Zobrazeno 1 - 10
of 58
pro vyhledávání: '"Sarah Asad"'
Autor:
Adith Abraham, Carlos H. Barcenas, Richard J. Bleicher, Adam L. Cohen, Sara H. Javid, Ellis G. Levine, Nancy U. Lin, Beverly Moy, Joyce C. Niland, Antonio C. Wolff, Michael J. Hassett, Sarah Asad, Daniel G. Stover
Publikováno v:
Breast, Vol 67, Iss , Pp 89-93 (2023)
Background: Most metastatic recurrences of triple negative breast cancer (TNBC) occur within five years of diagnosis, yet late relapses of TNBC (lrTNBC) do occur. Our objective was to develop a risk prediction model of lrTNBC using readily available
Externí odkaz:
https://doaj.org/article/5c83b462165b47969c3d65f9cfdccfde
Autor:
Sarah Asad, Adrienne Damicis, Yujing J. Heng, Kathryn Kananen, Katharine A. Collier, Elizabeth J. Adams, Kevin H. Kensler, Gabrielle M. Baker, Robert Wesolowski, Sagar Sardesai, Margaret Gatti-Mays, Bhuvaneswari Ramaswamy, A. Heather Eliassen, Susan E. Hankinson, Fred K. Tabung, Rulla M. Tamimi, Daniel G. Stover
Publikováno v:
Breast Cancer Research, Vol 24, Iss 1, Pp 1-16 (2022)
Abstract Background Breast tumor immune infiltration is clearly associated with improved treatment response and outcomes in breast cancer. However, modifiable patient factors associated with breast cancer immune infiltrates are poorly understood. The
Externí odkaz:
https://doaj.org/article/bfd391b7b4c543cc8e9f6b20a3f6dcf9
Autor:
Otto Metzger-Filho, Katharine Collier, Sarah Asad, Peter J. Ansell, Mark Watson, Junu Bae, Mathew Cherian, Joyce O’Shaughnessy, Michael Untch, Hope S. Rugo, Jens B. Huober, Mehra Golshan, William M. Sikov, Gunter von Minckwitz, Priya Rastogi, Lang Li, Lijun Cheng, David Maag, Norman Wolmark, Carsten Denkert, W. Fraser Symmans, Charles E. Geyer, Sibylle Loibl, Daniel G. Stover
Publikováno v:
npj Breast Cancer, Vol 7, Iss 1, Pp 1-6 (2021)
Abstract In the BrighTNess trial, carboplatin added to neoadjuvant chemotherapy (NAC) was associated with increased pathologic complete response (pCR) rates in patients with stage II/III triple-negative breast cancer (TNBC). In this matched cohort st
Externí odkaz:
https://doaj.org/article/c6af5c9ea1394c7ab85bf5141ac651b6
Autor:
Zachary T. Weber, Katharine A. Collier, David Tallman, Juliet Forman, Sachet Shukla, Sarah Asad, Justin Rhoades, Samuel Freeman, Heather A. Parsons, Nicole O. Williams, Romualdo Barroso-Sousa, Elizabeth H. Stover, Haider Mahdi, Carrie Cibulskis, Niall J. Lennon, Gavin Ha, Viktor A. Adalsteinsson, Sara M. Tolaney, Daniel G. Stover
Publikováno v:
Genome Medicine, Vol 13, Iss 1, Pp 1-17 (2021)
Abstract Background Circulating tumor DNA (ctDNA) offers minimally invasive means to repeatedly interrogate tumor genomes, providing opportunities to monitor clonal dynamics induced by metastasis and therapeutic selective pressures. In metastatic can
Externí odkaz:
https://doaj.org/article/c88b661c2dd14e5595a5247ba01a0bfe
Autor:
Yiqing Zhang, Sarah Asad, Zachary Weber, David Tallman, William Nock, Meghan Wyse, Jerome F. Bey, Kristin L. Dean, Elizabeth J. Adams, Sinclair Stockard, Jasneet Singh, Eric P. Winer, Nancy U. Lin, Yi-Zhou Jiang, Ding Ma, Peng Wang, Leming Shi, Wei Huang, Zhi-Ming Shao, Mathew Cherian, Maryam B. Lustberg, Bhuvaneswari Ramaswamy, Sagar Sardesai, Jeffrey VanDeusen, Nicole Williams, Robert Wesolowski, Samilia Obeng-Gyasi, Gina M. Sizemore, Steven T. Sizemore, Claire Verschraegen, Daniel G. Stover
Publikováno v:
BMC Cancer, Vol 21, Iss 1, Pp 1-13 (2021)
Abstract Background Triple-negative breast cancer (TNBC) is a heterogeneous disease and we have previously shown that rapid relapse of TNBC is associated with distinct sociodemographic features. We hypothesized that rapid versus late relapse in TNBC
Externí odkaz:
https://doaj.org/article/4d0a4dc2363b40cfb12c3b677a3f7f36
Autor:
Gisell Castillo, Manoj Lalu, Sarah Asad, Madison Foster, Natasha Kekre, Dean Fergusson, Terry Hawrysh, Harold Atkins, Kednapa Thavorn, Joshua Montroy, Stuart Schwartz, Robert Holt, Raewyn Broady, Justin Presseau, on behalf of the GO CART team
Publikováno v:
Trials, Vol 22, Iss 1, Pp 1-13 (2021)
Abstract Background Novel therapies often fail to reach the bedside due to low trial recruitment rates. Prior to conducting one of the first chimeric antigen receptor (CAR) T cell therapy trials in Canada, we used the Theoretical Domains Framework, a
Externí odkaz:
https://doaj.org/article/430aa40df7a447f89b64632aa30c865a
Autor:
Madison Foster, Dean A Fergusson, Terry Hawrysh, Justin Presseau, Natasha Kekre, Stuart Schwartz, Gisell Castillo, Sarah Asad, Grace Fox, Harold Atkins, Kednapa Thavorn, Joshua Montroy, Robert A Holt, Zarah Monfaredi, Manoj M Lalu
Publikováno v:
Research Involvement and Engagement, Vol 6, Iss 1, Pp 1-10 (2020)
Abstract Aim Though patient engagement in clinical research is growing, recent reports suggest few clinical trials report on such activities. To address this gap, we describe our approach to patient engagement in the development of a clinical trial p
Externí odkaz:
https://doaj.org/article/41291d56e02947a0aa68b46ceb1c3cfe
Autor:
Elizabeth J. Adams, Sarah Asad, Raquel Reinbolt, Katharine A. Collier, Mahmoud Abdel-Rasoul, Susan Gillespie, James L. Chen, Mathew A. Cherian, Anne M. Noonan, Sagar Sardesai, Jeffrey VanDeusen, Robert Wesolowski, Nicole Williams, Charles L. Shapiro, Erin R. Macrae, Robert Pilarski, Amanda E. Toland, Leigha Senter, Bhuvaneswari Ramaswamy, Clara N. Lee, Maryam B. Lustberg, Daniel G. Stover
Publikováno v:
BMC Cancer, Vol 20, Iss 1, Pp 1-11 (2020)
Abstract Background To assess metastatic breast cancer (MBC) patient psychological factors, perceptions, and comprehension of tumor genomic testing. Methods In a prospective, single institution, single-arm trial, patients with MBC underwent next-gene
Externí odkaz:
https://doaj.org/article/2f48ce7ba64647fa9b6238930db202e1
Autor:
Justin Presseau, Kednapa Thavorn, Joshua Montroy, Natasha Kekre, Gisell Castillo, Sarah Asad, Madison Foster, Terry Hawrysh, Harold Atkins, Stuart Schwartz, Robert A Holt, Raewyn Broady
Publikováno v:
BMJ Open, Vol 11, Iss 3 (2021)
Objectives Bench to bedside translation of groundbreaking treatments like chimeric antigen receptor T (CAR-T) cell therapy depends on patient participation in early phase trials. Unfortunately, many novel therapies fail to be adequately evaluated due
Externí odkaz:
https://doaj.org/article/e15ae9c463df487f90a74d002eadfad4
Autor:
Andrea Janette Chow, Dean Anthony Fergusson, Dugald Seely, Sarah Young, Anne Pitman, Julie Ennis, Sarah Asad, Justin Presseau
Publikováno v:
University of Ottawa Journal of Medicine, Vol 7, Iss 2 (2017)
Objectives: This study aims to identify the personal goals of women with breast cancer, to describe the characteristics of partici- pants’ personal goals over four months, and to identify barriers and facilitators to their pursuit. Methods: This p
Externí odkaz:
https://doaj.org/article/61b3be89345c40be842b1fbb212791f6