Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Sarah Dedeurwaerder"'
Autor:
Rachel Deplus, Loïc Blanchon, Arumugam Rajavelu, Abdelhalim Boukaba, Matthieu Defrance, Judith Luciani, Françoise Rothé, Sarah Dedeurwaerder, Hélène Denis, Arie B. Brinkman, Femke Simmer, Fabian Müller, Benjamin Bertin, Maria Berdasco, Pascale Putmans, Emilie Calonne, David W. Litchfield, Yvan de Launoit, Tomasz P. Jurkowski, Hendrik G. Stunnenberg, Christoph Bock, Christos Sotiriou, Mario F. Fraga, Manel Esteller, Albert Jeltsch, François Fuks
Publikováno v:
Cell Reports, Vol 8, Iss 3, Pp 743-753 (2014)
DNA methylation is a central epigenetic modification that is established by de novo DNA methyltransferases. The mechanisms underlying the generation of genomic methylation patterns are still poorly understood. Using mass spectrometry and a phosphospe
Externí odkaz:
https://doaj.org/article/a2e48f8c7f1944aaba57f0d1231bcd9a
Autor:
Dragan Milenkovic, Wim Vanden Berghe, Céline Boby, Christine Leroux, Ken Declerck, Katarzyna Szarc vel Szic, Karen Heyninck, Kris Laukens, Martin Bizet, Matthieu Defrance, Sarah Dedeurwaerder, Emilie Calonne, Francois Fuks, Guy Haegeman, Guido R M M Haenen, Aalt Bast, Antje R Weseler
Publikováno v:
PLoS ONE, Vol 9, Iss 4, p e95527 (2014)
In a recent intervention study, the daily supplementation with 200 mg monomeric and oligomeric flavanols (MOF) from grape seeds for 8 weeks revealed a vascular health benefit in male smokers. The objective of the present study was to determine the im
Externí odkaz:
https://doaj.org/article/66dc8ff740ab4f338d19887c8d8c09cb
Autor:
Martin Bizet, Pushpamali De Silva, Sarah Dedeurwaerder, Françoise Bex, Jean Nicolas Lodewyckx, Matthieu Defrance, Hugues Duvillier, François Fuks, Soizic Garaud, Karen Willard-Gallo, Chunyan Gu-Trantien, Florence Roufosse
Publikováno v:
European Journal of Immunology. 47:168-179
The forkhead box P1 (FOXP1) transcription factor has been shown to regulate the generation and maintenance of quiescent naive murine T cells. In humans, FOXP1 expression has been correlated with overall survival in patients with peripheral T-cell lym
Autor:
Hélène Denis, François Fuks, Françoise Rothé, Emilie Calonne, Olivier Van Grembergen, Benjamin Delatte, Pascale Putmans, Christos Sotiriou, Rachel Deplus, Sarah Dedeurwaerder
Publikováno v:
Molecular BioSystems. 12:404-413
MicroRNAs (miRNAs) are small non-coding RNAs that post-transcriptionally regulate gene expression. Alteration of miRNA levels is common in tumors and contributes to the pathogenesis of human malignancies. In the present study we examined the role pla
Autor:
Evelyne, Collignon, Annalisa, Canale, Clémence, Al Wardi, Martin, Bizet, Emilie, Calonne, Sarah, Dedeurwaerder, Soizic, Garaud, Céline, Naveaux, Whitney, Barham, Andrew, Wilson, Sophie, Bouchat, Pascale, Hubert, Carine, Van Lint, Fiona, Yull, Christos, Sotiriou, Karen, Willard-Gallo, Agnès, Noel, François, Fuks
Publikováno v:
Science advances. 4(6)
Ten-eleven translocation enzymes (TET1, TET2, and TET3), which induce DNA demethylation and gene regulation by converting 5-methylcytosine (5mC) to 5-hydroxymethylcytosine (5hmC), are often down-regulated in cancer. We uncover, in basal-like breast c
Autor:
Karin B. Michels, Christoph Bock, Aleksandar Milosavljevic, Charles B. Epstein, Alexander Meissner, John M. Greally, Kimberly D. Siegmund, E. Andres Houseman, Rafael A. Irizarry, Benedetta Izzi, Sarah Dedeurwaerder, Karl T. Kelsey, Ivo Gut, Alexandra M. Binder
Publikováno v:
Nature Methods. 10:949-955
Epigenome-wide association studies (EWAS) hold promise for the detection of new regulatory mechanisms that may be susceptible to modification by environmental and lifestyle factors affecting susceptibility to disease. Epigenome-wide screening methods
Autor:
François Fuks, Martin Bizet, Matthieu Defrance, Emilie Calonne, Gianluca Bontempi, Sarah Dedeurwaerder
Publikováno v:
Briefings in Bioinformatics
Infinium HumanMethylation450 beadarray is a popular technology to explore DNA methylomes in health and disease, and there is a current explosion in the use of this technique. Despite experience acquired from gene expression microarrays, analyzing Inf
Autor:
Gilles Duverlie, Czeslaw Wychowski, Carole Fournier, Catherine François, Virginie Morel, Véronique Descamps, François Helle, Sandrine Castelain, Sarah Dedeurwaerder
Publikováno v:
Journal of General Virology. 94:996-1008
A trans-packaging system for hepatitis C virus (HCV) replicons lacking envelope glycoproteins was developed. The replicons were efficiently encapsidated into infectious particles after expression in trans of homologous HCV envelope proteins under the
Autor:
Sarah Dedeurwaerder, Soizic Garaud, Gianluca Bontempi, François Fuks, Emilie Calonne, Gert Van den Eynden, Karen Willard Gallo, Denis Larsimont, Alexander Koch, Matthieu Defrance, Roberto Salgado, Christos Sotiriou, Jana Jeschke, Christine Desmedt, Martin Bizet
Publikováno v:
The Journal of clinical investigation. 127(8)
BACKGROUND The tumor immune response is increasingly associated with better clinical outcomes in breast and other cancers. However, the evaluation of tumor-infiltrating lymphocytes (TILs) relies on histopathological measurements with limited accuracy
Autor:
Soizic, Garaud, Florence, Roufosse, Pushpamali, De Silva, Chunyan, Gu-Trantien, Jean-Nicolas, Lodewyckx, Hugues, Duvillier, Sarah, Dedeurwaerder, Martin, Bizet, Matthieu, Defrance, François, Fuks, Françoise, Bex, Karen, Willard-Gallo
Publikováno v:
European journal of immunology. 47(1)
The forkhead box P1 (FOXP1) transcription factor has been shown to regulate the generation and maintenance of quiescent naïve murine T cells. In humans, FOXP1 expression has been correlated with overall survival in patients with peripheral T-cell ly