Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Sarah C. Styke"'
Autor:
Suzanne D. Conzen, Masha Kocherginsky, Tzintzuni I. Garcia, Kathleen R. Bowie, Sarah C. Styke, Charles F. Pierce, Kyle M. Hernandez, Eva Y. Tonsing-Carter, Deng Pan, Diana C. West
Analyzed gene expression data for GR- and ER-bound genes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::33eb54e1327451758e953d499a188b21
https://doi.org/10.1158/1541-7786.22511244.v1
https://doi.org/10.1158/1541-7786.22511244.v1
Autor:
Suzanne D. Conzen, Masha Kocherginsky, Tzintzuni I. Garcia, Kathleen R. Bowie, Sarah C. Styke, Charles F. Pierce, Kyle M. Hernandez, Eva Y. Tonsing-Carter, Deng Pan, Diana C. West
Analyzed gene expression data for GR-bound genes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5a1ebdcb80b9631a180d21335f0c42b1
https://doi.org/10.1158/1541-7786.22511247
https://doi.org/10.1158/1541-7786.22511247
Autor:
Suzanne D. Conzen, Masha Kocherginsky, Tzintzuni I. Garcia, Kathleen R. Bowie, Sarah C. Styke, Charles F. Pierce, Kyle M. Hernandez, Eva Y. Tonsing-Carter, Deng Pan, Diana C. West
Supplementary Figure 1. ChIP-seq for GR and ER peaks and associated genes and motifs. Supplementary Figure 2. GR immunoprecipitation demonstrates ER interaction. Supplementary Figure 3. Most represented transcription factor response element motifs in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b644693b98b886c4b7fef0acca7c1f48
https://doi.org/10.1158/1541-7786.22511241
https://doi.org/10.1158/1541-7786.22511241
Autor:
Suzanne D. Conzen, Masha Kocherginsky, Tzintzuni I. Garcia, Kathleen R. Bowie, Sarah C. Styke, Charles F. Pierce, Kyle M. Hernandez, Eva Y. Tonsing-Carter, Deng Pan, Diana C. West
Supplementary Information: Supplementary Materials and Methods, Supplementary Methods, Supplementary Figure Legends, and Description of Supplementary Data Files
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::003899c50fd5249f8adc7e3af95916c2
https://doi.org/10.1158/1541-7786.22511238.v1
https://doi.org/10.1158/1541-7786.22511238.v1
Autor:
Suzanne D. Conzen, Balázs Györffy, Gini F. Fleming, Liewei Wang, Krishna R. Kalari, Matthew P. Goetz, Judy C. Boughey, Geoffrey L. Greene, Larischa de Wet, Caroline R. Kim, Sarah C. Styke, Charles F. Pierce, Maxwell N. Skor, Ryan V. Harkless, Kathleen R. Bowie, Kevin J. Thompson, Jason P. Sinnwell, Ricardo R. Lastra, David J. Hosfield, D. Nesli Dolcen, Eva Y. Tonsing-Carter, Masha Kocherginsky, Diana C. West
Purpose: Although high glucocorticoid receptor (GR) expression in early-stage estrogen receptor (ER)-negative breast cancer is associated with shortened relapse-free survival (RFS), how associated GR transcriptional activity contributes to aggressive
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::12e027a72cce381dcf4648a09af62b3f
https://doi.org/10.1158/1078-0432.c.6525818.v1
https://doi.org/10.1158/1078-0432.c.6525818.v1
Autor:
Suzanne D. Conzen, Balázs Györffy, Gini F. Fleming, Liewei Wang, Krishna R. Kalari, Matthew P. Goetz, Judy C. Boughey, Geoffrey L. Greene, Larischa de Wet, Caroline R. Kim, Sarah C. Styke, Charles F. Pierce, Maxwell N. Skor, Ryan V. Harkless, Kathleen R. Bowie, Kevin J. Thompson, Jason P. Sinnwell, Ricardo R. Lastra, David J. Hosfield, D. Nesli Dolcen, Eva Y. Tonsing-Carter, Masha Kocherginsky, Diana C. West
Graphical images of GR ChIP-seq peaks in regions flanking the TSSs of the n=31 GR putative direct target genes contained in the GRsig
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::53b5f65c71a301a35e8499846e2f1e36
https://doi.org/10.1158/1078-0432.22464830
https://doi.org/10.1158/1078-0432.22464830
Autor:
Suzanne D. Conzen, Balázs Györffy, Gini F. Fleming, Liewei Wang, Krishna R. Kalari, Matthew P. Goetz, Judy C. Boughey, Geoffrey L. Greene, Larischa de Wet, Caroline R. Kim, Sarah C. Styke, Charles F. Pierce, Maxwell N. Skor, Ryan V. Harkless, Kathleen R. Bowie, Kevin J. Thompson, Jason P. Sinnwell, Ricardo R. Lastra, David J. Hosfield, D. Nesli Dolcen, Eva Y. Tonsing-Carter, Masha Kocherginsky, Diana C. West
Details about the n=232 putative direct GR targets and Dex GR peaks that are loss, gained, or conserved upon addition of GR antagonists.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::04e61b81e89f6ce67883868a7b956200
https://doi.org/10.1158/1078-0432.22464833.v1
https://doi.org/10.1158/1078-0432.22464833.v1
Autor:
Suzanne D. Conzen, Balázs Györffy, Gini F. Fleming, Liewei Wang, Krishna R. Kalari, Matthew P. Goetz, Judy C. Boughey, Geoffrey L. Greene, Larischa de Wet, Caroline R. Kim, Sarah C. Styke, Charles F. Pierce, Maxwell N. Skor, Ryan V. Harkless, Kathleen R. Bowie, Kevin J. Thompson, Jason P. Sinnwell, Ricardo R. Lastra, David J. Hosfield, D. Nesli Dolcen, Eva Y. Tonsing-Carter, Masha Kocherginsky, Diana C. West
Supplementary Figures, Materials and Methods, and Descriptions of Supplementary files Supplementary Figure 1. Ligand displacement of GC from GR LBD. Supplementary Figure 2. C297 monotherapy is not cytotoxic in vitro or in vivo. Supplementary Figure 3
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::92e48db567b458213296fced45e7f535
https://doi.org/10.1158/1078-0432.22464827
https://doi.org/10.1158/1078-0432.22464827
Autor:
Suzanne D. Conzen, Balázs Györffy, Gini F. Fleming, Liewei Wang, Krishna R. Kalari, Matthew P. Goetz, Judy C. Boughey, Geoffrey L. Greene, Larischa de Wet, Caroline R. Kim, Sarah C. Styke, Charles F. Pierce, Maxwell N. Skor, Ryan V. Harkless, Kathleen R. Bowie, Kevin J. Thompson, Jason P. Sinnwell, Ricardo R. Lastra, David J. Hosfield, D. Nesli Dolcen, Eva Y. Tonsing-Carter, Masha Kocherginsky, Diana C. West
Patient and tumor prognostic values of study cohorts and a flow chart of the study design.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::50dd9d606af620d82f77058e6aa0a0bf
https://doi.org/10.1158/1078-0432.22464836.v1
https://doi.org/10.1158/1078-0432.22464836.v1
Autor:
Kathleen R. Bowie, Kyle M. Hernandez, Deng Pan, Sarah C. Styke, Masha Kocherginsky, Eva Tonsing-Carter, Suzanne D. Conzen, Charles F. Pierce, Tzintzuni Garcia, Diana C. West
Publikováno v:
Molecular Cancer Research. 14:707-719
In estrogen receptor (ER)–negative breast cancer, high tumor glucocorticoid receptor (GR) expression has been associated with a relatively poor outcome. In contrast, using a meta-analysis of several genomic datasets, here we find that tumor GR mRNA
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e4d4b489a5324759371a44036138482f
https://doi.org/10.1158/1541-7786.mcr-15-0433
https://doi.org/10.1158/1541-7786.mcr-15-0433
