Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Sarah C. Ferrante"'
Autor:
Matthew D. Barberio, Lora J. Kasselman, Martin P. Playford, Samuel B. Epstein, Heather A. Renna, Madeleine Goldberg, Joshua DeLeon, Iryna Voloshyna, Ashley Barlev, Michael Salama, Sarah C. Ferrante, Evan P. Nadler, Nehal Mehta, Allison B. Reiss, Robert J. Freishtat
Publikováno v:
Journal of Translational Medicine, Vol 17, Iss 1, Pp 1-11 (2019)
Abstract Background Macrophage cholesterol efflux capacity has been identified as a predictor for cardiovascular disease. We assessed the relationship between adipocyte-derived extracellular vesicle microRNAs and macrophage cholesterol efflux capacit
Externí odkaz:
https://doaj.org/article/6ce9fff893f94d6cabc9fd6ead0dd0b4
Autor:
Sarah E. Alcala, Ethan L. Matz, John F. Engelhardt, Furquan Shaheen, Jennifer L. Ingram, Claire E. Hoptay, Robert J. Freishtat, Tillie-Louise Hackett, Yulong Zhang, Dinesh K. Pillai, Sarah C. Ferrante
Publikováno v:
American Journal of Respiratory Cell and Molecular Biology. 56:291-299
Limited in vivo models exist to investigate the lung airway epithelial role in repair, regeneration, and pathology of chronic lung diseases. Herein, we introduce a novel animal model in asthma-a xenograft system integrating a differentiating human as
Autor:
Ashley Barlev, Matthew D. Barberio, Allison B. Reiss, Samuel B. Epstein, Martin P. Playford, Nehal N. Mehta, Heather A. Renna, Iryna Voloshyna, Lora J. Kasselman, Joshua DeLeon, Robert J. Freishtat, Sarah C. Ferrante, Evan P. Nadler, Michael Salama, Madeleine Goldberg
Publikováno v:
Journal of Translational Medicine
Journal of Translational Medicine, Vol 17, Iss 1, Pp 1-11 (2019)
Journal of Translational Medicine, Vol 17, Iss 1, Pp 1-11 (2019)
Background Macrophage cholesterol efflux capacity has been identified as a predictor for cardiovascular disease. We assessed the relationship between adipocyte-derived extracellular vesicle microRNAs and macrophage cholesterol efflux capacity. Method
Autor:
Justin Wang, Evan P. Nadler, Robert J. Freishtat, Walter J. Pories, G. Lynis Dohm, Jung-Hyuk Suh, Sarah C. Ferrante, Matthew D. Barberio, Michelle Mietus-Snyder, Monica J. Hubal
Publikováno v:
Obesity. 25:102-110
Objective Exosomes from obese adipose contain dysregulated microRNAs linked to insulin signaling, as compared with lean controls, providing a direct connection between adiposity and insulin resistance. This study tested the hypotheses that gastric by
Autor:
Monica J. Hubal, Sarah C. Ferrante, Evan P. Nadler, Robert J. Freishtat, Emily S. Koeck, Tatiana Iordanskaia, Samantha Sevilla
Publikováno v:
Journal of Surgical Research. 192:268-275
Background The pathogenesis of nonalcoholic fatty liver disease (NAFLD) has been attributed to increased systemic inflammation and insulin resistance mediated by visceral adipose tissue (VAT), although the exact mechanisms are undefined. Exosomes are
Autor:
Krishna Pancham, Sarah C. Ferrante, Gustavo Nino, Diego Preciado, Mamta Giri, Mary C. Rose, Robert J. Freishtat, Dinesh K. Pillai, Geovanny F. Perez, Stéphanie Val, Jose L. Gomez, Maria J. Gutierrez
Publikováno v:
PLoS ONE
PLoS ONE, Vol 11, Iss 9, p e0162244 (2016)
PLoS ONE, Vol 11, Iss 9, p e0162244 (2016)
Background Innate immune responses are fine-tuned by small noncoding RNA molecules termed microRNAs (miRs) that modify gene expression in response to the environment. During acute infections, miRs can be secreted in extracellular vesicles (EV) to fac
Autor:
Monica J, Hubal, Evan P, Nadler, Sarah C, Ferrante, Matthew D, Barberio, Jung-Hyuk, Suh, Justin, Wang, G Lynis, Dohm, Walter J, Pories, Michelle, Mietus-Snyder, Robert J, Freishtat
Publikováno v:
Obesity (Silver Spring, Md.). 25(1)
Exosomes from obese adipose contain dysregulated microRNAs linked to insulin signaling, as compared with lean controls, providing a direct connection between adiposity and insulin resistance. This study tested the hypotheses that gastric bypass surge
Autor:
John F. Engelhardt, Sarah E. Alcala, Furquan Shaheen, Dinesh K. Pillai, Yulong Zhang, Jennifer L. Ingram, E Matz, Sarah C. Ferrante, Tillie-Louise Hackett, Claire E. Hoptay, Robert J. Freishtat
Publikováno v:
Journal of Investigative Medicine. 64:802-803
Purpose of Study Limited models exist to investigate the airway epithelium9s role in repair, regeneration, and pathology of chronic obstructive lung diseases. We introduce a human asthmatic airway epithelial xenograft system integrating a proliferati
Autor:
Monica J. Hubal, Evan P. Nadler, Heather Gordish-Dressman, Sarah C. Ferrante, Emily S. Koeck, Samantha Sevilla, Justin Wang, Dinesh K. Pillai, Andrew A. Wiles, Zuyi Wang, Robert J. Freishtat
Publikováno v:
Pediatric research
Background Obesity is frequently complicated by comorbid conditions, yet how excess adipose contributes is poorly understood. Although adipocytes in obese individuals induce systemic inflammation via secreted cytokines, another potential mediator has
Autor:
Nicolle Siegart, Michael Salama, Allison B. Reiss, Iryna Voloshyna, Ashley Barlev, Robert J. Freishtat, Joshua DeLeon, Lora J. Kasselman, Michael Littlefield, Sarah C. Ferrante
Publikováno v:
Journal of the American College of Cardiology. 67:2258
Obesity, a major risk for atherosclerotic cardiovascular disease, has quadrupled in adolescents in the last 30 years. How adipose tissue influences the pathological process of atherosclerosis is not well understood. This study compares cholesterol ef