Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Sarah E, Ochmann"'
Publikováno v:
Analytical Chemistry. 94:2633-2640
Charges in lipid head groups generate electrical surface potentials at cell membranes, and changes in their composition are involved in various signaling pathways, such as T-cell activation or apoptosis. Here, we present a DNA origami-based sensor fo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::87ffa1e019d1c5428ea232e9775261f8
https://doi.org/10.1021/acs.analchem.1c05092
https://doi.org/10.1021/acs.analchem.1c05092
Autor:
Tim Schröder, Johann Bohlen, Sarah E. Ochmann, Patrick Schüler, Stefan Krause, Don C. Lamb, Philip Tinnefeld
Publikováno v:
Proceedings of the National Academy of Sciences. 120
Fluorescence correlation spectroscopy is a versatile tool for studying fast conformational changes of biomolecules especially when combined with Förster resonance energy transfer (FRET). Despite the many methods available for identifying structural
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::382c296ab4b5da042c06751321cdd081
https://doi.org/10.1073/pnas.2211896120
https://doi.org/10.1073/pnas.2211896120
Autor:
Sarah E. Ochmann, Barbara Saccà, Himanshu Joshi, Ulrich F. Keyser, Pierre Stegemann, Henri G. Franquelim, E. Bueber, Philip Tinnefeld, Aleksei Aksimentiev
Publikováno v:
Nano letters. 21(20)
Signal transmission in neurons goes along with changes in the transmembrane potential. To report them, different approaches including optical voltage-sensing dyes and genetically encoded voltage indicators have evolved. Here, we present a DNA nanotec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7be56a3ef16e20e0473166fb523ffebe
https://pubmed.ncbi.nlm.nih.gov/34662130
https://pubmed.ncbi.nlm.nih.gov/34662130
Autor:
Aydogan Ozcan, Kateryna Trofymchuk, Sarah E. Ochmann, Viktorija Glembockyte, Hakan Inan, Cindy Close, Philip Tinnefeld, Birka Lalkens, Carolin Vietz, Guillermo P. Acuna, Qingshan Wei, Lennart Grabenhorst
Publikováno v:
Scopus-Elsevier
In recent years, DNA nanotechnology has matured to enable robust production of complex nanostructures and hybrid materials. We have combined DNA nanotechnology with sensitive optical detection to create functional single-molecule devices that enable
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::34b0ed987d9f33d655c4e76799cf36cb
https://doi.org/10.1364/oma.2019.aw5e.5
https://doi.org/10.1364/oma.2019.aw5e.5
Autor:
Elisa A, Hemmig, Clare, Fitzgerald, Christopher, Maffeo, Lisa, Hecker, Sarah E, Ochmann, Aleksei, Aksimentiev, Philip, Tinnefeld, Ulrich F, Keyser
Publikováno v:
Nano Letters
We explore the potential of DNA nanotechnology for developing novel optical voltage sensing nanodevices that convert a local change of electric potential into optical signals. As a proof-of-concept of the sensing mechanism, we assembled voltage respo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::9e3c44dc165bf8c344ce3ff7a94777cb
https://pubmed.ncbi.nlm.nih.gov/29430924
https://pubmed.ncbi.nlm.nih.gov/29430924
Autor:
Philip Tinnefeld, Kateryna Trofymchuk, Birka Lalkens, Carolin Vietz, Sarah E. Ochmann, Guillermo P. Acuna
Publikováno v:
Analytical chemistry. 89(23)
Because of the limited signal-to-background ratio, molecular diagnostics requires molecular amplification of the target molecules or molecular signal amplification after target recognition. For direct molecular detection, we demonstrate a purely phys
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a4dedb1bde3721a4b72d6fcfa0c95878
https://pubmed.ncbi.nlm.nih.gov/29144729
https://pubmed.ncbi.nlm.nih.gov/29144729
Chm7 and Heh1 collaborate to link nuclear pore complex quality control with nuclear envelope sealing
The integrity of the nuclear envelope barrier relies on membrane remodeling by the ESCRTs, which seal nuclear envelope holes and contribute to the quality control of nuclear pore complexes (NPCs); whether these processes are mechanistically related r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::096b56fb543e6fae9c656f0cc35bfb73
https://europepmc.org/articles/PMC5109239/
https://europepmc.org/articles/PMC5109239/
Mechanisms that ensure the integrity of the nuclear envelope rely on membrane remodeling proteins like the ESCRTs and the AAA ATPase Vps4, which help seal the nuclear envelope at the end of mitosis and prevent the formation of defective nuclear pore
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1b1170710f067793eb61697fdb37f11f
https://doi.org/10.1101/049148
https://doi.org/10.1101/049148