Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Sarah B H Ng"'
Autor:
Aye-Aye Thike, Cindy Lim, Puay Hoon Tan, Sau Yeen Loke, David F. Callen, Yoon Sim Yap, Iain Beehuat Tan, Ann S. G. Lee, Jeffrey Chun Tatt Lim, Swee-Ho Lim, Claire Hian Tzer Chan, Aldo Prawira, Sarah B. H. Ng, Prabhakaran Munusamy, Kong-Wee Ong, Wei-Sean Yong
Publikováno v:
Breast cancer research and treatment. 171(3)
The purpose of the study was to improve the understanding of NF1-associated breast cancer, given the increased risk of breast cancer in this tumour predisposition syndrome and the limited data. We identified 18 women with NF1 and breast cancer at our
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9cd77fb30b30c09f3a70f85f2a46eaa2
https://pubmed.ncbi.nlm.nih.gov/29926297
https://pubmed.ncbi.nlm.nih.gov/29926297
Autor:
Paul Shannon, Holly K. Tabor, Kati J. Buckingham, Deborah A. Nickerson, Ethylin Wang Jabs, Karin M. Dent, Chad D. Huff, Jay Shendure, Sarah B H Ng, Michael J. Bamshad, Choli Lee, Abigail W. Bigham
Publikováno v:
Nature genetics
We demonstrate the first successful application of exome sequencing to discover the gene for a rare mendelian disorder of unknown cause, Miller syndrome (MIM%263750). For four affected individuals in three independent kindreds, we captured and sequen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::daa85958c04c6318a53784937b38069b
http://europepmc.org/articles/PMC2847889
http://europepmc.org/articles/PMC2847889
Autor:
Choli Lee, Steven D. Flygare, Michelle Wong, Peggy D. Robertson, Deborah A. Nickerson, Jay Shendure, Abigail W. Bigham, Evan E. Eichler, Arindam Bhattacharjee, Michael J. Bamshad, Emily H. Turner, Tristan Shaffer, Sarah B H Ng
Publikováno v:
Nature. 461:272-276
Genome-wide association studies suggest that common genetic variants explain only a modest fraction of heritable risk for common diseases, raising the question of whether rare variants account for a significant fraction of unexplained heritability. A
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::90492567c5ddbea9b273a2b8818f93c0
https://doi.org/10.1038/nature08250
https://doi.org/10.1038/nature08250
Publikováno v:
Molecular and Cellular Biology. 26:2688-2696
Most eukaryotic genes are transcribed by RNA polymerase II (Pol II), including those that produce mRNAs and many noncoding functional RNAs. Proper expression of these genes requires efficient termination by Pol II to avoid transcriptional interferenc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::15e4ec5ebe61b5f88f184334c0f3f6c1
https://doi.org/10.1128/mcb.26.7.2688-2696.2006
https://doi.org/10.1128/mcb.26.7.2688-2696.2006