Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Sarah Calhoun"'
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-13 (2022)
Abstract Wild-type p53 is a stress-responsive transcription factor and potent tumor suppressor. P53 activates or represses genes involved in cell cycle progression or apoptosis in order to arrest the cell cycle or induce cell death. Transcription rep
Externí odkaz:
https://doaj.org/article/548002ffbf9941eab072e47643c6dcc6
Publikováno v:
Translational Oncology, Vol 19, Iss , Pp 101386- (2022)
Acetyl-CoA synthetases ACSS1 and ACSS2 promote conversion of acetate to acetyl-CoA for use in lipid synthesis, protein acetylation, and energy production. These enzymes are elevated in some cancers and important for cell survival under hypoxia and nu
Externí odkaz:
https://doaj.org/article/81032cf5b30d4d99a2808b0d8299ac33
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-1 (2022)
Externí odkaz:
https://doaj.org/article/3ecb118cdad0452dad89b2a31ecbc31c
Publikováno v:
Journal of Molecular Cell Biology
Tamoxifen (TAM) is the first-line endocrine therapy for estrogen receptor-positive (ER+) breast cancer (BC). However, acquired resistance occurs in ∼50% cases. Meanwhile, although the PI3K/AKT/mTOR pathway is a viable target for treatment of endocr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dd56a3a7a5dad89080e5e40552304952
http://europepmc.org/articles/PMC8436705
http://europepmc.org/articles/PMC8436705
Autor:
Lei Duan, Sarah Calhoun, Ricardo E. Perez, Virgilia Macias, Fatima Mir, Melissa R. Pergande, Paolo Gattuso, Jeffrey A. Borgia, Carl G. Maki
Publikováno v:
Cancers; Volume 14; Issue 3; Pages: 739
Cancers, Vol 14, Iss 739, p 739 (2022)
Cancers, Vol 14, Iss 739, p 739 (2022)
TNBC is an aggressive cancer sub-type with limited treatment options and poor prognosis. New therapeutic targets are needed to improve outcomes in TNBC patients. PRCP is a lysosomal serine protease that cleaves peptide substrates when the penultimate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2190f2919df1d9083432e147db26233b
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-13 (2022)
Scientific Reports
Scientific Reports
Wild-type p53 is a stress-responsive transcription factor and potent tumor suppressor. P53 activates or represses genes involved in cell cycle progression or apoptosis in order to arrest the cell cycle or induce cell death. Transcription repression b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9e9c4c9f3a17e03c5105291b9361d510
https://pubmed.ncbi.nlm.nih.gov/35296774
https://pubmed.ncbi.nlm.nih.gov/35296774
Publikováno v:
Marine Policy. 74:292-299
Commercial fishing research often focuses on ecological (gear, stock-assessment, traceability) or economic factors or indicators. Truly understanding the social-ecological system requires considering the social, cultural, historical, and legal/policy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d1350d33ae2b199885646575328ab345
https://doi.org/10.1016/j.marpol.2016.04.033
https://doi.org/10.1016/j.marpol.2016.04.033
Autor:
Kevin L. Thomas, Katrina Damon, Bimal R. Shah, Sarah Calhoun, Nancy M. Allen LaPointe, Laine Thomas, Sharon Elliot-Bynum, Kristin D. Thomas, Robert M. Califf, Robin Mathews, Eric D. Peterson
Publikováno v:
Circulation: Cardiovascular Quality and Outcomes. 6:741-748
Background— Despite the widespread availability of effective and affordable therapies, hypertension remains this country’s most significant modifiable cardiovascular risk factor. Approximately 30% to 50% of individuals with hypertension currently
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ea7148d549d1a06087349fd161272b3e
https://doi.org/10.1161/circoutcomes.113.000148
https://doi.org/10.1161/circoutcomes.113.000148
Autor:
W. Schuyler Jones, David Dai, Judith A. Stafford, Sarah Calhoun, Eric D. Peterson, Sumeet Subherwal, Manesh R. Patel
Publikováno v:
Journal of the American College of Cardiology. 60:2230-2236
Objectives This study sought to characterize temporal trends, patient-specific factors, and geographic variation associated with amputation in patients with lower-extremity peripheral artery disease (LE PAD) during the study period. Background Amputa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a15b90d2447477a66bd9dc9c0fbe6759
https://doi.org/10.1016/j.jacc.2012.08.983
https://doi.org/10.1016/j.jacc.2012.08.983
Autor:
Sarah Calhoun, Lara E. Slattery, Shuang Li, Christopher P. Cannon, John S. Rumsfeld, Jennifer Poteat, Barbara L. Lytle, Karen P. Alexander, Tracy Y. Wang, Matthew T. Roe, Eric D. Peterson
Publikováno v:
Circulation: Cardiovascular Quality and Outcomes. 4:129-135
Background— Efforts to improve quality of care for patients with acute myocardial infarction (AMI) are a national priority. To date, there have been few studies that have prospectively evaluated hospital quality improvement (QI) interventions. Meth
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::08739e6a4151f9a38bf5bb0f10fbcd38
https://doi.org/10.1161/circoutcomes.110.958470
https://doi.org/10.1161/circoutcomes.110.958470