Zobrazeno 1 - 10
of 169
pro vyhledávání: '"Sarah E, Church"'
Autor:
Jiwoon Park, Eliah G. Overbey, S. Anand Narayanan, JangKeun Kim, Braden T. Tierney, Namita Damle, Deena Najjar, Krista A. Ryon, Jacqueline Proszynski, Ashley Kleinman, Jeremy Wain Hirschberg, Matthew MacKay, Evan E. Afshin, Richard Granstein, Justin Gurvitch, Briana M. Hudson, Aric Rininger, Sean Mullane, Sarah E. Church, Cem Meydan, George Church, Afshin Beheshti, Jaime Mateus, Christopher E. Mason
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-14 (2024)
Abstract Spaceflight can change metabolic, immunological, and biological homeostasis and cause skin rashes and irritation, yet the molecular basis remains unclear. To investigate the impact of short-duration spaceflight on the skin, we conducted skin
Externí odkaz:
https://doaj.org/article/60b54f6af6b24c2694a1e6a88a4f7b8d
Autor:
Alessandra Nerviani, Marie-Astrid Boutet, Giulia Maria Ghirardi, Katriona Goldmann, Elisabetta Sciacca, Felice Rivellese, Elena Pontarini, Edoardo Prediletto, Federico Abatecola, Mattia Caliste, Sara Pagani, Daniele Mauro, Mattia Bellan, Cankut Cubuk, Rachel Lau, Sarah E. Church, Briana M. Hudson, Frances Humby, Michele Bombardieri, Myles J. Lewis, Costantino Pitzalis
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-16 (2024)
Abstract The TAM tyrosine kinases, Axl and MerTK, play an important role in rheumatoid arthritis (RA). Here, using a unique synovial tissue bioresource of patients with RA matched for disease stage and treatment exposure, we assessed how Axl and MerT
Externí odkaz:
https://doaj.org/article/479b8ed47d1c4eb09e9de80de7cc33ef
Autor:
Christine Lundgren, Julia Tutzauer, Sarah E. Church, Olle Stål, Maria Ekholm, Carina Forsare, Bo Nordenskjöld, Mårten Fernö, Pär-Ola Bendahl, Lisa Rydén
Publikováno v:
Breast Cancer Research, Vol 25, Iss 1, Pp 1-20 (2023)
Abstract Background Gene expression (GEX) signatures in breast cancer provide prognostic information, but little is known about their predictive value for tamoxifen treatment. We examined the tamoxifen-predictive value and prognostic effects of diffe
Externí odkaz:
https://doaj.org/article/f09fa8d43985469ab9231f4bffcde4a9
Autor:
Diana Cadena Castaneda, Sonia Jangra, Marina Yurieva, Jan Martinek, Megan Callender, Matthew Coxe, Angela Choi, Juan García-Bernalt Diego, Jianan Lin, Te-Chia Wu, Florentina Marches, Damien Chaussabel, Peter Yu, Andrew Salner, Gabrielle Aucello, Jonathan Koff, Briana Hudson, Sarah E. Church, Kara Gorman, Esperanza Anguiano, Adolfo García-Sastre, Adam Williams, Michael Schotsaert, Karolina Palucka
Publikováno v:
iScience, Vol 26, Iss 8, Pp 107374- (2023)
Summary: The COVID-19 pandemic continues to be a health crisis with major unmet medical needs. The early responses from airway epithelial cells, the first target of the virus regulating the progression toward severe disease, are not fully understood.
Externí odkaz:
https://doaj.org/article/b51b64e50b72469895f79ce437b3fedc
Autor:
Delaney A. Dunne, Kieran A. Cleary, Patrick C. Breysse, Dongwoo T. Chung, Håvard T. Ihle, J. Richard Bond, Hans Kristian Eriksen, Joshua Ott Gundersen, Laura C. Keating, Junhan Kim, Jonas Gahr Sturtzel Lunde, Norman Murray, Hamsa Padmanabhan, Liju Philip, Nils-Ole Stutzer, Doğa Tolgay, Ingunn Katherine Wehus, Sarah E. Church, Todd Gaier, Andrew I. Harris, Richard Hobbs, James W. Lamb, Charles R. Lawrence, Anthony C. S. Readhead, David P. Woody
Publikováno v:
The Astrophysical Journal, Vol 965, Iss 1, p 7 (2024)
We present a new upper limit on the cosmic molecular gas density at z = 2.4–3.4 obtained using the first year of observations from the CO Mapping Array Project (COMAP). COMAP data cubes are stacked on the 3D positions of 243 quasars selected from t
Externí odkaz:
https://doaj.org/article/158a3a89d39041fb9f29208c73a629e2
Autor:
Christine Lundgren, Pär-Ola Bendahl, Sarah E. Church, Maria Ekholm, Mårten Fernö, Carina Forsare, Ute Krüger, Bo Nordenskjöld, Olle Stål, Lisa Rydén
Publikováno v:
npj Breast Cancer, Vol 8, Iss 1, Pp 1-12 (2022)
Abstract PAM50 intrinsic subtyping and risk of recurrence (ROR) score are approved for risk profiling in postmenopausal women. We aimed to examine their long-term prognostic value in terms of breast cancer-free interval (BCFi) and overall survival (O
Externí odkaz:
https://doaj.org/article/6ac42a655e1c44b8aaf372ca6538233d
Autor:
Ilana Schlam, Sarah E. Church, Tyler D. Hether, Krysta Chaldekas, Briana M. Hudson, Andrew M. White, Emily Maisonet, Brent T. Harris, Sandra M. Swain
Publikováno v:
Journal of Translational Medicine, Vol 19, Iss 1, Pp 1-14 (2021)
Abstract Background The characterization of the immune component of the tumor microenvironment (TME) of human epidermal growth factor receptor 2 positive (HER2+) breast cancer has been limited. Molecular and spatial characterization of HER2+ TME of p
Externí odkaz:
https://doaj.org/article/815f26c1bb0147c2a0736d6023a43c34
Autor:
Emily A. Blumberg, Julia Han Noll, Pablo Tebas, Joseph A. Fraietta, Ian Frank, Amy Marshall, Anne Chew, Elizabeth A. Veloso, Alison Carulli, Walter Rogal, Avery L. Gaymon, Aliza H. Schmidt, Tiffany Barnette, Renee Jurek, Rene Martins, Briana M. Hudson, Kalyan Chavda, Christina M. Bailey, Sarah E. Church, Hooman Noorchashm, Wei-Ting Hwang, Carl H. June, Elizabeth O. Hexner
Publikováno v:
JCI Insight, Vol 7, Iss 11 (2022)
BACKGROUND COVID-19 remains a global health emergency with limited treatment options, lagging vaccine rates, and inadequate healthcare resources in the face of an ongoing calamity. The disease is characterized by immune dysregulation and cytokine sto
Externí odkaz:
https://doaj.org/article/6597f6dab218404fa9ecd0f6232979e4
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Externí odkaz:
https://doaj.org/article/934049a8b58e47529bc47e36d0fc94c4
Autor:
Davide Bedognetti, Michele Ceccarelli, Lorenzo Galluzzi, Rongze Lu, Karolina Palucka, Josue Samayoa, Stefani Spranger, Sarah Warren, Kwok-Kin Wong, Elad Ziv, Diego Chowell, Lisa M. Coussens, Daniel D. De Carvalho, David G. DeNardo, Jérôme Galon, Howard L. Kaufman, Tomas Kirchhoff, Michael T. Lotze, Jason J. Luke, Andy J. Minn, Katerina Politi, Leonard D. Shultz, Richard Simon, Vésteinn Thórsson, Joanne B. Weidhaas, Maria Libera Ascierto, Paolo Antonio Ascierto, James M. Barnes, Valentin Barsan, Praveen K. Bommareddy, Adrian Bot, Sarah E. Church, Gennaro Ciliberto, Andrea De Maria, Dobrin Draganov, Winson S. Ho, Heather M. McGee, Anne Monette, Joseph F. Murphy, Paola Nisticò, Wungki Park, Maulik Patel, Michael Quigley, Laszlo Radvanyi, Harry Raftopoulos, Nils-Petter Rudqvist, Alexandra Snyder, Randy F. Sweis, Sara Valpione, Roberta Zappasodi, Lisa H. Butterfield, Mary L. Disis, Bernard A. Fox, Alessandra Cesano, Francesco M. Marincola, Society for Immunotherapy of Cancer (SITC) Cancer Immune Responsiveness Task Force and Working Groups
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 7, Iss 1, Pp 1-23 (2019)
Abstract Tumor immunology has changed the landscape of cancer treatment. Yet, not all patients benefit as cancer immune responsiveness (CIR) remains a limitation in a considerable proportion of cases. The multifactorial determinants of CIR include th
Externí odkaz:
https://doaj.org/article/864f25d06ad04690a4ef2014434f0547