Research. 1393:91-99
Clozapine is an antipsychotic medication with superior efficacy in treatment-refractory schizophrenia. The molecular basis of clozapine’s therapeutic profile is not well understood. We studied behavioral effects of clozapine in Caenorhabditis elega
Autor:
Angelica Ortiz, Sarah E. DeMarco, Xin Wang, Gregory Sliwoski, Bruce M. Cohen, Taixiang Saur, Edgar A. Buttner, Limin Hao
Publikováno v:
PLoS Genetics
PLoS Genetics, Vol 9, Iss 2, p e1003313 (2013)
PLoS Genetics, Vol 9, Iss 2, p e1003313 (2013)
We report a genome-wide RNA interference (RNAi) screen for Suppressors of Clozapine-induced Larval Arrest (scla genes) in Caenorhabditis elegans, the first genetic suppressor screen for antipsychotic drug (APD) targets in an animal. The screen identi