Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Sarah C Moody"'
Autor:
Simon T. Bond, Emily J. King, Darren C. Henstridge, Adrian Tran, Sarah C. Moody, Christine Yang, Yingying Liu, Natalie A. Mellett, Artika P. Nath, Michael Inouye, Elizabeth J. Tarling, Thomas Q. de Aguiar Vallim, Peter J. Meikle, Anna C. Calkin, Brian G. Drew
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-13 (2021)
The genetic determinants of sex-specific differences in obesity are still incompletely understood. Here, the authors demonstrate that adipocyte specific loss of Trim28 in committed adipocytes leads to sex specific differences in the development of ob
Externí odkaz:
https://doaj.org/article/153ba01f3e9e4f4784fc02d6c030c7c9
Publikováno v:
Frontiers in Endocrinology, Vol 13 (2022)
Activin A, a TGFβ superfamily member, is important for normal testis development through its actions on Sertoli cell development. Our analyses of altered activin A mouse models indicated gonocyte abnormalities, implicating activin A as a key determi
Externí odkaz:
https://doaj.org/article/1cca202fbcd24948b73ee09bf267d8a9
Autor:
Aowen Zhuang, Anna C. Calkin, Shannen Lau, Helen Kiriazis, Daniel G. Donner, Yingying Liu, Simon T. Bond, Sarah C. Moody, Eleanor A.M. Gould, Timothy D. Colgan, Sergio Ruiz Carmona, Michael Inouye, Thomas Q. de Aguiar Vallim, Elizabeth J. Tarling, Gregory A. Quaife-Ryan, James E. Hudson, Enzo R. Porrello, Paul Gregorevic, Xiao-Ming Gao, Xiao-Jun Du, Julie R. McMullen, Brian G. Drew
Publikováno v:
iScience, Vol 24, Iss 6, Pp 102537- (2021)
Summary: Long non-coding RNAs (lncRNAs) have been demonstrated to influence numerous biological processes, being strongly implicated in the maintenance and physiological function of various tissues including the heart. The lncRNA OIP5-AS1 (1700020I14
Externí odkaz:
https://doaj.org/article/453eb2947cf84c34a110e74e3feab67a
Autor:
Anna M. D. Watson, Eleanor A. M. Gould, Sarah C. Moody, Priyadharshini Sivakumaran, Karly C. Sourris, Bryna S. M. Chow, Audrey Koïtka-Weber, Terri J. Allen, Karin A. M. Jandeleit-Dahm, Mark E. Cooper, Anna C. Calkin
Publikováno v:
Frontiers in Physiology, Vol 11 (2020)
It is well established that diabetes is the major cause of chronic kidney disease worldwide. Both hyperglycemia, and more recently, advanced glycation endproducts, have been shown to play critical roles in the development of kidney disease. Moreover,
Externí odkaz:
https://doaj.org/article/73fcf4a9c4324f12af7fc95a222337db
Autor:
Samira Hosseini, Sarah C. Moody, Daniela Fietz, Sivanjah Indumathy, Hans-Christian Schuppe, Mark P. Hedger, Kate L. Loveland
Fetal testis growth involves cell influx and extensive remodeling. Immediately after sex determination in mouse, macrophages enable normal cord formation and removal of inappropriately positioned cells. This study provides new information about macro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b0fd938b887e8e946d33855f497a0bb0
https://doi.org/10.21203/rs.3.rs-1507447/v1
https://doi.org/10.21203/rs.3.rs-1507447/v1
The E3 ligase MARCH5 is a PPARγ target gene that regulates mitochondria and metabolism in adipocytes
Autor:
Aldons J. Lusis, Simon T. Bond, Darren C. Henstridge, Bronwyn A. Kingwell, Sarah C. Moody, Yingying Liu, Andrea L. Hevener, Brian G. Drew, Anna C. Calkin, Paul Gregorevic, Mete Civelek, Claudio J. Villanueva
Publikováno v:
American Journal of Physiology-Endocrinology and Metabolism. 316:E293-E304
Mitochondrial dynamics refers to the constant remodeling of mitochondrial populations by multiple cellular pathways that help maintain mitochondrial health and function. Disruptions in mitochondrial dynamics often lead to mitochondrial dysfunction, w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a12a5e7da4da344b190a6a347ffa3be1
https://doi.org/10.1152/ajpendo.00394.2018
https://doi.org/10.1152/ajpendo.00394.2018
Autor:
Julie R. McMullen, T. Q. de Aguiar Vallim, James E. Hudson, Aowen Zhuang, S. Lau, Elizabeth J. Tarling, Paul Gregorevic, Sarah C. Moody, Sergio Ruiz-Carmona, D. Donner, Xiao-Jun Du, Eleanor A.M. Gould, Yingying Liu, Xiao-Ming Gao, Helen Kiriazis, Brian G. Drew, Simon T. Bond, Gregory A. Quaife-Ryan, Michael Inouye, Enzo R. Porrello, Anna C. Calkin, Timothy D. Colgan
BackgroundLong ncRNAs (lncRNAs) are known to influence numerous biological processes including cellular differentiation and tissue development. They are also implicated in the maintenance, health and physiological function of many tissues including t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d82d99545dada077f468b6e9fb245d39
https://doi.org/10.1101/2021.01.28.428540
https://doi.org/10.1101/2021.01.28.428540
Autor:
Adrian Tran, Artika P. Nath, Sarah C. Moody, Darren C. Henstridge, Christine Yang, Michael Inouye, Thomas Q. de Aguiar Vallim, Elizabeth J. Tarling, Brian G. Drew, Simon T. Bond, Yingying Liu, E. King, Natalie A. Mellett, Peter J. Meikle, Anna C. Calkin
Publikováno v:
Nature Communications
Nature Communications, Vol 12, Iss 1, Pp 1-13 (2021)
Nature Communications, Vol 12, Iss 1, Pp 1-13 (2021)
The effective storage of lipids in white adipose tissue (WAT) critically impacts whole body energy homeostasis. Many genes have been implicated in WAT lipid metabolism, including tripartite motif containing 28 (Trim28), a gene proposed to primarily i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::784e2d9bef8833ea989b6eeccecd7963
https://www.repository.cam.ac.uk/handle/1810/315660
https://www.repository.cam.ac.uk/handle/1810/315660
Autor:
Terri J. Allen, Priyadharshini Sivakumaran, Karly C. Sourris, Sarah C. Moody, Audrey Koïtka-Weber, Anna C. Calkin, Bryna S.M. Chow, Anna M. D. Watson, Karin Jandeleit-Dahm, Eleanor A.M. Gould, Mark E. Cooper
Publikováno v:
Frontiers in Physiology
Frontiers in Physiology, Vol 11 (2020)
Frontiers in Physiology, Vol 11 (2020)
It is well established that diabetes is the major cause of chronic kidney disease worldwide. Both hyperglycemia, and more recently, advanced glycation endproducts, have been shown to play critical roles in the development of kidney disease. Moreover,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::acc4b8c45da68e488070bb1f57a937f2
Autor:
Kate L Loveland, Sarah C Moody, Julia C. Young, Patrick S Western, David J. Handelsman, Elizabeth A. Richards, Kristian Almstrup, Liza O'Donnell, Penny A. F. Whiley
Publikováno v:
Endocrinology. 161
Activin A promotes fetal mouse testis development, including driving Sertoli cell proliferation and cord morphogenesis, but its mechanisms of action are undefined. We performed ribonucleic acid sequencing (RNA-seq) on testicular somatic cells from fe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fc52f2239b80a450aaad80613a032c42
https://doi.org/10.1210/endocr/bqaa058
https://doi.org/10.1210/endocr/bqaa058