Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Sarah Bachmann"'
Autor:
Jane Hübertz Frederiksen, Ulf Birkedal, Sarah Bachmann, Elisabeth Victoria Eliesen, Lene Juel Rasmussen, Katja Venborg Pedersen, Lana Al‐Zehhawi, Susanne E. Boonen, Lotte Krogh, Karina Rønlund, Lise Graversen, Jannie Assenholt, Kjeld Schmiegelow, Karin Wadt, Anne‐Marie Gerdes, Thomas v. O. Hansen
Publikováno v:
Molecular Genetics & Genomic Medicine, Vol 12, Iss 11, Pp n/a-n/a (2024)
ABSTRACT Background Pathogenic variants in the mismatch repair genes are associated with an elevated lifetime risk of colorectal cancer (CRC). We previously identified two variants of uncertain significance (VUS) in the MLH1 gene, c.696_698del, p.(Cy
Externí odkaz:
https://doaj.org/article/3138d238b0bc48cdadc8df08238a908f
Publikováno v:
JCO Global Oncology, Vol , Iss 10 (2024)
Externí odkaz:
https://doaj.org/article/5f852f9e41c34024a30570e198b115b7
Autor:
Marie P. Schützmann, Filip Hasecke, Sarah Bachmann, Mara Zielinski, Sebastian Hänsch, Gunnar F. Schröder, Hans Zempel, Wolfgang Hoyer
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-14 (2021)
Aβ oligomers (AβO) are thought to represent the main toxic species in Alzheimer’s disease but very high Aβ concentrations are required to study them in vitro and it remains unknown what role these off-pathway oligomers play in vivo. Here, the au
Externí odkaz:
https://doaj.org/article/b6f61d39315341c6800e49fcfe3a5b64
Publikováno v:
Frontiers in Neuroscience, Vol 15 (2021)
In the adult human brain, six isoforms of the microtubule-associated protein TAU are expressed, which result from alternative splicing of exons 2, 3, and 10 of the MAPT gene. These isoforms differ in the number of N-terminal inserts (0N, 1N, 2N) and
Externí odkaz:
https://doaj.org/article/c9d1642779794c9d8d32888464acdd0d
Autor:
Ørberg, Sarah Bachmann, Quesada, Carlos M Duarte, Geraldi, Nathan, Sejr, Mikael Kristian, Wegeberg, Susse, Hansen, Jørgen L. S., Krause-Jensen, Dorte
Publikováno v:
Ørberg, S B, Quesada, C M D, Geraldi, N, Sejr, M K, Wegeberg, S, Hansen, J L S & Krause-Jensen, D 2023, ' Prevalent fingerprint of marine macroalgae in arctic surface sediments ', Science of Total Environment . https://doi.org/10.1016/j.scitotenv.2023.165507
Macroalgal forests export much of their production, partly supporting food webs and carbon stocks beyond their habitat, but evidence of their contribution in sediment carbon stocks is poor. We test the hypothesis that macroalgae contribute to carbon
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pure_au_____::b6bd7fb320a2faaed080e9a15be8ee22
https://pure.au.dk/portal/da/publications/prevalent-fingerprint-of-marine-macroalgae-in-arctic-surface-sediments(8cea485d-9da5-4636-ab2e-ad9595a42fae).html
https://pure.au.dk/portal/da/publications/prevalent-fingerprint-of-marine-macroalgae-in-arctic-surface-sediments(8cea485d-9da5-4636-ab2e-ad9595a42fae).html
Publikováno v:
Neuroscience. 461:155-171
Somatodendritic missorting of the axonal protein TAU is a hallmark of Alzheimer’s disease and related tauopathies. Cultured rodent primary neurons and iPSC-derived neurons are used for studying mechanisms of neuronal polarity, including TAU traffic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c22df9a8cde2c30f655c919a1bd98e00
https://doi.org/10.1016/j.neuroscience.2021.01.041
https://doi.org/10.1016/j.neuroscience.2021.01.041
Publikováno v:
Alzheimer's & Dementia. 17
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4fa2cd162d0ff95c3b42af91af02971a
https://doi.org/10.1002/alz.058005
https://doi.org/10.1002/alz.058005
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 2034, p 2034 (2021)
International journal of molecular sciences 22(4), 2034 (2021). doi:10.3390/ijms22042034 special issue: "Special Issue "Modulation of Neuronal Excitability, Synaptic Transmission, and Plasticity in Health and Disease" / Special Issue Editor: Prof. Dr. Claudio Grassi, Guest Editor"
International Journal of Molecular Sciences
International journal of molecular sciences 22(4), 2034 (2021). doi:10.3390/ijms22042034 special issue: "Special Issue "Modulation of Neuronal Excitability, Synaptic Transmission, and Plasticity in Health and Disease" / Special Issue Editor: Prof. Dr. Claudio Grassi, Guest Editor"
International Journal of Molecular Sciences
International journal of molecular sciences 22(4), 2034 (2021). doi:10.3390/ijms22042034 special issue: "Special Issue "Modulation of Neuronal Excitability, Synaptic Transmission, and Plasticity in Health and Disease" / Special Issue Editor: Prof. Dr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d846708607592c77118179f07f52c9b1
https://www.mdpi.com/1422-0067/22/4/2034
https://www.mdpi.com/1422-0067/22/4/2034
Autor:
Sarah Bachmann, Hans Zempel, Marie P. Schützmann, Gunnar F. Schröder, Mara Zielinski, Filip Hasecke, Wolfgang Hoyer, Sebastian Hänsch
Amyloid-{beta} peptide (A{beta}) forms metastable oligomers >50 kD, termed A{beta}Os or protofibrils, that are more effective than A{beta} amyloid fibrils at triggering Alzheimers disease-related processes such as synaptic dysfunction and Tau patholo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fe771e3a1920d2b9856d444cbfde4bea
https://doi.org/10.1101/2020.06.28.175885
https://doi.org/10.1101/2020.06.28.175885
In the adult human brain, six isoforms of the microtubule-associated protein TAU are expressed, which result from alternative splicing of exons 2, 3 and 10 of theMAPTgene. These isoforms differ in the number of N-terminal inserts (0N, 1N, 2N) and C-t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cea88c8f0dacf257218b144e94f9d96e
https://doi.org/10.1101/2020.06.16.154757
https://doi.org/10.1101/2020.06.16.154757