Výsledky vyhledávání - "Sarah D'Annunzio"

Akademický článek

Oncogenic enhancers prime quiescent metastatic cells to escape NK immune surveillance by eliciting transcriptional memory

Publikováno v: Nature Communications, Vol 15, Iss 1, Pp 1-24 (2024)

Abstract Metastasis arises from disseminated tumour cells (DTCs) that are characterized by intrinsic phenotypic plasticity and the capability of seeding to secondary organs. DTCs can remain latent for years before giving rise to symptomatic overt met

Externí odkaz: https://doaj.org/article/f053b57e57204e48bf78051e5364cb8f

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Quantitative Analysis of PcG-Associated Condensates by Stochastic Optical Reconstruction Microscopy (STORM)

Autor: Silvia Scalisi, Ali Ahmad, Sarah D’Annunzio, David Rousseau, Alessio Zippo

Publikováno v: Methods in Molecular Biology ISBN: 9781071631423

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::a9d2ebf14b7fe56480e0172af52c03de
https://doi.org/10.1007/978-1-0716-3143-0_14

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On the robustness of machine learning algorithms toward microfluidic distortions for cell classification

Autor: Ali, Ahmad, Federico, Sala, Petra, Paiè, Alessia, Candeo, Sarah, D'Annunzio, Alessio, Zippo, Carole, Frindel, Roberto, Osellame, Francesca, Bragheri, Andrea, Bassi, David, Rousseau

Publikováno v: Lab on a chip. 22(18)

Single-cell imaging and sorting are critical technologies in biology and clinical applications. The power of these technologies is increased when combined with microfluidics, fluorescence markers, and machine learning. However, this quest faces sever

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::f5b97220cc22e8d7d101611ecec84e50
https://pubmed.ncbi.nlm.nih.gov/35946995

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The Methylation Analysis of the Glucose-Dependent Insulinotropic Polypeptide Receptor (GIPR) Locus in GH-Secreting Pituitary Adenomas

Autor: Mattia Dalle Nogare, Sarah D’Annunzio, Giovanni Vazza, Daniela Regazzo, Luna Picello, Luca Denaro, Giacomo Voltan, Carla Scaroni, Filippo Ceccato, Gianluca Occhi

Publikováno v: International Journal of Molecular Sciences; Volume 24; Issue 11; Pages: 9264

The glucose-dependent insulinotropic polypeptide receptor (GIPR) is aberrantly expressed in about one-third of GH-secreting pituitary adenomas (GH-PAs) and has been associated with a paradoxical increase of GH after a glucose load. The reason for suc

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::33a97ba2c6591a68ec3a10a68db4c36f
https://doi.org/10.3390/ijms24119264

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On the robustness of machine learning algorithms toward microfluidic distortions for cell classification via on-chip fluorescence microscopy

Autor: Ali Ahmad, Federico Sala, Petra Paiè, Alessia Candeo, Sarah D'Annunzio, Alessio Zippo, Carole Frindel, Roberto Osellame, Francesca Bragheri, Andrea Bassi, David Rousseau

Machine learning algorithms for cell classification via on-chip fluorescence microscopy are shown to be robust to microfluidic distortions due to cell displacement during acquisition.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dc96d7d323672381b9901645362a0bea
https://hdl.handle.net/11311/1220346

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Inhibition of Heat Shock Factor 1 Enhances Repressive Molecular Mechanisms on the POMC Promoter

Autor: Sarah D'Annunzio, Marily Theodoropoulou, José Garcia, Marcelo Paez-Pereda, Ran Li, Denis Ciato, Guenter K. Stalla, Lilia Papst, Michael Hristov, Liudmila Rozhinskaya, Michael Buchfelder, Maria A. Tichomirowa, Zhanna E. Belaya

Publikováno v: Neuroendocrinology. 109:362-373

Background: Cushing’s disease (CD) is caused by adrenocorticotropic hormone (ACTH)-secreting pituitary tumours. They express high levels of heat shock protein 90 and heat shock factor 1 (HSF1) in comparison to the normal tissue counterpart, indicat

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::74da66fca493c81b2fdef9ce4c3c4579
https://doi.org/10.1159/000500200

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High-throughput 3D imaging of single cells with light-sheet fluorescence microscopy on chip

Autor: Federico Sala, Petra Paiè, Andrea Bassi, Francesca Bragheri, Roberto Osellame, Sarah D'Annunzio, Andrea Farina, Alessio Zippo, Michele Castriotta

Publikováno v: Biomed Opt Express
Biomedical optics express 11 (2020): 4397–4407. doi:10.1364/BOE.393892
info:cnr-pdr/source/autori:Sala, Federico; Castriotta, Michele; Paie, Petra; Farina, Andrea; D'Annunzio, Sarah; Zippo, Alessio; Osellame, Roberto; Bragheri, Francesca; Bassi, Andrea/titolo:High-throughput 3D imaging of single cells with light-sheet fluorescence microscopy on chip/doi:10.1364%2FBOE.393892/rivista:Biomedical optics express/anno:2020/pagina_da:4397/pagina_a:4407/intervallo_pagine:4397–4407/volume:11

Single-cell analysis techniques are fundamental to study the heterogeneity of cellular populations, which is the basis to understand several biomedical mechanisms. Light-sheet fluorescence microscopy is a powerful technique for obtaining high-resolut

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d000823c534bbb50e75372b2df75d034
https://pubmed.ncbi.nlm.nih.gov/32923051

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MLL4-associated condensates counterbalance Polycomb-mediated nuclear mechanical stress in Kabuki syndrome

Publikováno v: Nature genetics
(2020). doi:10.1038/s41588-020-00724-8
info:cnr-pdr/source/autori:Fasciani, Alessandra; D'Annunzio, Sarah; Poli, Vittoria; Fagnocchi, Luca; Beyes, Sven; Michelatti, Daniela; Corazza, Francesco; Antonelli, Laura; Gregoretti, Francesco; Oliva, Gennaro; Belli, Romina; Peroni, Daniele; Domenici, Enrico; Zambrano, Samuel; Intartaglia, Daniela; Settembre, Carmine; Conte, Ivan; Testi, Claudia; Vergyris, Panagiotis; Ruocco, Giancarlo; Zippo, Alessio/titolo:MLL4-associated condensates counterbalance Polycomb-mediated nuclear mechanical stress in Kabuki syndrome/doi:10.1038%2Fs41588-020-00724-8/rivista:Nature genetics (Print)/anno:2020/pagina_da:/pagina_a:/intervallo_pagine:/volume

The genetic elements required to tune gene expression are partitioned in active and repressive nuclear condensates. Chromatin compartments include transcriptional clusters whose dynamic establishment and functioning depend on multivalent interactions

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1f23dbfafd94ec8a2fb0fa759da75a74

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Inhibition of Heat Shock Factor 1 Enhances Repressive Molecular Mechanisms on the POMC Promoter

Autor: Denis, Ciato, Ran, Li, Jose Luis, Monteserin Garcia, Lilia, Papst, Sarah, D'Annunzio, Michael, Hristov, Maria A, Tichomirowa, Zhanna, Belaya, Liudmila, Rozhinskaya, Michael, Buchfelder, Marily, Theodoropoulou, Marcelo, Paez-Pereda, Günter Karl, Stalla

Publikováno v: Neuroendocrinology. 109(4)

Cushing's disease (CD) is caused by adrenocorticotropic hormone (ACTH)-secreting pituitary tumours. They express high levels of heat shock protein 90 and heat shock factor 1 (HSF1) in comparison to the normal tissue counterpart, indicating activated

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::94206c1e3647de26b237778893ae0d9b
https://pubmed.ncbi.nlm.nih.gov/30995664

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