Zobrazeno 1 - 10
of 252
pro vyhledávání: '"Sarah A. Spencer"'
Autor:
Hasan U. Banna, Mary Slayo, James A. Armitage, Blanca del Rosal, Loretta Vocale, Sarah J. Spencer
Publikováno v:
Journal of Neuroinflammation, Vol 21, Iss 1, Pp 1-16 (2024)
Abstract Recent years have seen significant advances in diagnostic testing of central nervous system (CNS) function and disease. However, there remain challenges in developing a comprehensive suite of non- or minimally invasive assays of neural healt
Externí odkaz:
https://doaj.org/article/73416239739549a38d73b5f59fc953b7
Autor:
Larissa Marcely Gomes Cassiano, Karina Barbosa de Queiroz, Thais Veronez de Andrade Martins, Ana Luiza Azevedo Maia, Milene Alvarenga Rachid, Sarah J. Spencer, Roney Santos Coimbra
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
BackgroundPneumococcal meningitis (PM) triggers apoptotic neuronal and progenitor cell death in the hippocampal dentate gyrus (DG), resulting in subsequent cognitive impairment. Microglia play a crucial role in PM-induced hippocampal damage. While th
Externí odkaz:
https://doaj.org/article/a78d738aedfd41a6a072d9bdf0112c78
Autor:
Jackson L. K. Yip, Soniya Xavier, Gayathri K. Balasuriya, Elisa L. Hill-Yardin, Sarah J. Spencer
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Intestinal macrophages are well-studied for their conventional roles in the immune response against pathogens and protecting the gut from chronic inflammation. However, these macrophages may also have additional functional roles in gastrointestinal m
Externí odkaz:
https://doaj.org/article/6ccc458d0e7f437eb9fc3059bc0cb42e
Publikováno v:
Frontiers in Neurology, Vol 14 (2023)
Hyper-activity of the brain’s innate immune cells, microglia, is a hallmark of multiple sclerosis (MS). However, it is not clear whether this involvement of microglia is beneficial or detrimental or whether manipulating microglial activity may be t
Externí odkaz:
https://doaj.org/article/23f3f723c8ee4866a8ec325183ebea53
Autor:
Nathalia Garrido-Torres, Lucas Cerrillos, Susana García Cerro, Alberto Pérez Gómez, Manuel Canal-Rivero, Beatriz de Felipe, Luis Alameda, Renata Marqués Rodríguez, Sergio Anillo, Julia Praena, Cristina Duque Sánchez, Cristina Roca, María Paniagua, Alvaro López Díaz, Rafael Romero-García, Peter Olbrich, Martín de Porres Puertas Albarracín, Pablo Reguera Pozuelo, Irene Luján Sosa, María Begoña Moreno Dueñas, Rocío Pineda Cachero, Lidia Zamudio Juan, Verónica García Rumi, Mercedes Guerrero Benitez, Rosario Figueroa, Antonio Manuel Martín Rendón, Antonio Partida, María Isabel Rodríguez Cocho, Carmen Gallardo Trujillo, Isabel Gallego Jiménez, Sarah García Spencer, Marta Gómez Verdugo, Cintia Bermejo Fernández, María Pérez Benito, Rafael Esteban Castillo Reina, Angela Cejudo López, Candela Sánchez Tomás, María Ángeles Chacón Gamero, Ana Rubio, Amanda Moreno Mellado, Víctor Ramos Herrero, Ella Starr, Marta González Fernández de Palacios, Elena García Victori, Antonio Pavón Delgado, Ismael Fernández Cuervo, Alejandro Arias Ruiz, Irene Esperanza Menéndez Gil, Inés Domínguez Gómez, Itziar Coca Mendoza, Rosa Ayesa-Arriola, Lourdes Fañanas, Juan C Leza, José M Cisneros, Javier Sánchez Céspedes, Ezequiel Ruiz-Mateos, Benedicto Crespo-Facorro, Miguel Ruiz-Veguilla
Publikováno v:
Frontiers in Pediatrics, Vol 10 (2022)
The COVID-19 pandemic represents a valuable opportunity to carry out cohort studies that allow us to advance our knowledge on pathophysiological mechanisms of neuropsychiatric diseases. One of these opportunities is the study of the relationships bet
Externí odkaz:
https://doaj.org/article/19f752c4f64a46d08c0fda8b08f193e4
Autor:
Christie C. Browne, Daria Korobanova, Prabin Chemjong, Anthony W. F. Harris, Nick Glozier, John Basson, Sarah-Jane Spencer, Kimberlie Dean
Publikováno v:
Frontiers in Psychiatry, Vol 13 (2022)
PurposeThe prison-to-community transition period is one of high risk and need, particularly for those with mental illness. Some individuals cycle in and out of prison for short periods with little opportunity for mental health stabilization or servic
Externí odkaz:
https://doaj.org/article/7e1f9eeda68c48579eb4720ae1a39654
Autor:
Moritz J. Schmidt, Ashish Gupta, Christien Bednarski, Stefanie Gehrig-Giannini, Florian Richter, Christian Pitzler, Michael Gamalinda, Christina Galonska, Ryo Takeuchi, Kui Wang, Caroline Reiss, Kerstin Dehne, Michael J. Lukason, Akiko Noma, Cindy Park-Windhol, Mariacarmela Allocca, Albena Kantardzhieva, Shailendra Sane, Karolina Kosakowska, Brian Cafferty, Jan Tebbe, Sarah J. Spencer, Scott Munzer, Christopher J. Cheng, Abraham Scaria, Andrew M. Scharenberg, André Cohnen, Wayne M. Coco
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-12 (2021)
Abstract Streptococcus pyogenes (Spy) Cas9 has potential as a component of gene therapeutics for incurable diseases. One of its limitations is its large size, which impedes its formulation and delivery in therapeutic applications. Smaller Cas9s are a
Externí odkaz:
https://doaj.org/article/164ce27f7fcc420f8085cc9624163a4b
Autor:
Moritz J. Schmidt, Ashish Gupta, Christien Bednarski, Stefanie Gehrig-Giannini, Florian Richter, Christian Pitzler, Michael Gamalinda, Christina Galonska, Ryo Takeuchi, Kui Wang, Caroline Reiss, Kerstin Dehne, Michael J. Lukason, Akiko Noma, Cindy Park-Windhol, Mariacarmela Allocca, Albena Kantardzhieva, Shailendra Sane, Karolina Kosakowska, Brian Cafferty, Jan Tebbe, Sarah J. Spencer, Scott Munzer, Christopher J. Cheng, Abraham Scaria, Andrew M. Scharenberg, André Cohnen, Wayne M. Coco
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-1 (2023)
Externí odkaz:
https://doaj.org/article/ea3084e9d59245a1998e55dd20e1cb3d
Autor:
Aleksandar Dobric, Simone N. De Luca, Huei Jiunn Seow, Hao Wang, Kurt Brassington, Stanley M. H. Chan, Kevin Mou, Jonathan Erlich, Stella Liong, Stavros Selemidis, Sarah J. Spencer, Steven Bozinovski, Ross Vlahos
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 15 (2022)
Background and ObjectiveNeurocognitive dysfunction is present in up to ∼61% of people with chronic obstructive pulmonary disease (COPD), with symptoms including learning and memory deficiencies, negatively impacting the quality of life of these ind
Externí odkaz:
https://doaj.org/article/a877ab5c1eb34adcb041374018a5eb00
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology, Vol 12, Iss 5, Pp 1701-1718 (2021)
Intestinal macrophages play a key role in the gut immune system and the regulation of gastrointestinal physiology, including gut motility and secretion. Their ability to keep the gut from chronic inflammation despite constantly facing foreign antigen
Externí odkaz:
https://doaj.org/article/8de6406d81c948259231c7ad8529f75c