Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Sarah C. Ogden"'
Autor:
Rebecca A. Buchwalter, Sarah C. Ogden, Sara B. York, Li Sun, Chunfeng Zheng, Christy Hammack, Yichen Cheng, Jieyan V. Chen, Allaura S. Cone, David G. Meckes, Hengli Tang, Timothy L. Megraw
Publikováno v:
Cells, Vol 10, Iss 12, p 3335 (2021)
Zika virus (ZIKV) became a global health concern in 2016 due to its links to congenital microcephaly and other birth defects. Flaviviruses, including ZIKV, reorganize the endoplasmic reticulum (ER) to form a viroplasm, a compartment where virus parti
Externí odkaz:
https://doaj.org/article/303032ca97c04348983879c035ca9e8f
Autor:
Hengli Tang, Christy Hammack, Sara B. York, Yichen Cheng, Rebecca A Buchwalter, Jieyan V. Chen, Li Sun, David G. Meckes, Chunfeng Zheng, Sarah C. Ogden, Allaura S. Cone, Timothy L. Megraw
Publikováno v:
Cells; Volume 10; Issue 12; Pages: 3335
Cells
Cells, Vol 10, Iss 3335, p 3335 (2021)
Cells
Cells, Vol 10, Iss 3335, p 3335 (2021)
Zika virus (ZIKV) became a global health concern in 2016 due to its links to congenital microcephaly and other birth defects. Flaviviruses, including ZIKV, reorganize the endoplasmic reticulum (ER) to form a viroplasm, a compartment where virus parti
Autor:
Allaura S. Cone, David M. Gilbert, Angelica Medina, Hongjun Song, Yuna Son, Hengli Tang, Zhexing Wen, Margo A. Brinton, Guo Li Ming, Joseph C. Madden, Ernest Owen Nicandro Phillips, Sarah C. Ogden, Akash Gunjan, Christy Hammack, Chongchong Xu, Ruth Didier, Serena Giovinazzi
Publikováno v:
Journal of Virology
Zika virus (ZIKV) infection attenuates the growth of human neural progenitor cells (hNPCs). As these hNPCs generate the cortical neurons during early brain development, the ZIKV-mediated growth retardation potentially contributes to the neurodevelopm
Autor:
Denis Avey, Joseph Gillen, Hunter Williams, Amritpal Bahga, Fanxiu Zhu, Sarah Tepper, Wenwei Li, Benjamin Pifer, Sarah C. Ogden
Publikováno v:
Journal of Virology. 90:5953-5964
Kaposi's sarcoma-associated herpesvirus (KSHV) is the causative agent of three human malignancies. KSHV ORF36 encodes a serine/threonine viral protein kinase, which is conserved throughout all herpesviruses. Although several studies have identified t
Autor:
Hengli Tang, Emily M. Lee, Jaehoon Shin, Ruth Didier, Guo Li Ming, Bing Yao, Yujing Li, Xuyu Qian, Hongjun Song, Zhexing Wen, Peng Jin, Christy Hammack, Sarah C. Ogden, Feiran Zhang, Kimberly M. Christian
Publikováno v:
Cell Stem Cell. 18:587-590
SUMMARY The suspected link between infection by Zika virus (ZIKV), a re-emerging flavivirus, and microcephaly is an urgent global health concern. The direct target cells of ZIKV in the developing human fetus are not clear. Here we show that a strain
Autor:
Wenwei Li, Benjamin Pifer, Joseph Gillen, Denis Avey, Hunter Williams, Amritpal Bahga, Sarah Tepper, Fanxiu Zhu, Sarah C. Ogden
Kaposi's sarcoma-associated herpesvirus (KSHV) is the causative agent of three human malignancies. KSHV ORF36 encodes a serine/threonine viral protein kinase, which is conserved throughout all herpesviruses. Although several studies have identified t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bed874c523ee8bc18e6f17c9d09b2956
https://europepmc.org/articles/PMC5686716/
https://europepmc.org/articles/PMC5686716/
Autor:
Zhiqin Wang, Ha Nam Nguyen, Yichen Cheng, Li Chen, Miao Xu, Hengli Tang, Xuyu Qian, Tianlei Xu, Zhexing Wen, Pei Yong Shi, Guo Li Ming, Emily M. Lee, Menghang Xia, Ki Jun Yoon, Kimberly M. Christian, Hao Wu, Wei Zheng, Christy Hammack, Mingjiang Xu, Luoxiu Huang, Feiran Zhang, Sarah C. Ogden, Wei Kai Huang, Chao Shan, Bing Yao, Hongjun Song, Yujing Li, Zhaohui S. Qin, Hao Feng, Peng Jin
Publikováno v:
Nucleic Acids Research
Zika virus (ZIKV) infection causes microcephaly and has been linked to other brain abnormalities. How ZIKV impairs brain development and function is unclear. Here we systematically profiled transcriptomes of human neural progenitor cells exposed to A
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9bff09d1029c618da337e59ef008968e
https://doi.org/10.1101/071183
https://doi.org/10.1101/071183
Autor:
Hengli Tang, Jennifer Kouznetsova, Paul Shinn, Wei Zheng, Wei Kai Huang, Menghang Xia, Miao Xu, Christy Hammack, Julia Tcw, Chase Allen, Xuyu Qian, Alison Goate, Ha Nam Nguyen, Zhexing Wen, Wenwei Huang, Guo Li Ming, Hongjun Song, Samuel G. Michael, Kristen J. Brennand, Sarah C. Ogden, Ruili Huang, Anton Simeonov, Yichen Cheng, Catherine Hanna, Kimberly M. Christian, Fadi Jacob, Misha Itkin, Emily M. Lee
Publikováno v:
Nature Medicine
In response to the current global health emergency posed by the Zika virus (ZIKV) outbreak and its link to microcephaly and other neurological conditions, we performed a drug repurposing screen of ∼6,000 compounds that included approved drugs, clin
Autor:
Yujing Li, Hao Wu, Guo Li Ming, William J. Jeang, Michael Chickering, Li Lin, Sarah C. Ogden, Chun Zhong, Ce Zhang, Gregory R. Hamersky, Bing Yao, Xuyu Qian, Jai Thakor, Zhexing Wen, Cheng-Ying Ho, Hengli Tang, Pei Yong Shi, Brady J. Maher, Fadi Jacob, Christopher Hadiono, Ki Jun Yoon, Peng Jin, Mingxi M. Song, Ha Nam Nguyen, Kimberly M. Christian, Eunchai Kang, Christy Hammack, Hongjun Song, Daniel A. Berg, David W. Nauen
Cerebral organoids, three-dimensional cultures that model organogenesis, provide a new platform to investigate human brain development. High cost, variability, and tissue heterogeneity limit their broad applications. Here, we developed a miniaturized
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::26d3888e69ba75172517e12e1b2a2d1f
https://europepmc.org/articles/PMC4900885/
https://europepmc.org/articles/PMC4900885/
Autor:
Minghua Zhu, Weiguo Zhang, Jianwei Zou, Sarah A. O’Brien, Yao Zhang, Tieshi Li, Sarah C. Ogden
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 195(9)
Phospholipase D (PLD) proteins are enzymes that catalyze the hydrolysis of phosphatidylcholine to generate an important signaling lipid, phosphatidic acid. Phosphatidic acid is a putative second messenger implicated in the regulation of vesicular tra