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of 8
pro vyhledávání: '"Sarah B Beynon"'
Autor:
Amanda L Wright, Raphael Zinn, Barbara Hohensinn, Lyndsey M Konen, Sarah B Beynon, Richard P Tan, Ian A Clark, Andrea Abdipranoto, Bryce Vissel
Publikováno v:
PLoS ONE, Vol 8, Iss 4, p e59586 (2013)
Recent human trials of treatments for Alzheimer's disease (AD) have been largely unsuccessful, raising the idea that treatment may need to be started earlier in the disease, well before cognitive symptoms appear. An early marker of AD pathology is th
Externí odkaz:
https://doaj.org/article/aa2d2c1613f94623aac0a56d33b91559
Autor:
Frederick R. Walker, Sarah J. Johnson, Ross J. Tynan, Jason J. Woods, Sarah B. Beynon, Michael Nilsson, Madeleine Hinwood
Publikováno v:
Acta Neuropathologica. 126:75-91
Chronic stress is well recognized to decrease the number of GFAP⁺ astrocytes within the prefrontal cortex (PFC). Recent research, however, has suggested that our understanding of how stress alters astrocytes may be incomplete. Specifically, chronic
Autor:
Frederick R. Walker, Sarah B. Beynon
Publikováno v:
Neuroscience. 225:162-171
Recently it has become apparent that microglia play a role not only in responding to insults within the central nervous system but also in responding to changes in synaptic activity and potentially modulating synaptic function. This has led to an eno
Publikováno v:
Journal of Neuroinflammation
Background Microglial morphology within the healthy brain has been the subject of a number of observational studies. These have suggested that microglia may consist of separate classes, which possess substantially different morphological features. Cr
Autor:
Patrick Kuter, Sarah J. Johnson, Frederick R. Walker, Ratchaniporn Kongsui, Michael Nilsson, Sarah B. Beynon, J. Mayhew
Publikováno v:
Brain, behavior, and immunity. 42
A number of studies have identified that mutations in the P2X7 receptor occur with a significantly higher incidence in individuals with major depression. Consistent with these findings, a number of preclinical studies have identified that mice in whi
Autor:
F. Rohan Walker, Sarah B. Beynon, Zidan Zhao, Murray J. Cairns, Ratchaniporn Kongsui, Michael Nilsson, Kimberley A Jones
Publikováno v:
Brain, behavior, and immunity. 37
Microglia are unique cells within the central nervous system because of their biophysical independence. As a result of this unusual property the cells must undergo significant structural remodelling in order to engage and connect with other elements
Publikováno v:
Brain, Behavior, and Immunity. 32:e20-e21
Astrocytes play a critical role in maintaining neuronal homeostasis. It is for this reason, that there has been considerable interest in understanding how exposure to chronic stress alters the function of these cells. In the current study we wished t
Autor:
Bryce Vissel, Amanda L. Wright, Sarah B. Beynon, Andrea Abdipranoto, Raphael Zinn, Richard P. Tan, Lyndsey M. Konen, Barbara Hohensinn, Ian A. Clark
Publikováno v:
PLoS ONE
PLoS ONE, Vol 8, Iss 4, p e59586 (2013)
PLoS ONE, Vol 8, Iss 4, p e59586 (2013)
Recent human trials of treatments for Alzheimer's disease (AD) have been largely unsuccessful, raising the idea that treatment may need to be started earlier in the disease, well before cognitive symptoms appear. An early marker of AD pathology is th