Zobrazeno 1 - 10
of 31
pro vyhledávání: '"Sarah Blutt"'
Autor:
Anubama Rajan, Ashley Morgan Weaver, Gina Marie Aloisio, Joseph Jelinski, Hannah L. Johnson, Susan F. Venable, Trevor McBride, Letisha Aideyan, Felipe-Andrés Piedra, Xunyan Ye, Ernestina Melicoff-Portillo, Malli Rama Kanthi Yerramilli, Xi-Lei Zeng, Michael A. Mancini, Fabio Stossi, Anthony W. Maresso, Shalaka A. Kotkar, Mary K. Estes, Sarah Blutt, Vasanthi Avadhanula, Pedro A. Piedra
Publikováno v:
mBio, Vol 13, Iss 1 (2022)
ABSTRACT There is an unmet need for preclinical models to understand the pathogenesis of human respiratory viruses and predict responsiveness to immunotherapies. Airway organoids can serve as an ex vivo human airway model to study respiratory viral p
Externí odkaz:
https://doaj.org/article/d19e06d3907d4ae0a97b769078363018
Autor:
Julie In, Jennifer Foulke-Abel, Nicholas C. Zachos, Anne-Marie Hansen, James B. Kaper, Harris D. Bernstein, Marc Halushka, Sarah Blutt, Mary K. Estes, Mark Donowitz, Olga Kovbasnjuk
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology, Vol 2, Iss 1, Pp 48-62.e3 (2016)
Background & Aims: Enterohemorrhagic Escherichia coli (EHEC) causes over 70,000 episodes of foodborne diarrhea annually in the United States. The early sequence of events that precede life-threatening hemorrhagic colitis and hemolytic uremic syndrome
Externí odkaz:
https://doaj.org/article/87059b703a394dd8ad9dc636045067e5
Autor:
David Castillo-Azofeifa, Tomas Wald, Efren A. Reyes, Aaron Gallagher, Julia Schanin, Stephanie Vlachos, Nathalie Lamarche-Vane, Carolyn Bomidi, Sarah Blutt, Mary K. Estes, Todd Nystul, Ophir D. Klein
Publikováno v:
Cell Stem Cell. 30:188-206.e6
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3d9e36ce879ef5bfcca778523f6badef
https://doi.org/10.1016/j.stem.2022.12.008
https://doi.org/10.1016/j.stem.2022.12.008
Autor:
Wantong Yao, Carol Lim, Baoli Hu, Avnish Kapoor, Gerald C. Chu, Mao Xizeng, Chia Chin Wu, Sarah blutt, Di Zhao, Lynda Chin, Sujun Hua, Pingping Hou, Prasenjit Dey, Eduardo Vilar, Michael McArthur, Ronald A. DePinho, Guocan Wang, Deepavali Chakravarti, Denise J. Spring, Christopher Logothesis, Xin Lu, Hongai Xia, Haoqiang Ying, Alan Wang, Pingna Deng
Publikováno v:
Molecular Cancer Research. 18:IA24-IA24
Many common instigators drive the processes of inflammation and carcinogenesis. We have found such a common node in Yap1. In the context of cancer, YAP-TEAD complex is important in modulating the immune microenvironment, such that Yap 1-mediated tran
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5941b558e1891f8ad757cd8ab6386034
https://doi.org/10.1158/1557-3125.hippo19-ia24
https://doi.org/10.1158/1557-3125.hippo19-ia24
Autor:
Alan Wang, Asha S. Multani, Guocan Wang, Sarah blutt, Mao Xizeng, Wenting Liao, Jianhua Zhang, Di Zhao, Denise J. Spring, Ronald A. DePinho, Deepavali Chakravarti, Prasenjit Dey, Kyle Chang, Pablo C. Okhuysen, Mary K. Estes, Christoper Terranova, Baoli Hu, Eduardo Vilar, Pingping Hou
Publikováno v:
Cancer Research. 79:LB-290
The molecular instigators and therapeutic strategies for inflammatory bowel disease (IBD) are limited. Here, telomere dysfunction is shown to activate pAtm/c-Abl-mediated phosphorylation and stabilization of Yap1 up-regulates pro-IL-18 expression, a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c78279bf2e640aacc02705c688bc7807
https://doi.org/10.1158/1538-7445.am2019-lb-290
https://doi.org/10.1158/1538-7445.am2019-lb-290
Autor:
Lawrence Vernetti, Albert Gough, Nicholas Baetz, Sarah Blutt, James R. Broughman, Jacquelyn A. Brown, Jennifer Foulke-Abel, Nesrin Hasan, Julie In, Edward Kelly, Olga Kovbasnjuk, Jonathan Repper, Nina Senutovitch, Janet Stabb, Catherine Yeung, Nick C. Zachos, Mark Donowitz, Mary Estes, Jonathan Himmelfarb, George Truskey, John P. Wikswo, D. Lansing Taylor
Publikováno v:
Scientific Reports
Organ interactions resulting from drug, metabolite or xenobiotic transport between organs are key components of human metabolism that impact therapeutic action and toxic side effects. Preclinical animal testing often fails to predict adverse outcomes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9848c05dacac40ce60c776f71e8b26cb
https://pubmed.ncbi.nlm.nih.gov/28300206
https://pubmed.ncbi.nlm.nih.gov/28300206
Autor:
Julie, In, Jennifer, Foulke-Abel, Nicholas C, Zachos, Anne-Marie, Hansen, James B, Kaper, Harris D, Bernstein, Marc, Halushka, Sarah, Blutt, Mary K, Estes, Mark, Donowitz, Olga, Kovbasnjuk
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology
Background & Aims Enterohemorrhagic Escherichia coli (EHEC) causes over 70,000 episodes of foodborne diarrhea annually in the United States. The early sequence of events that precede life-threatening hemorrhagic colitis and hemolytic uremic syndrome
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::c0e5685af03f292a9e12e25da8abe7e1
https://pubmed.ncbi.nlm.nih.gov/26855967
https://pubmed.ncbi.nlm.nih.gov/26855967
Publikováno v:
The Journal of Immunology. 184:137.22-137.22
Regulatory T cells (Tregs) play an important role in suppression of effector T cell function and inflammation. Recently Tregs have been shown to play a role in mucosal IgA production through production of TGF-β1, suggesting they also can induce B ce
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3420e061336941bdb5e4daad0e1d2652
https://doi.org/10.4049/jimmunol.184.supp.137.22
https://doi.org/10.4049/jimmunol.184.supp.137.22
Autor:
Sarah Blutt, Margaret Conner
Publikováno v:
The Journal of Immunology. 184:38.13-38.13
Many acute viral infections induce early T cell independent polyclonal B cell activation and production of antigen-specific antibody prior to the formation of classical germinal centers. Rotavirus, a well characterized intestinal virus, induces Peyer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a24cbaeeafda3c4c4615ed85a258bb58
https://doi.org/10.4049/jimmunol.184.supp.38.13
https://doi.org/10.4049/jimmunol.184.supp.38.13
Publikováno v:
Gut Microbes; Dec2023, Vol. 15 Issue 2, p1-21, 21p