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pro vyhledávání: '"Sarah Algino"'
Autor:
Kevin J. Pridham, Zhi Sheng, Deborah F. Kelly, Renee Fajardin, Gary R Simonds, Sujuan Guo, Yanping Liang, Cara M. Rodgers, Lamvy Le, Sarah Algino, Robin T. Varghese
Publikováno v:
Neuro-Oncology. 20:494-505
Background Glioblastoma (GBM) is difficult to treat. Phosphoinositide 3-kinase (PI3K) is an attractive therapeutic target for GBM; however, targeting this pathway to effectively treat GBM is not successful because the roles of PI3K isoforms remain to