Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Sarah E Brennan-Laun"'
Autor:
Dig B Mahat, Sarah E Brennan-Laun, Elizabeth J Fialcowitz-White, Aparna Kishor, Christina R Ross, Tatyana Pozharskaya, J David Rawn, Perry J Blackshear, Bret A Hassel, Gerald M Wilson
Publikováno v:
PLoS ONE, Vol 7, Iss 3, p e33194 (2012)
The serine/threonine kinase Pim-1 directs selected signaling events that promote cell growth and survival and is overexpressed in diverse human cancers. Pim-1 expression is tightly controlled through multiple mechanisms, including regulation of mRNA
Externí odkaz:
https://doaj.org/article/61aaa13dc15c4d88a7caee877e2788a9
RNase-L Control of Cellular mRNAs: Roles in Biologic Functions and Mechanisms of Substrate Targeting
Publikováno v:
Journal of Interferon & Cytokine Research. 34:275-288
RNase-L is a mediator of type 1 interferon-induced antiviral activity that has diverse and critical cellular roles, including the regulation of cell proliferation, differentiation, senescence and apoptosis, tumorigenesis, and the control of the innat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c8abcaee6fd52f70e0b841131e731409
https://doi.org/10.1089/jir.2013.0147
https://doi.org/10.1089/jir.2013.0147
Autor:
Heather J. Ezelle, Bret A. Hassel, Xiaoling Li, Perry J. Blackshear, Gerald M. Wilson, Sarah E. Brennan-Laun, Thiagarajan Venkataraman
The cellular response to mitogens is tightly regulated via transcriptional and post-transcriptional mechanisms to rapidly induce genes that promote proliferation and efficiently attenuate their expression to prevent malignant growth. RNase L is an en
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7264a0375713e7521050aa5fbbf7b051
https://europepmc.org/articles/PMC4246114/
https://europepmc.org/articles/PMC4246114/
Autor:
Irina Polyakova, Arindam Chakrabarti, Robert H. Silverman, Jean-Pierre Raufman, Heather J. Ezelle, Bret A. Hassel, Tiha M. Long, Sarah E. Brennan-Laun
Background The endoribonuclease RNase-L is a type-I interferon (IFN)-regulated component of the innate immune response that functions in antiviral, antibacterial, and antiproliferative activities. RNase-L produces RNA agonists of RIG-I-like receptors
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f18564b6070a69199a968a58cfbe93a3
https://europepmc.org/articles/PMC3703736/
https://europepmc.org/articles/PMC3703736/
Publikováno v:
Ageing research reviews. 11(4)
Cancer and senescence are both complex transformative processes that dramatically alter many features of cell physiology and their interactions with surrounding tissues. Developing the wide range of cellular features characteristic of these condition
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0f24a577b60f2293eb20655e353bbe6e
https://pubmed.ncbi.nlm.nih.gov/22387927
https://pubmed.ncbi.nlm.nih.gov/22387927
Autor:
Irina Polyakova, Robert H. Silverman, Bret A. Hassel, Tiha M. Long, Heather J. Ezelle, Jean-Pierre Raufman, Sarah E. Brennan-Laun, Arindam Chakrabarti
Publikováno v:
Cancer Research. 73:2863-2863
The endoribonuclease RNase-L is a Type-I interferon (IFN)-regulated component of the innate immune response that functions in antiviral and antibacterial activities. Here we identify a protective role for RNase-L in the inflammatory response to gastr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f36ee318903a2ee5bfb5a93c308a10c6
https://doi.org/10.1158/1538-7445.am2013-2863
https://doi.org/10.1158/1538-7445.am2013-2863
Publikováno v:
Cancer Research. 73:3197-3197
RNase-L is an endoribonuclease that functions in a range of important physiologic activities including the innate immune response and control of cell proliferation and is dysregulated in pathologic conditions including cancer. RNase-L is tightly regu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::80b207502ec0056b8c856ac17fa8846d
https://doi.org/10.1158/1538-7445.am2013-3197
https://doi.org/10.1158/1538-7445.am2013-3197