Cannabinoid type-1 receptor signaling in dopaminergic Engrailed-1 expressing neurons modulates motivation and depressive-like behavior

Autor: Sarah Baddenhausen, Beat Lutz, Clementine Hofmann

Publikováno v: Frontiers in Molecular Neuroscience, Vol 17 (2024)

The endocannabinoid system comprises highly versatile signaling functions within the nervous system. It is reported to modulate the release of several neurotransmitters, consequently affecting the activity of neuronal circuits. Investigations have hi

Externí odkaz: https://doaj.org/article/92230dc93f38410aa7ae1963d141e289

A specific prelimbic-nucleus accumbens pathway controls resilience versus vulnerability to food addiction

Autor: Elena Martín-García, Sarah Baddenhausen, Susanne Gerber, Clementine Hofmann, Eric Senabre, Eduardo Domínguez, Irene Serra, Raül Andero, Inigo Ruiz de Azua, Laura Domingo-Rodriguez, Sami Kummer, Rafael Maldonado, Marta Navarrete, Mohit Navandar, Beat Lutz, Mara Dierssen

Publikováno v: Nature Communications, 11(1):782
Nature Communications, Vol 11, Iss 1, Pp 1-16 (2020)
Nature Communications
Dipòsit Digital de Documents de la UAB
Universitat Autònoma de Barcelona
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Food addiction is linked to obesity and eating disorders and is characterized by a loss of behavioral control and compulsive food intake. Here, using a food addiction mouse model, we report that the lack of cannabinoid type-1 receptor in dorsal telen

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4b5b0ca21e6ec730893a6c612286e8ad
https://repository.publisso.de/resource/frl:6422242