Transmission of the Potential Pathogen Atypical Enteropathogenic Escherichia coli by Fecal Microbiota Transplant

Autor: Sarah E. Kralicek, Celeste Jenkins, Jessica R. Allegretti, James D. Lewis, Majdi Osman, Gail A. Hecht

Publikováno v: Gastroenterology.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::3dc07c92ea5083f9d44350bae445437d
https://doi.org/10.1053/j.gastro.2023.03.222

EPEC NleH1 is significantly more effective in reversing colitis and reducing mortality than NleH2 via differential effects on host signaling pathways

Autor: Gail Hecht, Ki Jong Rhee, Rocio Tapia, Sarah E. Kralicek, Mai Nguyen

Publikováno v: Laboratory investigation; a journal of technical methods and pathology

Enteropathogenic Escherichia coli (EPEC) is a foodborne pathogen that uses a type III secretion system to translocate effector molecules into host intestinal epithelial cells (IECs) subverting several host cell processes and signaling cascades. Inter

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a022a260b9894c5cdb53b5ce532e40eb
http://europepmc.org/articles/PMC5920738

Enteropathogenic Escherichia coli (EPEC) Recruitment of PAR Polarity Protein Atypical PKCζ to Pedestals and Cell–Cell Contacts Precedes Disruption of Tight Junctions in Intestinal Epithelial Cells

Autor: Gail Hecht, Rocio Tapia, Sarah E. Kralicek

Publikováno v: International Journal of Molecular Sciences, Vol 21, Iss 2, p 527 (2020)
International Journal of Molecular Sciences
Volume 21
Issue 2

Enteropathogenic Escherichia coli (EPEC) uses a type three secretion system to inject effector proteins into host intestinal epithelial cells, causing diarrhea. EPEC induces the formation of pedestals underlying attached bacteria, disrupts tight junc

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c6b39cc263ae4cc8984c57cfd132b4c5
https://www.mdpi.com/1422-0067/21/2/527

Quantitative analysis and virulence phenotypes of atypical enteropathogenic Escherichia coli (EPEC) acquired from diarrheal stool samples from a Midwest US hospital

Autor: Gail Hecht, Maximillian J. Carlino, SA Santiago, AT Harrington, Sarah E. Kralicek, Lalitha Sitaraman

Publikováno v: Gut Microbes
article-version (VoR) Version of Record
Gut Microbes, Vol 12, Iss 1 (2020)

Infectious diarrhea causes approximately 179 million illnesses annually in the US. Multiplex PCR assays for enteric pathogens detect enteropathogenic Escherichia coli (EPEC) in 12–29% of diarrheal stool samples from all age groups in developed nati

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b4a41e46583a9b70176dbda7b1b51033
https://doi.org/10.1080/19490976.2020.1824562

Sperm Flagellar 1 Binds Actin in Intestinal Epithelial Cells and Contributes to Formation of Filopodia and Lamellipodia

Autor: Gail Hecht, Maximillian J. Carlino, Sarah E. Kralicek, Rocio Tapia, Umesh C. Karandikar, Eloy Andrés Pérez-Yépez, Mary K. Estes

Publikováno v: Gastroenterology

Background & Aims Sperm flagellar 1 (also called CLAMP) is a microtubule-associated protein that regulates microtubule dynamics and planar cell polarity in multi-ciliated cells. We investigated the localization and function of sperm flagellar 1, or C

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8b862036e834fb94b4f6d57bde46cae6
https://pubmed.ncbi.nlm.nih.gov/31473225