Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Sarah C. Garrett"'
Autor:
Nicholas C. Morano, Roshelle S. Smith, Victor Danelon, Ryan Schreiner, Uttsav Patel, Natalia G. Herrera, Carla Smith, Steven M. Olson, Michelle K. Laerke, Alev Celikgil, Scott J. Garforth, Sarah C. Garrett-Thomson, Francis S. Lee, Barbara L. Hempstead, Steven C. Almo
Publikováno v:
The Journal of Clinical Investigation, Vol 132, Iss 22 (2022)
Cell surface receptors, ligands, and adhesion molecules underlie development, circuit formation, and synaptic function of the central nervous system and represent important therapeutic targets for many neuropathologies. The functional contributions o
Externí odkaz:
https://doaj.org/article/62d978590f1d48d48cbcde540b76679b
Autor:
Natalia G. Herrera, Nicholas C. Morano, Alev Celikgil, George I. Georgiev, Ryan J. Malonis, James H. Lee, Karen Tong, Olivia Vergnolle, Aldo B. Massimi, Laura Y. Yen, Alex J. Noble, Mykhailo Kopylov, Jeffrey B. Bonanno, Sarah C. Garrett-Thomson, David B. Hayes, Robert H. Bortz, Ariel S. Wirchnianski, Catalina Florez, Ethan Laudermilch, Denise Haslwanter, J. Maximilian Fels, M. Eugenia Dieterle, Rohit K. Jangra, Jason Barnhill, Amanda Mengotto, Duncan Kimmel, Johanna P. Daily, Liise-anne Pirofski, Kartik Chandran, Michael Brenowitz, Scott J. Garforth, Edward T. Eng, Jonathan R. Lai, Steven C. Almo
Publikováno v:
ACS Omega, Vol 6, Iss 1, Pp 85-102 (2020)
Externí odkaz:
https://doaj.org/article/8225fcf771154e9c93f8122d956b1bc4
Autor:
Hyungjun Jeon, Vladimir Vigdorovich, Sarah C. Garrett-Thomson, Murali Janakiram, Udupi A. Ramagopal, Yael M. Abadi, Jun Sik Lee, Lisa Scandiuzzi, Kim C. Ohaegbulam, Jordan M. Chinai, Ruihua Zhao, Yu Yao, Ying Mao, Joseph A. Sparano, Steven C. Almo, Xingxing Zang
Publikováno v:
Cell Reports, Vol 9, Iss 3, Pp 1089-1098 (2014)
B7x (B7-H4 or B7S1) is a member of the B7 family that can inhibit T cell function. B7x protein is absent in most normal human tissues and immune cells, but it is overexpressed in human cancers and often correlates with negative clinical outcome. The
Externí odkaz:
https://doaj.org/article/2e6a6daa6cf14cbca114e32921f5a907
Publikováno v:
Nature Reviews Drug Discovery. 21:509-528
Publikováno v:
Current Research in Structural Biology, Vol 3, Iss, Pp 337-345 (2021)
Current Research in Structural Biology
Current Research in Structural Biology
Molecular interactions mediated by engagement of the Herpes virus entry mediator (HVEM) with members of TNF and Ig superfamily generate distinct signals in T cell activation pathways that modulate inflammatory and inhibitory responses. HVEM interacts
Autor:
Nicholas C. Morano, Roshelle S. Smith, Victor Danelon, Ryan Schreiner, Uttsav Patel, Natalia G. Herrera, Carla Smith, Steven M. Olson, Michelle K. Laerke, Alev Celikgil, Scott J. Garforth, Sarah C. Garrett-Thomson, Francis S. Lee, Barbara L. Hempstead, Steven C. Almo
Publikováno v:
The Journal of clinical investigation. 132(22)
Cell surface receptors, ligands, and adhesion molecules underlie development, circuit formation, and synaptic function of the central nervous system and represent important therapeutic targets for many neuropathologies. The functional contributions o
Autor:
Udupi A. Ramagopal, Mitchell Kronenberg, Scott J. Garforth, Ting-Fang Chou, Kiyokazu Kakugawa, Kenneth Kim, Steven C. Almo, Elena V. Fedorov, Hilde Cheroutre, Sarah C. Garrett-Thomson, Goo-Young Seo, Jeffrey B. Bonanno, Qingyang Wang, Weifeng Liu
Publikováno v:
The Journal of Experimental Medicine
HVEM is a TNF family receptor that binds a TNF protein and Ig family proteins. Using structural biology and mutagenesis, we identified HVEM muteins with selective ligand binding. We verified their function in vivo in models of inflammation and infect
Autor:
Kiyokazu Kakugawa, Weifeng Liu, Elena V. Fedorov, Hilde Cheroutre, Goo-Young Seo, Jeffrey B. Bonanno, Ting-Fang Chou, Sarah C. Garrett-Thomson, Steven C. Almo, Udupi A. Ramagopa, Mitchell Kronenberg
HVEM is a TNF (tumor necrosis factor) receptor contributing to a broad range of immune functions involving diverse cell types. It interacts with a TNF ligand, LIGHT, and immunoglobulin (Ig) superfamily members BTLA and CD160. Assessing the functional
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4dea66bf858bcc04c09fdb3c6f999ee5
https://doi.org/10.1101/2021.06.16.448617
https://doi.org/10.1101/2021.06.16.448617
Autor:
Ting-Fang Chou, Weifeng Liu, Sarah C. Garrett-Thomson, Goo-Young Seo, Elena Fedorov, Udupi A. Ramagopal, Jeffrey B. Bonanno, Qingyang Wang, Kenneth Kim, Scott J. Garforth, Kiyokazu Kakugawa, Hilde Cheroutre, Mitchell Kronenberg, Steven C. Almo
Publikováno v:
The Journal of Immunology. 208:52.17-52.17
HVEM is a TNF (tumor necrosis factor) receptor contributing to a broad range of immune functions involving diverse cell types. It interacts with a TNF ligand, LIGHT, and immunoglobulin (Ig) superfamily members BTLA and CD160. Assessing the functional
Publikováno v:
Nature Reviews Drug Discovery. 21:163-163