Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Sarah C. W. Marott"'
Publikováno v:
Cardiovascular research.
Aims Whether high body mass index (BMI) causally influences development and prognosis of heart failure has implications for clinical practice. We tested the hypotheses that high BMI causally influences heart failure incidence and mortality. Methods a
Publikováno v:
The Journal of Clinical Endocrinology & Metabolism. 104:1313-1324
Context Obesity, glucose, insulin resistance [homeostatic model assessment, version 2, for insulin resistance (HOMA2-IR)], and insulin secretion (HOMA2-β) have been associated with type 2 diabetes (T2D) observationally. However, the causal, genetic
Autor:
Børge G. Nordestgaard, Anne Tybjærg-Hansen, Marianne Benn, Sarah C. W. Marott, Frida Emanuelsson
Publikováno v:
Diabetes care. 43(4)
OBJECTIVE To evaluate whether high glucose levels in the normoglycemic range and higher have a causal genetic effect on risk of retinopathy, neuropathy, nephropathy, chronic kidney disease (CKD), peripheral arterial disease (PAD), and myocardial infa
Autor:
Frida Emanuelsson, Marianne Benn, Sarah C. W. Marott, Børge G. Nordestgaard, Anne Tybjærg-Hansen
Publikováno v:
Diabetes. 68
Aim: To investigate the observational and causal associations between glucose levels in the nondiabetic range and risk of vascular diseases in the general population. Methods: We included 112,457 nondiabetic individuals from the Copenhagen City Heart
Publikováno v:
The Journal of Clinical Endocrinology & Metabolism. 101:3212-3221
The metabolic syndrome (MetS) is associated with type 2 diabetes (T2D). However, whether each of the 5 components of the MetS individually is causally associated with T2D is unknown.We tested the hypothesis that each component is causally associated
Publikováno v:
Atherosclerosis. 287:e9
Publikováno v:
European Heart Journal. 35:1205-1214
Aims To examine the associations between antihypertensive treatment with angiotensin-converting enzyme inhibitors (ACEis) or angiotensin receptor blockers (ARBs), β-blockers, diuretics, or calcium-antagonists, and risk of atrial fibrillation. We exa
Autor:
Marianne Benn, Anne Tybjærg-Hansen, Julia S. Johansen, Gorm B. Jensen, Børge G. Nordestgaard, Sarah C. W. Marott
Publikováno v:
International Journal of Cardiology. 167:1354-1359
Atrial fibrillation is associated with inflammation. In contrast to inflammatory markers like C-reactive protein (CRP) and fibrinogen produced in the liver, YKL-40 is produced at the site of inflammation including in the myocardium. We hypothesized t
Publikováno v:
British Journal of Clinical Pharmacology. 76:114-124
Aims Activation of the angiotensin II type 1 (AT1) receptor has been shown to mediate the structural and electrical remodelling of the atrial myocardium associated with atrial fibrillation. We hypothesized that AT1 genotypic variation is associated w
Autor:
Sarah C. W. Marott, Anne Tybjærg-Hansen, Jens Friberg, Jeppe Zacho, Gorm B. Jensen, Marianne Benn, Børge G. Nordestgaard
Publikováno v:
Journal of the American College of Cardiology. 56:789-795
Objectives The purpose of this study was to test whether the association of C-reactive protein (CRP) with increased risk of atrial fibrillation is a robust and perhaps even causal association. Background Elevated levels of CRP previously have been as