Zobrazeno 1 - 10
of 354
pro vyhledávání: '"Sarah E, O'Connor"'
Autor:
Lovely Mae F. Lawas, Mohamed O. Kamileen, C. Robin Buell, Sarah E. O'Connor, Courtney P. Leisner
Publikováno v:
Plant Direct, Vol 7, Iss 7, Pp n/a-n/a (2023)
Abstract Blueberries (Vaccinium spp.) are well known for their nutritional quality, and recent work has shown that Vaccinium spp. also produce iridoids, which are specialized metabolites with potent health‐promoting benefits. The iridoid glycoside
Externí odkaz:
https://doaj.org/article/da28811859e342ca8647f37bd810e14e
Autor:
Quentin M. Dudley, Seohyun Jo, Delia Ayled Serna Guerrero, Monika Chhetry, Mark A. Smedley, Wendy A. Harwood, Nathaniel H. Sherden, Sarah E. O’Connor, Lorenzo Caputi, Nicola J. Patron
Publikováno v:
Communications Biology, Vol 5, Iss 1, Pp 1-12 (2022)
The biosynthesis of strictosidine, a key intermediate of monoterpene indole alkaloids, was successfully reconstructed in Nicotiana benthamiana, demonstrating the potential of Nicotiana benthamiana as a bioproduction chassis for small molecules.
Externí odkaz:
https://doaj.org/article/e29c0ea27a5d47e78bf7530e3ad04987
Autor:
Néstor J. Hernández Lozada, Benke Hong, Joshua C. Wood, Lorenzo Caputi, Jérôme Basquin, Ling Chuang, Maritta Kunert, Carlos E. Rodríguez López, Chloe Langley, Dongyan Zhao, C. Robin Buell, Benjamin R. Lichman, Sarah E. O’Connor
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-13 (2022)
Iridoid compounds are an important class of natural products. Here, the authors report on the discovery and engineering of nepetalactol-related short chain reductases and their application for the biosynthesis of nepetalactol or nepetalactone stereoi
Externí odkaz:
https://doaj.org/article/25ab1b4b3b3b4dc29163150181a67ada
Publikováno v:
Frontiers in Plant Science, Vol 13 (2022)
Plants produce a wide variety of pharmacologically active molecules classified as natural products. Derivatization of these natural products can modulate or improve the bioactivity of the parent compound. Unfortunately, chemical derivatization of nat
Externí odkaz:
https://doaj.org/article/bc725de3968b46d0bea1863ee08f2663
Autor:
Sarah E. O’Connor
Publikováno v:
ACS Central Science, Vol 7, Iss 2, Pp 225-227 (2021)
Externí odkaz:
https://doaj.org/article/057394f27df34449aa4f3c46ad1ff1fa
Autor:
Néstor J. Hernández Lozada, Benke Hong, Joshua C. Wood, Lorenzo Caputi, Jérôme Basquin, Ling Chuang, Maritta Kunert, Carlos E. Rodríguez López, Chloe Langley, Dongyan Zhao, C. Robin Buell, Benjamin R. Lichman, Sarah E. O’Connor
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-1 (2022)
Externí odkaz:
https://doaj.org/article/c5e7fa52e8da4700ba411104aeca0fc9
Autor:
Julia Brose, Kin H Lau, Thu Thuy Thi Dang, John P Hamilton, Lívia do Vale Martins, Britta Hamberger, Bjoern Hamberger, Jiming Jiang, Sarah E O’Connor, C Robin Buell
Publikováno v:
G3: Genes, Genomes, Genetics, Vol 11, Iss 4 (2021)
Abstract Mitragyna speciosaM. speciosaM. speciosa
Externí odkaz:
https://doaj.org/article/136869ddf8f641968f3e549f534744f9
Autor:
Larissa C. Laforest, Michelle A. Kuntz, Siva Rama Raju Kanumuri, Sushobhan Mukhopadhyay, Abhisheak Sharma, Sarah E. O’Connor, Christopher R. McCurdy, Satya Swathi Nadakuduti
Publikováno v:
Journal of Natural Products. 86:1042-1052
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a4d4428f01b07d8d5f2d5f9e00ead0f6
https://doi.org/10.1021/acs.jnatprod.3c00092
https://doi.org/10.1021/acs.jnatprod.3c00092
Autor:
Carsten Schotte, Yindi Jiang, Dagny Grzech, Thu-Thuy T. Dang, Larissa C. Laforest, Francisco León, Marco Mottinelli, Satya Swathi Nadakuduti, Christopher R. McCurdy, Sarah E. O’Connor
Publikováno v:
Journal of the American Chemical Society
Mitragyna speciosa(“Kratom”) is used as a natural remedy for pain and management of opioid dependence. The pharmacological properties of Kratom have been linked to a complex mixture of monoterpene indole alkaloids, most notably mitragynine. Here,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4b3d2974dfda1ffe4598f63db485a349
https://doi.org/10.1021/jacs.2c13644
https://doi.org/10.1021/jacs.2c13644
Autor:
Katharine Davis, Danai S. Gkotsi, Duncan R. M. Smith, Rebecca J. M. Goss, Lorenzo Caputi, Sarah E. O’Connor
Publikováno v:
Frontiers in Plant Science, Vol 11 (2020)
Plant secondary metabolites have applications for the food, biofuel, and pharmaceutical industries. Recent advances in pathway elucidation and host expression systems now allow metabolic engineering of plant metabolic pathways to produce “new-to-na
Externí odkaz:
https://doaj.org/article/e329153a04ac41bab6b390ffbe57ce64