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pro vyhledávání: '"Sarah A. Simko"'
Autor:
David B. Shackelford, Steven M. Dubinett, Tonya C. Walser, Michael C. Fishbein, David B. Stout, Clara Magyar, Sarah A. Simko, Atsuko Seki, Evan Abt, Robert McMickle, Milica Momcilovic
Inactivation of the LKB1 tumor suppressor is a frequent event in non–small cell lung carcinoma (NSCLC) leading to the activation of mTOR complex 1 (mTORC1) and sensitivity to the metabolic stress inducer phenformin. In this study, we explored the c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5c41283f603f283b081b1606bb095d33
https://doi.org/10.1158/0008-5472.c.6508224.v1
https://doi.org/10.1158/0008-5472.c.6508224.v1
Autor:
David B. Shackelford, Steven M. Dubinett, Tonya C. Walser, Michael C. Fishbein, David B. Stout, Clara Magyar, Sarah A. Simko, Atsuko Seki, Evan Abt, Robert McMickle, Milica Momcilovic
Treatment of LKB1 mutant and LKB1 wildtype NSCLC lines with phenformin, MLN0128 or combination leads to loss of cellular ATP (S1); Metabolite analysis of NSCLC human cell line expressing dox inducible 4E-BP1 4Ala protein and control vector (S2); Biom
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0a88ba89be210c93462dc40c00c66b22
https://doi.org/10.1158/0008-5472.22411434.v1
https://doi.org/10.1158/0008-5472.22411434.v1
Autor:
Michael C. Fishbein, David B. Stout, Robert McMickle, Evan R. Abt, Atsuko Seki, Milica Momcilovic, Steven M. Dubinett, Sarah A. Simko, David B. Shackelford, Tonya C. Walser, Clara E. Magyar
Publikováno v:
Cancer research. 75(22)
Inactivation of the LKB1 tumor suppressor is a frequent event in non–small cell lung carcinoma (NSCLC) leading to the activation of mTOR complex 1 (mTORC1) and sensitivity to the metabolic stress inducer phenformin. In this study, we explored the c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c0bd41ba16f5980994eeb5b730702077
https://pubmed.ncbi.nlm.nih.gov/26574479
https://pubmed.ncbi.nlm.nih.gov/26574479
