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of 4
pro vyhledávání: '"Sarah C. Bellfy"'
Publikováno v:
The Journal of Immunology. 178:5227-5236
Studies of costimulatory receptors belonging to the TNFR family have revealed their diverse roles in affecting different stages of the T cell response. The 4-1BB ligand (4-1BBL)/4-1BB pathway has emerged as a receptor-ligand pair that impacts not the
Autor:
Sarah C. Bellfy, Edward J. Usherwood, Shinichiro Fuse, Joshua J. Obar, Weijun Zhang, Erica K. Leung
Publikováno v:
Journal of Virology. 80:9159-9170
The interactions between CD80 and CD86 on antigen-presenting cells and CD28 on T cells serve as an important costimulatory signal in the activation of T cells. Although the simplistic two-signal hypothesis has been challenged in recent years by the i
Publikováno v:
European Journal of Immunology. 35:2956-2961
Numerous studies have shown that NK cells are important in controlling the early stages of infection with alpha- or betaherpesviruses. In contrast, little is known about the impact of NK cells on gammaherpesvirus infections. We tested mice with defec
Publikováno v:
Journal of virology. 80(17)
In herpesvirus infections, the virus persists for life but is contained through T-cell-mediated immune surveillance. How this immune surveillance operates is poorly understood. Recent studies of other persistent infections have indicated that virus p