Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Sarah Dysart"'
Autor:
Carlos Stahlhut, Esteban A. Orellana, Kevin Kelnar, Xiaowei Chen, Andrea L. Kasinski, Frank J. Slack, Eliot Shimer, Andreas G. Bader, Sarah Dysart, Jane Zhao
Publikováno v:
Oncogene
Targeted cancer therapies, although often effective, have limited utility owing to preexisting primary or acquired secondary resistance. Consequently, agents are sometimes used in combination to simultaneously affect multiple targets. MicroRNA mimics
Autor:
David R. Brown, Andreas G. Bader, Sarah Dysart, Neil Leatherbury, Paul Lammers, Christopher L. Daige, Jason F. Wiggins, Michael Omotola, Kevin Kelnar, Leslie Priddy, Jane Zhao, Jay Stoudemire
Publikováno v:
Cancer Research. 72:5636-5636
MicroRNA (miRNA) mimics have emerged as a novel class of therapeutics with promising anti-oncogenic activity. These mimics are modeled after naturally occurring tumor suppressor miRNAs that are ubiquitously expressed in normal cells but frequently sh
Autor:
David R. Brown, Andreas G. Bader, Jane Zhao, Chris Daige, Sarah Dysart, Kevin Kelnar, Leslie Priddy
Publikováno v:
Molecular Cancer Therapeutics. 10:C142-C142
Tumor suppressor miRNAs function by regulating multiple cancer-related genes and pathways. The tumor suppressor miRNAs miR-34, let-7, miR-16, miR-26, and miR-145 have proven to be effective in inhibiting tumor growth in mouse models of cancer. Based