Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Sarah Christine Christensen"'
Autor:
Simone S. E. Nielsen, Mikkel R. Holst, Kristine Langthaler, Sarah Christine Christensen, Elisabeth Helena Bruun, Birger Brodin, Morten S. Nielsen
Publikováno v:
Fluids and Barriers of the CNS, Vol 20, Iss 1, Pp 1-15 (2023)
Abstract The detailed mechanisms by which the transferrin receptor (TfR) and associated ligands traffic across brain capillary endothelial cells (BECs) of the CNS-protective blood–brain barrier constitute an important knowledge gap within maintenan
Externí odkaz:
https://doaj.org/article/19b7d12e1ec14ff993d47e4deb7c4783
Autor:
Simone S. E. Nielsen, Mikkel R. Holst, Kristine Langthaler, Sarah Christine Christensen, Elisabeth Helena Bruun, Birger Brodin, Morten S. Nielsen
Publikováno v:
Fluids and Barriers of the CNS, Vol 20, Iss 1, Pp 1-1 (2023)
Externí odkaz:
https://doaj.org/article/cb47c09022c14128b021dc70e4145a71
Autor:
Diána Hudecz, Sara Björk Sigurdardóttir, Sarah Christine Christensen, Casper Hempel, Andrew J Urquhart, Thomas Lars Andresen, Morten S Nielsen
Publikováno v:
PLoS ONE, Vol 16, Iss 4, p e0249686 (2021)
The blood-brain barrier (BBB) is one of the main obstacles for therapies targeting brain diseases. Most macromolecules fail to pass the tight BBB, formed by brain endothelial cells interlinked by tight junctions. A wide range of small, lipid-soluble
Externí odkaz:
https://doaj.org/article/922698fa4c0a47eb9b69cb886bed49d9
Publikováno v:
Christensen, S C, Hudecz, D, Jensen, A, Christensen, S & Nielsen, M S 2021, ' Basigin Antibodies with Capacity for Drug Delivery Across Brain Endothelial Cells ', Molecular Neurobiology, vol. 58, no. 9, pp. 4392-4403 . https://doi.org/10.1007/s12035-021-02421-x
The blood-brain barrier (BBB) poses challenges for delivering antibody-based therapeutics to the brain and is a main obstacle for the successful application of biotherapeutics for the treatment of brain disorders. As only a small fraction of monoclon
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dd914f168c955dba84b6be71872ff92b
https://pure.au.dk/portal/da/publications/basigin-antibodies-with-capacity-for-drug-delivery-across-brain-endothelial-cells(ef61b234-f92b-4ffe-bc03-8f8ff6b2d9d4).html
https://pure.au.dk/portal/da/publications/basigin-antibodies-with-capacity-for-drug-delivery-across-brain-endothelial-cells(ef61b234-f92b-4ffe-bc03-8f8ff6b2d9d4).html
Autor:
Andrew J. Urquhart, Sara Björk Sigurdardóttir, Sarah Christine Christensen, Thomas Lars Andresen, Morten Nielsen, Diána Hudecz, Casper Hempel
Publikováno v:
Hudecz, D, Sigurdardóttir, S B, Christensen, S C, Hempel, C, Urquhart, A J, Andresen, T L & Nielsen, M S 2021, ' Two peptides targeting endothelial receptors are internalized into murine brain endothelial cells ', PLOS ONE, vol. 16, no. 4, e0249686 . https://doi.org/10.1371/journal.pone.0249686
Hudecz, D, Sigurdardóttir, S B, Christensen, S C, Hempel, C, Urquhart, A J, Andresen, T L & Nielsen, M S 2021, ' Two peptides targeting endothelial receptors are internalized into murine brain endothelial cells ', PLOS ONE, vol. 16, e0249686 . https://doi.org/10.1371/journal.pone.0249686
PLoS ONE
PLoS ONE, Vol 16, Iss 4, p e0249686 (2021)
Hudecz, D, Sigurdardóttir, S B, Christensen, S C, Hempel, C, Urquhart, A J, Andresen, T L & Nielsen, M S 2021, ' Two peptides targeting endothelial receptors are internalized into murine brain endothelial cells ', PLOS ONE, vol. 16, e0249686 . https://doi.org/10.1371/journal.pone.0249686
PLoS ONE
PLoS ONE, Vol 16, Iss 4, p e0249686 (2021)
The blood-brain barrier (BBB) is one of the main obstacles for therapies targeting brain diseases. Most macromolecules fail to pass the tight BBB, formed by brain endothelial cells interlinked by tight junctions. A wide range of small, lipid-soluble
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fa30e19fe0204ed8693055ee68d52673
https://pure.au.dk/portal/da/publications/two-peptides-targeting-endothelial-receptors-are-internalized-into-murine-brain-endothelial-cells(c5af39a7-7a79-4414-9886-948bc7fdee5c).html
https://pure.au.dk/portal/da/publications/two-peptides-targeting-endothelial-receptors-are-internalized-into-murine-brain-endothelial-cells(c5af39a7-7a79-4414-9886-948bc7fdee5c).html
Autor:
Sarah Christine, Christensen, Diána, Hudecz, Allan, Jensen, Søren, Christensen, Morten Schallburg, Nielsen
Publikováno v:
Molecular neurobiology. 58(9)
The blood-brain barrier (BBB) poses challenges for delivering antibody-based therapeutics to the brain and is a main obstacle for the successful application of biotherapeutics for the treatment of brain disorders. As only a small fraction of monoclon
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::da8245ab81ccfde7e5d28bff94fd453d
https://pubmed.ncbi.nlm.nih.gov/34014436
https://pubmed.ncbi.nlm.nih.gov/34014436
Autor:
Christian Brix Folsted Andersen, Morten Nielsen, Allan Jensen, Berit Olsen Krogh, Sarah Christine Christensen, Søren Christensen
Publikováno v:
Christensen, S C, Krogh, B O, Jensen, A, Andersen, C B F, Christensen, S & Nielsen, M S 2020, ' Characterization of basigin monoclonal antibodies for receptor-mediated drug delivery to the brain ', Scientific Reports, vol. 10, no. 1, 14582 . https://doi.org/10.1038/s41598-020-71286-2
Scientific Reports
Scientific Reports, Vol 10, Iss 1, Pp 1-13 (2020)
Scientific Reports
Scientific Reports, Vol 10, Iss 1, Pp 1-13 (2020)
The brain uptake of biotherapeutics for brain diseases is hindered by the blood–brain barrier (BBB). The BBB selectively regulates the transport of large molecules into the brain and thereby maintains brain homeostasis. Receptor-mediated transcytos
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::94d10d1b784d7aa71aca17e057b9359e
https://doi.org/10.1038/s41598-020-71286-2
https://doi.org/10.1038/s41598-020-71286-2