Cross-Country Individual Participant Analysis of 4.1 Million Singleton Births in 5 Countries with Very High Human Development Index Confirms Known Associations but Provides No Biologic Explanation for 2/3 of All Preterm Births.

Autor: David M Ferrero, Jim Larson, Bo Jacobsson, Gian Carlo Di Renzo, Jane E Norman, James N Martin, Mary D'Alton, Ernesto Castelazo, Chris P Howson, Verena Sengpiel, Matteo Bottai, Jonathan A Mayo, Gary M Shaw, Ivan Verdenik, Nataša Tul, Petr Velebil, Sarah Cairns-Smith, Hamid Rushwan, Sabaratnam Arulkumaran, Jennifer L Howse, Joe Leigh Simpson

Publikováno v: PLoS ONE, Vol 11, Iss 9, p e0162506 (2016)

BACKGROUND:Preterm birth is the most common single cause of perinatal and infant mortality, affecting 15 million infants worldwide each year with global rates increasing. Understanding of risk factors remains poor, and preventive interventions have o

Externí odkaz: https://doaj.org/article/11dd6ae587304bc69883af641013c26a

Reboot contraceptives research — it has been stuck for decades

Autor: Kirsten M Vogelsong, Sarah G. Chamberlain, Michelle Weinberger, Stephen E. Gerrard, Emily Serazin, Sarah Cairns-Smith

Publikováno v: Nature. 587:543-545

There is a huge global market, and exciting tools are ready to help develop what women want. There is a huge global market, and exciting tools are ready to help develop what women want.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::dc9507e65a70fa1c1d81a141ed2dc956
https://doi.org/10.1038/d41586-020-03287-0

Cross-Country individual participant analysis of 4.1 million singleton births in 5 countries with very high human development index confirms known associations but provides no biologic explanation for 2/3 of all preterm births

Autor: Sabaratnam Arulkumaran, Hamid Rushwan, Verena Sengpiel, Bo Jacobsson, David M. Ferrero, Nataša Tul, Petr Velebil, Jim Larson, Ivan Verdenik, Joe Leigh Simpson, Sarah Cairns-Smith, Mary E. D'Alton, Jane E. Norman, Jonathan A. Mayo, Chris P. Howson, Ernesto Castelazo, Jennifer L. Howse, Gian Carlo Di Renzo, Gary M. Shaw, Matteo Bottai, James N. Martin

Publikováno v: Ferrero, D M, Larson, J, Jacobsson, B, Di Renzo, G C, Norman, J E, Martin, J N, D’alton, M, Castelazo, E, Howson, C P, Sengpiel, V, Bottai, M, Mayo, J A, Shaw, G M, Verdenik, I, Tul, N, Velebil, P, Cairns-smith, S, Rushwan, H, Arulkumaran, S, Howse, J L, Simpson, J L & Luo, Z (ed.) 2016, ' Cross-Country Individual Participant Analysis of 4.1 Million Singleton Births in 5 Countries with Very High Human Development Index Confirms Known Associations but Provides No Biologic Explanation for 2/3 of All Preterm Births ', PLoS ONE, vol. 11, no. 9, pp. e0162506 . https://doi.org/10.1371/journal.pone.0162506
PLoS ONE
PLoS ONE, Vol 11, Iss 9, p e0162506 (2016)

Background Preterm birth is the most common single cause of perinatal and infant mortality, affecting 15 million infants worldwide each year with global rates increasing. Understanding of risk factors remains poor, and preventive interventions have o

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c1f23b95fd99ef3f013361798fc7f424
http://hdl.handle.net/11391/1388332

Regulation of O6-methylguanine-DNA methyltransferase expression in the Burkitt's lymphoma cell line Raji

Autor: Peter Karran, Claire Stephenson, Sarah Cairns-Smith, Peter Macpherson

Publikováno v: Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis. 233:23-30

We have investigated the expression of the DNA-repair enzyme O6-methylguanine-DNA methyltransferase in the Burkitt's lymphoma cell line Raji. An existing mutant Raji cell line which lacks thymidine kinase activity had previously been shown to be Mex-

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::92cab3116e4a8430cd023eb4644b6f44
https://doi.org/10.1016/0027-5107(90)90147-v

Preventing preterm births: analysis of trends and potential reductions with interventions in 39 countries with very high human development index

Autor: Sarah Cairns-Smith, Eve M. Lackritz, Jim Larson, Shoo K. Lee, Catherine Y. Spong, Joe Leigh Simpson, Salimah R. Walani, Christopher P Howson, Joy E Lawn, Hannah H Chang, Hannah Blencowe, Elizabeth Mason, Andrew C Serazin

Publikováno v: The Lancet. (9862):223-234

SummaryBackgroundEvery year, 1·1 million babies die from prematurity, and many survivors are disabled. Worldwide, 15 million babies are born preterm (

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b2d172947b0d1c7f115f4900d7441d48