Zobrazeno 1 - 10
of 31
pro vyhledávání: '"Sarah C. Van Alsten"'
Autor:
Alina M. Hamilton, Andrea Walens, Sarah C. Van Alsten, Linnea T. Olsson, Joseph Nsonwu-Farley, Xiaohua Gao, Erin L. Kirk, Charles M. Perou, Lisa A. Carey, Melissa A. Troester, Yara Abdou
Publikováno v:
Breast Cancer Research, Vol 26, Iss 1, Pp 1-11 (2024)
Abstract Purpose Survivin/BIRC5 is a proliferation marker that is associated with poor prognosis in breast cancer and an attractive therapeutic target. However, BIRC5 has not been well studied among racially diverse populations where aggressive breas
Externí odkaz:
https://doaj.org/article/27b60ce2e45d4cbb9f8f5a40b8cba4bf
Autor:
Yao Li, Sarah C. Van Alsten, Dong Neuck Lee, Taebin Kim, Benjamin C. Calhoun, Charles M. Perou, Sara E. Wobker, J. S. Marron, Katherine A. Hoadley, Melissa A. Troester
Publikováno v:
Cancers, Vol 16, Iss 13, p 2294 (2024)
High intratumoral heterogeneity is thought to be a poor prognostic indicator. However, the source of heterogeneity may also be important, as genomic heterogeneity is not always reflected in histologic or ‘visual’ heterogeneity. We aimed to develo
Externí odkaz:
https://doaj.org/article/1ee2f7d8908b420996d03d526dbd9a23
Autor:
Markia A. Smith, Sarah C. Van Alsten, Andrea Walens, Jeffrey S. Damrauer, Ugwuji N. Maduekwe, Russell R. Broaddus, Michael I. Love, Melissa A. Troester, Katherine A. Hoadley
Publikováno v:
Cancers, Vol 14, Iss 17, p 4282 (2022)
DNA repair pathways have been associated with variability in hepatocellular carcinoma (HCC) clinical outcomes, but the mechanism through which DNA repair varies as a function of liver regeneration and other HCC characteristics is poorly understood. W
Externí odkaz:
https://doaj.org/article/9f4c81cfbfd740a082e7b38e9252b1de
Autor:
Danielle J. Fassler, Luke A. Torre-Healy, Rajarsi Gupta, Alina M. Hamilton, Soma Kobayashi, Sarah C. Van Alsten, Yuwei Zhang, Tahsin Kurc, Richard A. Moffitt, Melissa A. Troester, Katherine A. Hoadley, Joel Saltz
Publikováno v:
Cancers, Vol 14, Iss 9, p 2148 (2022)
Tumor-infiltrating lymphocytes (TILs) have been established as a robust prognostic biomarker in breast cancer, with emerging utility in predicting treatment response in the adjuvant and neoadjuvant settings. In this study, the role of TILs in predict
Externí odkaz:
https://doaj.org/article/9af9b610ff934defa82bdb1793de86d7
Autor:
Alina M. Hamilton, Sarah C. Van Alsten, Xiaohua Gao, Joseph Nsonwu-Farley, Benjamin C. Calhoun, Michael I. Love, Melissa A. Troester, Katherine A. Hoadley
Publikováno v:
Cancer Research Communications. 3:12-20
Markers of genomic instability, including TP53 status and homologous recombination deficiency (HRD), are candidate biomarkers of immunogenicity and immune-mediated survival, but little is known about the distribution of these markers in large, popula
Autor:
Melissa A. Troester, Katherine A. Hoadley, Cyrus Vaziri, Charles M. Perou, Gaorav P. Gupta, Michael I. Love, Erin L. Kirk, Alina M. Hamilton, Xiaohua Gao, Alex Lockhart, Markia A. Smith, Linnea T. Olsson, Sarah C. Van Alsten, Andrea Walens
Background:Aberrant expression of DNA repair pathways such as homologous recombination (HR) can lead to DNA repair imbalance, genomic instability, and altered chemotherapy response. DNA repair imbalance may predict prognosis, but variation in DNA rep
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::26082be2ddd4e39d8e04cca6b3b9f150
https://doi.org/10.1158/1055-9965.c.6660312.v1
https://doi.org/10.1158/1055-9965.c.6660312.v1
Autor:
Melissa A. Troester, Katherine A. Hoadley, Cyrus Vaziri, Charles M. Perou, Gaorav P. Gupta, Michael I. Love, Erin L. Kirk, Alina M. Hamilton, Xiaohua Gao, Alex Lockhart, Markia A. Smith, Linnea T. Olsson, Sarah C. Van Alsten, Andrea Walens
Supplementary Figure from RNA-Based Classification of Homologous Recombination Deficiency in Racially Diverse Patients with Breast Cancer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::04cd3e65fc8112cd41e42cf4195fbcb1
https://doi.org/10.1158/1055-9965.23099349.v1
https://doi.org/10.1158/1055-9965.23099349.v1
Autor:
Katherine A. Hoadley, Melissa A. Troester, Michael I. Love, Benjamin C. Calhoun, Joseph Nsonwu-Farley, Xiaohua Gao, Sarah C. Van Alsten, Alina M. Hamilton
Supplemental figure 2 displays unadjusted adaptive and innate scores according TP53, HRD and PD-L1 status, stratified by estrogen receptor status.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::07202e40aec25e9ce0b276ba374c175b
https://doi.org/10.1158/2767-9764.22546494
https://doi.org/10.1158/2767-9764.22546494
Autor:
Katherine A. Hoadley, Melissa A. Troester, Michael I. Love, Benjamin C. Calhoun, Joseph Nsonwu-Farley, Xiaohua Gao, Sarah C. Van Alsten, Alina M. Hamilton
Markers of genomic instability, including TP53 status and homologous recombination deficiency (HRD), are candidate biomarkers of immunogenicity and immune-mediated survival, but little is known about the distribution of these markers in large, popula
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::546da8417ccebc5ba6809ee17b04350e
https://doi.org/10.1158/2767-9764.c.6551187
https://doi.org/10.1158/2767-9764.c.6551187
Autor:
Katherine A. Hoadley, Melissa A. Troester, Michael I. Love, Benjamin C. Calhoun, Joseph Nsonwu-Farley, Xiaohua Gao, Sarah C. Van Alsten, Alina M. Hamilton
Supplemental table 3 shows five-year recurrence hazard ratios for immune classes among ER-negative and ER-positive cases in CBCS.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::81421cf796fd511ecb94b6e17ce69a9c
https://doi.org/10.1158/2767-9764.22546485.v1
https://doi.org/10.1158/2767-9764.22546485.v1