Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Sarah Dudley"'
Autor:
Phillip D. Monk, Jody L. Brookes, Victoria J. Tear, Toby N. Batten, Clare Newall, Marcin Mankowski, Michael G. Crooks, Dave Singh, Rekha Chaudhuri, Brian Leaker, Kerry Lunn, Sophie Reynolds, Sarah Dudley, Felicity J. Gabbay, Stephen T. Holgate, Ratko Djukanovic, Thomas MA Wilkinson
Publikováno v:
Respiratory Research, Vol 25, Iss 1, Pp 1-17 (2024)
Abstract Background Respiratory viral infections are major drivers of chronic obstructive pulmonary disease (COPD) exacerbations. Interferon-β is naturally produced in response to viral infection, limiting replication. This exploratory study aimed t
Externí odkaz:
https://doaj.org/article/0e45758b1a514217839b388bd5252764
Publikováno v:
Journal of Perinatology. 42:1703-1707
A patent ductus arteriosus (PDA) in infants born premature can present significant management challenges for neonatal providers. Quantifying a hemodynamically significant PDA (hsPDA) represents the first hurdle, however, identifying the best evidence
Autor:
Pedro Mb Rodrigues, Marcin Mankowski, Salman Siddiqui, Angela Thompson, Ratko Djukanovic, Davinder Dosanjh, Najib M. Rahman, Richard J Marsden, Victoria Tear, Sandra Aitken, Toby N Batten, Jody Brookes, Alastair Watson, Tristan W Clark, Tom Wilkinson, Dave Singh, Sophie Hemmings, Lorcan McGarvey, Michael G. Crooks, Phillip Monk, Felicity J Gabbay, Stephen T. Holgate, Tim Harrison, Edmund Foster, Donna E. Davies, Adam Fleet, Ling-Pei Ho, Alex Horsley, Sarah Dudley, Dinesh Saralaya, Rona Beegan, Jacklyn A Smith
Publikováno v:
The Lancet Respiratory Medicine
Monk, P D, Marsden, R J, Tear, V J, Brookes, J, Batten, T N, Mankowski, M, Gabbay, F J, Davies, D E, Holgate, S T, Ho, L-P, Clark, T, Djukanovic, R, Wilkinson, T M A & Group, I I B COVID S 2021, ' Safety and efficacy of inhaled nebulised interferon beta-1a (SNG001) for treatment of SARS-CoV-2 infection: a randomised, double-blind, placebo-controlled, phase 2 trial ', The Lancet. Respiratory medicine, vol. 9, no. 2, pp. 196—206 . https://doi.org/10.1016/s2213-2600(20)30511-7
Monk, P D, Marsden, R J, Tear, V J, Brookes, J, Batten, T N, Mankowski, M, Gabbay, F J, Davies, D E, Holgate, S T, Ho, L-P, Clark, T, Djukanovic, R, Wilkinson, T M A & Group, I I B COVID S 2021, ' Safety and efficacy of inhaled nebulised interferon beta-1a (SNG001) for treatment of SARS-CoV-2 infection: a randomised, double-blind, placebo-controlled, phase 2 trial ', The Lancet. Respiratory medicine, vol. 9, no. 2, pp. 196—206 . https://doi.org/10.1016/s2213-2600(20)30511-7
BackgroundSevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection carries a substantial risk of severe and prolonged illness; treatment options are currently limited. We assessed the efficacy and safety of inhaled nebulised interferon
Autor:
Sarah Dudley, Stacy J. Park, A. Sarah Walker, Nicole Stoesser, Tim E. A. Peto, Kasi Vegesana, Shireen Meher Kotay, Derrick W. Crook, Amy J. Mathers, Hardik I. Parikh, Katie E. Barry
Publikováno v:
Applied and Environmental Microbiology. 86
Background:Hospital wastewater is an increasingly recognized reservoir for resistant Gramnegative organisms. Factors involved in establishment and persistence of Klebsiella pneumoniae carbapenemase-producing organisms (KPCO) in hospital wastewater pl
Autor:
Stacy C, Park, Hardik, Parikh, Kasi, Vegesana, Nicole, Stoesser, Katie E, Barry, Shireen M, Kotay, Sarah, Dudley, Timothy E A, Peto, Derrick W, Crook, A Sarah, Walker, Amy J, Mathers
Publikováno v:
Applied and Environmental Microbiology
Klebsiella pneumoniae carbapenemase-producing organisms (KPCOs) are bacteria that are resistant to most antibiotics and thus are challenging to treat when they cause infections in patients. These organisms can be acquired by patients who are hospital
Autor:
Tim E. A. Peto, A. Sarah Walker, Derrick W. Crook, Hardik I. Parikh, Katie E. Barry, Stacy J. Park, Nicole Stoesser, Shireen Meher Kotay, Sarah Dudley, Kasi Vegesana, Amy J. Mathers
Publikováno v:
SSRN Electronic Journal.
Background: Hospital wastewater is an increasingly recognized reservoir for resistant Gram-negative organisms. Factors involved in establishment and persistence of Klebsiella pneumoniae carbapenemase-producing organisms (KPCO) in hospital wastewater
Autor:
Patrick Dennison, Stephen T. Holgate, Nivenka Jayasekera, Claudia Traidl-Hoffmann, Heidrun Behrendt, Sarah Dudley, Carsten B. Schmidt-Weber, Peter H. Howarth, Cornelia Blume, Phillip Monk, Donna E. Davies, Emily J. Swindle
Publikováno v:
Eur. Respir. J. 42, 87-97 (2013)
The airway epithelium forms a physical, chemical and immunological barrier against inhaled environmental substances. In asthma, these barrier properties are thought to be abnormal. In this study, we analysed the effect of grass pollen on the physical
Autor:
Ratko, Djukanović, Tim, Harrison, Sebastian L, Johnston, Flic, Gabbay, Peter, Wark, Neil C, Thomson, Robert, Niven, Dave, Singh, Helen K, Reddel, Donna E, Davies, Richard, Marsden, Christine, Boxall, Sarah, Dudley, Vincent, Plagnol, Stephen T, Holgate, Phillip, Monk, Joanna, Samways
Publikováno v:
American Journal of Respiratory and Critical Care Medicine
Rationale: Ex vivo, bronchial epithelial cells from people with asthma are more susceptible to rhinovirus infection caused by deficient induction of the antiviral protein, IFN-β. Exogenous IFN-β restores antiviral activity. Objectives: To compare t