Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Sarah E, Ongley"'
Autor:
Simon A. Hardwick, Wendy Y. Chen, Ted Wong, Bindu S. Kanakamedala, Ira W. Deveson, Sarah E. Ongley, Nadia S. Santini, Esteban Marcellin, Martin A. Smith, Lars K. Nielsen, Catherine E. Lovelock, Brett A. Neilan, Tim R. Mercer
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-10 (2018)
Complex microbial communities pose a challenge to metagenomic analysis. Here the authors develop ‘sequins’, internal DNA standards that represent a synthetic community of artificial genomes.
Externí odkaz:
https://doaj.org/article/db9f1c1f4bb54a1cb1792bb0e5f72ff5
Autor:
Brett A. Neilan, Russel Pickford, Sarah E. Ongley, Elke Dittmann, Jan-Christoph Kehr, Angela H. Soeriyadi
Publikováno v:
ChemBioChem. 23
Indolactam alkaloids are activators of protein kinase C (PKC) and are of pharmacological interest for the treatment of pathologies involving PKC dysregulation. The marine cyanobacterial nonribosomal peptide synthetase (NRPS) pathway for lyngbyatoxin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e0a37949b99231cd4410fa30f26d6765
https://doi.org/10.1002/cbic.202100574
https://doi.org/10.1002/cbic.202100574
Autor:
Alescia Cullen, Rabia Mazmouz, Sarah E. Ongley, Leanne A. Pearson, Brett A. Neilan, Tianzhe Liu, Angela H. Soeriyadi
Publikováno v:
Natural Product Reports. 36:1117-1136
Covering: up to 2018 Marine and freshwater cyanobacteria produce a variety of toxic compounds that pose a threat to the health of humans, livestock and natural ecosystems world-wide. Significant research efforts have been directed towards understandi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e9afed3aaaad96929027efe04e122b6e
https://doi.org/10.1039/c8np00063h
https://doi.org/10.1039/c8np00063h
Autor:
Tianzhe Liu, Brett A. Neilan, Jason N. Woodhouse, Rocky Chau, Rabia Mazmouz, Sarah E. Ongley, Russell Pickford
Publikováno v:
ACS Chemical Biology. 12:2021-2029
Microcystins are globally the most commonly occurring freshwater cyanotoxins, causing acute poisoning and chronically inducing hepatocellular carcinoma. However, the detection and toxicological study of microcystins is hampered by the limited availab
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4be379432da40ac2014f4bde85fe99a4
https://doi.org/10.1021/acschembio.7b00181
https://doi.org/10.1021/acschembio.7b00181
Autor:
Brett A. Neilan, Leanne A. Pearson, Elke Dittmann, Sarah E. Ongley, Paul M. D'Agostino, Rabia Mazmouz
Publikováno v:
Harmful Algae. 54:98-111
The production of toxic metabolites by cyanobacterial blooms represents a significant threat to the health of humans and ecosystems worldwide. Here we summarize the current state of the knowledge regarding the genetics, biosynthesis and regulation of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f5a134e107cb111072255f25905f4a08
https://doi.org/10.1016/j.hal.2015.11.002
https://doi.org/10.1016/j.hal.2015.11.002
Publikováno v:
Journal of Applied Phycology. 28:2793-2803
The genome of the model cyanobacterium Synechocystis sp. PCC6803 contains 28 genes encoding multidrug efflux transporters, including only two transporters from the multidrug and toxic compound extrusion (MATE) family (Slr0896 and Slr1543, NorM- and D
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1b54d2f87c1619bff34c5f85f406b7ad
https://doi.org/10.1007/s10811-016-0816-5
https://doi.org/10.1007/s10811-016-0816-5
Autor:
Jason N. Woodhouse, Paul M. D'Agostino, A. Katharina Makower, Anna C. Y. Yeung, Brett A. Neilan, Melinda L. Micallef, Michelle C. Moffitt, Sarah E. Ongley
Publikováno v:
Environmental Microbiology Reports. 8:3-13
A common misconception persists that the genomes of toxic and non-toxic cyanobacterial strains are largely conserved with the exception of the presence or absence of the genes responsible for toxin production. Implementation of -omics era technologie
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5f6f09fce26a62412a172a27289228b6
https://doi.org/10.1111/1758-2229.12366
https://doi.org/10.1111/1758-2229.12366
Publikováno v:
Blue Biotechnology ISBN: 9783527801718
Blue Biotechnology
Blue Biotechnology
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::22ba45080489e592532f0154170f16ec
https://doi.org/10.1002/9783527801718.ch17
https://doi.org/10.1002/9783527801718.ch17
Autor:
Nadia S. Santini, Lars K. Nielsen, Tim R. Mercer, Ira W. Deveson, Wendy Y. Chen, Martin A. Smith, Brett A. Neilan, Bindu S. Kanakamedala, Esteban Marcellin, Sarah E. Ongley, Ted Wong, Simon A. Hardwick, Catherine E. Lovelock
Publikováno v:
Nature Communications
Nature Communications, Vol 9, Iss 1, Pp 1-10 (2018)
Nature Communications, Vol 9, Iss 1, Pp 1-10 (2018)
The complexity of microbial communities, combined with technical biases in next-generation sequencing, pose a challenge to metagenomic analysis. Here, we develop a set of internal DNA standards, termed “sequins” (sequencing spike-ins), that toget
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d2bdaf82a62121fb99477c059107a42e
http://europepmc.org/articles/PMC6078961
http://europepmc.org/articles/PMC6078961
Publikováno v:
Environmental Microbiology. 18:427-438
Saxitoxins (STX), neurotoxic alkaloids, fall under the umbrella of paralytic shellfish toxins produced by marine dinoflagellates and freshwater cyanobacteria. The genes responsible for the production of STX have been proposed, but factors that influe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7e21e0faea5ee69976f6f0a3349d28c9
https://doi.org/10.1111/1462-2920.13048
https://doi.org/10.1111/1462-2920.13048