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Autor:
Sarah Ceylan Krassnig, Marina Mäser, Nicola Anna Probst, Jens Werner, Charlotte Schlett, Nina Schumann, Gudrun von Scheven, Aswin Mangerich, Alexander Bürkle
Publikováno v:
Toxicology Reports, Vol 10, Iss , Pp 171-189 (2023)
Chlorambucil (CLB) belongs to the class of nitrogen mustards (NMs), which are highly reactive bifunctional alkylating agents and were the first chemotherapeutic agents developed. They form DNA interstrand crosslinks (ICLs), which cause a blockage of
Externí odkaz:
https://doaj.org/article/4cf2e1ac875444ff9edb92dd65be03db