Common schizophrenia risk variants are enriched in open chromatin regions of human glutamatergic neurons

Autor: Mads E. Hauberg, Jordi Creus-Muncunill, Jaroslav Bendl, Alexey Kozlenkov, Biao Zeng, Chuhyon Corwin, Sarah Chowdhury, Harald Kranz, Yasmin L. Hurd, Michael Wegner, Anders D. Børglum, Stella Dracheva, Michelle E. Ehrlich, John F. Fullard, Panos Roussos

Publikováno v: Nature Communications, Vol 11, Iss 1, Pp 1-16 (2020)

Here, the authors perform ATAC-seq on four distinct cell populations from three different regions of the human brain, finding that chromatin accessibility varies greatly by cell type and less by brain region. This study reveals differences in biologi

Externí odkaz: https://doaj.org/article/91a74a493df14309930cea9170546613

Coherent Random Lasing in Subwavelength Quasi‐2D Perovskites

Autor: Colton Fruhling, Kang Wang, Sarah Chowdhury, Xiaohui Xu, Jeffrey Simon, Alexander Kildishev, Letian Dou, Xiangeng Meng, Alexandra Boltasseva, Vladimir M. Shalaev

Publikováno v: Laser & Photonics Reviews. 17

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::6dadb0c0f1c8397b8d777c02ea8da82a
https://doi.org/10.1002/lpor.202200314

Deletion of the microglial transmembrane immune signaling adaptor TYROBP ameliorates Huntington’s disease mouse phenotype

Autor: Jordi Creus-Muncunill, Daniele Mattei, Joanna Bons, Angie V. Ramirez-Jimenez, B. Wade Hamilton, Chuhyon Corwin, Sarah Chowdhury, Birgit Schilling, Lisa Ellerby, Michelle E. Ehrlich

BACKGROUNDHuntington’s disease (HD) is a fatal neurodegenerative disorder caused by an expansion of the CAG trinucleotide repeat in the huntingtin gene. Immune activation is abundant in the striatum of HD patients. Detection of active microglia at

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::bce1fd1e242772557d07b5d5971fea0d
https://doi.org/10.1101/2022.02.18.480944

Common schizophrenia risk variants are enriched in open chromatin regions of human glutamatergic neurons

Autor: John F. Fullard, Mads E. Hauberg, Sarah Chowdhury, Stella Dracheva, Michael Wegner, Jaroslav Bendl, Chuhyon Corwin, Panos Roussos, Alexey Kozlenkov, Biao Zeng, Yasmin L. Hurd, Anders D. Børglum, Jordi Creus-Muncunill, Harald Kranz, Michelle E. Ehrlich

Publikováno v: Nature Communications
Hauberg, M E, Creus-Muncunill, J, Bendl, J, Kozlenkov, A, Zeng, B, Corwin, C, Chowdhury, S, Kranz, H, Hurd, Y L, Wegner, M, Børglum, A D, Dracheva, S, Ehrlich, M E, Fullard, J F & Roussos, P 2020, ' Common schizophrenia risk variants are enriched in open chromatin regions of human glutamatergic neurons ', Nature Communications, vol. 11, 5581 . https://doi.org/10.1038/s41467-020-19319-2
Nature Communications, Vol 11, Iss 1, Pp 1-16 (2020)

The chromatin landscape of human brain cells encompasses key information to understanding brain function. Here we use ATAC-seq to profile the chromatin structure in four distinct populations of cells (glutamatergic neurons, GABAergic neurons, oligode

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::72e5310df8f984cbda1e2505815111b0
https://doi.org/10.1038/s41467-020-19319-2

Determinants of Personnel Differentiation for Competitive Advantage: From the Perspective of Customer Satisfaction

Autor: Rifat Parveen Bokhari, Sarah Chowdhury

Publikováno v: IOSR Journal of Business and Management. 16:22-29

Personnel differentiation has been viewed as one of the immeasurable competitive advantage for the service sector in the world. Such advantage or human resource based advantage is difficult for a competitor to imitate because the source of the advant

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::f6639379a02d115a5d189aff2b5d563c
https://doi.org/10.9790/487x-16822229