Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Sarah Aref"'
Autor:
Ahmad Bakur Mahmoud, Reham Ajina, Sarah Aref, Manar Darwish, May Alsayb, Mustafa Taher, Shaker A. AlSharif, Anwar M. Hashem, Almohanad A. Alkayyal
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Glioblastoma multiforme (GBM) is the most common and aggressive malignant brain tumor of the central nervous system and has a very poor prognosis. The current standard of care for patients with GBM involves surgical resection, radiotherapy, and chemo
Externí odkaz:
https://doaj.org/article/9c4379e7569f421fa987f6e97a923bcd
Publikováno v:
Viruses, Vol 8, Iss 10, p 294 (2016)
Oncolytic virotherapeutic agents are likely to become serious contenders in cancer treatment. The vaccine strain of measles virus is an agent with an impressive range of oncolytic activity in pre-clinical trials with increasing evidence of safety and
Externí odkaz:
https://doaj.org/article/2dcf312c22cb4e7988dd65da7e8fd377
Publikováno v:
Ain Shams Dental Journal. 23:78-85
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::335cee671ace33b682f71293058e0b3b
https://doi.org/10.21608/asdj.2021.96746.1074
https://doi.org/10.21608/asdj.2021.96746.1074
Autor:
Sarah Aref, Daniel Leongamornlert, Richard K. Burt, Adele K. Fielding, Dina Ahmed Said Aly Okasha, Aditi Dey, Katharine Bailey, Anna Castleton, Rachel J. Mitchell
Publikováno v:
Mol Ther
The mechanism of tumor-selective replication of oncolytic measles virus (MV) is poorly understood. Using a stepwise model of cellular transformation, in which oncogenic hits were additively expressed in human bone marrow-derived mesenchymal stromal c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f9ecbbea2f748c09f74c65351060f109
https://doi.org/10.1016/j.ymthe.2020.01.027
https://doi.org/10.1016/j.ymthe.2020.01.027
Autor:
Nawal A. Ahmed, Sarah Aref, Noha Samir, Magda F. Mohamed, Yassmen Ali, Ismail A. Abdelhamid, Omnia Hossam, Aya E. Ali, Amr M. Abdelmoniem, Mervat S. Mohamed
Publikováno v:
Bioorganic Chemistry. 73:43-52
New cyanoacrylamide derivatives were theoretically examined for their binding abilities to a protein model of apoptosis inhibitor proteins x-IAP and c-IAP1 using molecular modeling. The two compounds 5a and 5b proved promising IAP antagonists, where
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fd7ff063696b20b16fd28595a6486d77
https://doi.org/10.1016/j.bioorg.2017.05.012
https://doi.org/10.1016/j.bioorg.2017.05.012
Autor:
Erik Sahai, Krisztina Zuborne-Alapi, Jiten Manji, Amy A Kirkwood, Sarah Aref, Constandina Pospori, Adele K. Fielding, William Day, Ayse U. Akarca, SooWah Lee, Marc R. Mansour, I Puccio, Rachel J. Mitchell, Aditi Dey, Robert C. Muirhead, Katharine Bailey, Teresa Marafioti, Melanie Aguiar, Kristina Kirschner, Steven Hooper, Richard K. Burt, Kenton Cheuk Yan Ng, Cristina Lo Celso
We investigated and modeled the mesenchymal stromal cell (MSC) niche in adult acute lymphoblastic leukemia (ALL). We used gene expression profiling, cytokine/chemokine quantification, flow cytometry, and a variety of imaging techniques to show that M
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::06d45c01fc617a63a81138a5ad83f72d
https://europepmc.org/articles/PMC6856969/
https://europepmc.org/articles/PMC6856969/
Autor:
Al Sheikh, Sarah Aref
Publikováno v:
International Journal of Research in Education and Psychology. 4:168-190
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ebef98edf85059bb1897dd6a58560cd0
https://doi.org/10.12785/ijrep/040106
https://doi.org/10.12785/ijrep/040106
Publikováno v:
Molecular Therapy. 24:S262-S263
The Edmonston-B-derived, vaccine strain of measles virus (MVNSe) has oncolytic activity in numerous preclinical tumor models; safety and some efficacy has been demonstrated in phase 1 clinical trials for myeloma and ovarian carcinoma. Our work focuse
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9a9b05b650e24814f65a5c53f2bf3537
https://doi.org/10.1016/s1525-0016(16)33471-2
https://doi.org/10.1016/s1525-0016(16)33471-2
Autor:
Katharine Bailey, Benjamin Rosen, Aditi Dey, Anna Castleton, Adele K. Fielding, Sarah Aref, Gyorgy Szabadkai
Publikováno v:
Molecular Therapy. 24:S28-S29
Vaccine strain measles virus (MV) is oncolytic in numerous models of malignancy. The mechanism behind the selectivity of MV for transformed cells is poorly understood. To investigate further, an established step-wise model of cellular transformation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::22416d57f78e6c4e7a1b2be5ad849ea3
https://doi.org/10.1016/s1525-0016(16)32874-x
https://doi.org/10.1016/s1525-0016(16)32874-x