Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Sarah Daley"'
Autor:
Roberto Collu, Zheng Yin, Elisa Giunti, Sarah Daley, Mei Chen, Peter Morin, Richard Killick, Stephen T. C. Wong, Weiming Xia
Publikováno v:
Frontiers in Aging Neuroscience, Vol 16 (2024)
IntroductionThe goal of this study is to explore the pharmacological potential of the amyloid-reducing vasodilator fasudil, a selective Ras homolog (Rho)-associated kinases (ROCK) inhibitor, in the P301S tau transgenic mouse model (Line PS19) of neur
Externí odkaz:
https://doaj.org/article/738526ed29cf4602848657bb379d4868
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 168, Iss , Pp 115756- (2023)
Background: Hypertension and hyperlipidemia are considered risk factors for Alzheimer’s disease (AD) and other related dementias. Clinically approved medications typically prescribed to manage these conditions have shown an association with reduced
Externí odkaz:
https://doaj.org/article/582605138ccc4bbb99239219f48bcd68
Autor:
Katherine W. Turk, Alexandra Geada, Victor E. Alvarez, Weiming Xia, Jonathan D. Cherry, Raymond Nicks, Gaoyuan Meng, Sarah Daley, Yorghos Tripodis, Bertrand R. Huber, Andrew E. Budson, Brigid Dwyer, Neil W. Kowall, Robert C. Cantu, Lee E. Goldstein, Douglas I. Katz, Robert A. Stern, Michael L. Alosco, Jesse Mez, Ann C. McKee, Thor D. Stein
Publikováno v:
Alzheimer’s Research & Therapy, Vol 14, Iss 1, Pp 1-12 (2022)
Abstract Background Cerebrospinal fluid (CSF) tau and beta-amyloid levels in chronic traumatic encephalopathy (CTE), a disease which can be clinically indistinguishable from Alzheimer’s disease (AD), are largely unknown. We examined postmortem CSF
Externí odkaz:
https://doaj.org/article/4f7f418230ce468aace772cfd97ce8e6
Autor:
Jonathan D. Cherry, Gaoyuan Meng, Sarah Daley, Weiming Xia, Sarah Svirsky, Victor E. Alvarez, Raymond Nicks, Morgan Pothast, Hunter Kelley, Bertrand Huber, Yorghos Tripodis, Michael L. Alosco, Jesse Mez, Ann C. McKee, Thor D. Stein
Publikováno v:
Journal of Neuroinflammation, Vol 17, Iss 1, Pp 1-12 (2020)
Abstract Background Neuroinflammation has been implicated in the pathogenesis of chronic traumatic encephalopathy (CTE), a progressive neurodegenerative disease association with exposure to repetitive head impacts (RHI) received though playing contac
Externí odkaz:
https://doaj.org/article/f86c5fd4709d442c9de2bc0be5e08412
Autor:
Minali Prasad, Jia Xu, Joshua S. Agranat, Weiming Xia, Sarah Daley, Steven Ness, Xuejing Chen, Nicole H. Siegel, Thor D. Stein, Jaeyoon Chung, Manju L. Subramanian
Publikováno v:
Life, Vol 13, Iss 1, p 118 (2022)
The purpose of this study is to characterize the inflammatory cytokine profile in rhegmatogenous retinal detachments (RRDs) compared to surgical controls. Vitreous humor was collected from patients undergoing vitrectomy for RRD and noninflammatory vi
Externí odkaz:
https://doaj.org/article/77893be634b54a26af482fdea2c281f0
Autor:
Michael L Alosco, Monica Ly, Sydney Mosaheb, Nicole Saltiel, Madeline Uretsky, Yorghos Tripodis, Brett Martin, Joseph Palmisano, Lisa Delano-Wood, Mark W Bondi, Gaoyuan Meng, Weiming Xia, Sarah Daley, Lee E Goldstein, Douglas I Katz, Brigid Dwyer, Daniel H Daneshvar, Christopher Nowinski, Robert C Cantu, Neil W Kowall, Robert A Stern, Victor E Alvarez, Jesse Mez, Bertrand Russell Huber, Ann C McKee, Thor D Stein
Publikováno v:
Brain communications, vol 5, iss 2
American football players and other individuals exposed to repetitive head impacts can exhibit a constellation of later-life cognitive and neuropsychiatric symptoms. While tau-based diseases such as chronic traumatic encephalopathy can underpin certa
Autor:
Daniel, Kirsch, Arsal, Shah, Erin, Dixon, Hunter, Kelley, Jonathan D, Cherry, Weiming, Xia, Sarah, Daley, Nurgul, Aytan, Kerry, Cormier, Carol, Kubilus, Rebecca, Mathias, Victor E, Alvarez, Bertrand R, Huber, Ann C, McKee, Thor D, Stein
Publikováno v:
J Neuropathol Exp Neurol
Chronic traumatic encephalopathy (CTE) is a neurodegenerative disease linked to repetitive head impacts (RHI) and characterized by perivascular hyperphosphorylated tau (p-tau) deposits. The role of vascular injury, blood-brain barrier leakage, and ne
Autor:
Jesse Mez, Erin Dixon, Lucas Fishbein, Gaoyuan Meng, Bertrand R. Huber, Camille D. Esnault, Michael L. Alosco, Thor D. Stein, Jonathan D. Cherry, Hunter Kelley, Sarah Daley, Ann C. McKee, Robert McCormack, Yorghos Tripodis, SpiroAnthony Stathas, Arsal Shah, Weiming Xia, Raymond Nicks, Victor E. Alvarez, Morgan Pothast
Publikováno v:
Alzheimer'sdementia : the journal of the Alzheimer's Association. 18(8)
INTRODUCTION Chronic traumatic encephalopathy (CTE) is a neurodegenerative tauopathy associated with repetitive head impacts (RHI) typically sustained by contact sport athletes. Post-translation modifications to tau in CTE have not been well delineat
Autor:
Neil W. Kowall, Jonathan D. Cherry, Douglas I. Katz, Ann C. McKee, Jesse Mez, Katherine W. Turk, Brigid Dwyer, Victor E. Alvarez, Raymond Nicks, Gaoyuan Meng, Weiming Xia, Alexandra Geada, Robert S. Stern, Bertrand R. Huber, Robert C. Cantu, Lee E. Goldstein, Michael L. Alosco, Sarah Daley, Thor D. Stein, Andrew E. Budson, Yorghos Tripodis
Publikováno v:
Alzheimer’s Research & Therapy, Vol 14, Iss 1, Pp 1-12 (2022)
Background Cerebrospinal fluid (CSF) tau and beta-amyloid levels in chronic traumatic encephalopathy (CTE), a disease which can be clinically indistinguishable from Alzheimer’s disease (AD), are largely unknown. We examined postmortem CSF analytes
Autor:
Jennifer Thorn, Nathan Tanoue, M. Bernas, Pawel R. Kiela, J. Steven Alexander, Marlys H. Witte, Sarah Daley, Jalicia Washington
Publikováno v:
Inflamm Bowel Dis
BackgroundInflammatory bowel disease (IBD) is characterized by chronic inflammation, which can progress to colorectal cancer, with duration of disease being the most important risk factor. Although many factors are involved, the pathogenic link betwe