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pro vyhledávání: '"Sarah C. Piacente"'
Autor:
Benjamin K. Dickerman, Linda Christen, Edward G. Niles, Mohamed R. Mohamed, Sarah C. Piacente
Publikováno v:
Virology. 376(1):211-224
Vaccinia virus early gene transcription requires the vaccinia termination factor, VTF, nucleoside triphosphate phosphohydrolase I, NPH I, ATP, the virion RNA polymerase, and the motif, UUUUUNU, in the nascent RNA, found within 30 to 50 bases from the
Publikováno v:
Virology. 310(1):109-117
Vaccinia virus nucleoside triphosphate phosphohydrolase I (NPH I) is an essential early gene transcription termination factor. The C-terminal end of NPH I binds to the N-terminal end of the H4L subunit (RAP94) of the virion RNA polymerase. This inter
Autor:
Justin Sibert, Sarah C. Piacente, Eric Alani, Andrew R. Bukata, Jennifer A. Surtees, Jaime O'Connor, Charanya Kumar
Publikováno v:
Journal of molecular biology. 411(4)
DNA mismatch repair (MMR) is a highly conserved mutation avoidance mechanism that corrects DNA polymerase misincorporation errors. In initial steps in MMR, Msh2–Msh6 binds mispairs and small insertion/deletion loops, and Msh2–Msh3 binds larger in
Publikováno v:
Virology. (1):225-235
The vaccinia virus core contains a 195 kb double stranded DNA genome, a multi-subunit RNA polymerase, transcription initiation and termination factors and mRNA processing enzymes. Upon infection, vaccinia virus early gene transcription takes place in
Publikováno v:
Virology. (2):359-370
Prior efforts demonstrated that RNA oligonucleotides containing the transcription termination signal UUUUUNU stimulate premature termination of vaccinia virus early gene transcription, in vitro. This observation suggests that viral transcription term