Astrocytes and Microglia Are Resistant to NAD+-Mediated Cell Death Along the ARTC2/P2X7 Axis

Autor: Björn Rissiek, Joschi Stabernack, Maike Cordes, Yinghui Duan, Sarah Behr, Stephan Menzel, Tim Magnus, Friedrich Koch-Nolte

Publikováno v: Frontiers in Molecular Neuroscience, Vol 12 (2020)

ADP-ribosylation of the P2X7k splice variant on mouse T cells by Ecto-ADP-ribosyltransferase ARTC2.2 in response to its substrate extracellular nicotinamide adenine dinucleotide (NAD+) triggers cell death. Since NAD+ is released as a danger signal du

Externí odkaz: https://doaj.org/article/b828aac893134cff8c5a9f21ed17b0f1

Abstract 2800: Pharmacokinetics, bioavailability, and pharmacodynamics of oral triapine

Autor: Jan H. Beumer, Sarah Behr, Holly Gallion, John Vargo, Frederick Ueland, Haider Mahdi, Brian Orr, Eugenia Girda, Susan Christner, Edward Chu, Charles Kunos, Percy S. Ivy, Sarah Taylor

Publikováno v: Cancer Research. 83:2800-2800

Background: Locally advanced cervical cancer accounts for most deaths from disease. Standard of care includes treatment with cisplatin-based chemoradiation with a 70% response rate. The addition of intravenous (IV) triapine to chemoradiation has show

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::db5e2c5073a0d3f1f76030167064dc85
https://doi.org/10.1158/1538-7445.am2023-2800

Mit Maria und Jesus in den Islamischen Religionsunterricht – Theologische und pädagogische Erörterung, Quellen und Material

Autor: Hamida Sarah Behr

Publikováno v: Edition Fachdidaktiken ISBN: 9783658267193

Maria und Jesus bieten viel Stoff fur den Islamischen Religionsunterricht im westlichen, gegenwartigen Kontext: Maria ist die zentrale Frau im Koran und Jesus der wichtigste Prophet der Christen. Mittels Koranversen und Kommentaren werden die Erzahlu

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::e7c5f3b33f62cbcc7ad89ef1c2f5ce28
https://doi.org/10.1007/978-3-658-26720-9_7

Ecto-ADP-ribosyltransferase ARTC2.1 functionally modulates FcγR1 and FcγR2B on murine microglia

Autor: Maike Cordes, Sarah Behr, Björn Rissiek, Mario Leutert, Anne Rissiek, Sahil Adriouch, Larissa Jank, Stephan Menzel, Peter Ludewig, Friedrich Haag, Michael O. Hottiger, Friedrich Koch-Nolte, Tim Magnus, Mathias Gelderblom

Publikováno v: Scientific Reports
Scientific Reports, Nature Publishing Group, 2017, 7 (1), ⟨10.1038/s41598-017-16613-w⟩
Scientific Reports, Vol 7, Iss 1, Pp 1-13 (2017)

Mammalian ecto-ADP-ribosyltransferases (ecto-ARTs or also ARTCs) catalyze the ADP-ribosylation of cell surface proteins using extracellular nicotinamide adenine dinucleotide (NAD+) as substrate. By this post-translational protein modification, ecto-A

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ca64a325ac9d6e3685a189046eafa295
https://hal-normandie-univ.archives-ouvertes.fr/hal-02375773

Sex, Lies & Money.

Autor: TEPPER, TAYLOR

Publikováno v: Newsweek Global. 3/6/2020, Vol. 174 Issue 6, p10-13. 4p. 2 Color Photographs.