Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Sarah A. Molton"'
Autor:
Massimo Libra, Ferdinando Nicoletti, Ellis W.T. Wong, Sarah A Molton, Martin McMahon, James A. McCubrey, Giovanni Ligresti, Alberto M. Martelli, Negin Misaghian, Camilla Evangelisti, Jakob Troppmair, Jörg Bäsecke, Stephen L. Abrams, Linda S. Steelman
Publikováno v:
Leukemia. 22:2080-2090
A cytokine-dependent (FL5.12), drug-sensitive, p53 wild type (WT) and a doxorubicin-resistant derivative line (FL/Doxo) were used to determine the mechanisms that could result in drug resistance of early hematopoietic precursor cells. Drug resistance
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8043ab1743bb3f7a2f56f0056e770c6e
https://doi.org/10.1038/leu.2008.207
https://doi.org/10.1038/leu.2008.207
Autor:
Sebastien Cagnol, G. R. Thomas, Kimberly A. Jong, Robert A. Cartlidge, Martin McMahon, Sarah A Molton, Andrew J. Finch
Publikováno v:
Pigment Cell & Melanoma Research. 21:534-544
Somatic activating mutations of BRAF are the earliest and most common genetic abnormality detected in the genesis of human melanoma. However, the mechanism(s) by which activated BRAF promotes melanoma cell cycle progression and/or survival remain unc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::259b88166b363ac74a52bf5ab4d0bc05
https://doi.org/10.1111/j.1755-148x.2008.00491.x
https://doi.org/10.1111/j.1755-148x.2008.00491.x
Autor:
Daniel E Todd, Kathryn Balmanno, Catherine Newson, Sarah A. Molton, Claire R. Weston, Simon J. Cook, Andrew Garner
Publikováno v:
Cellular Signalling. 17:1412-1422
The conditional protein kinase DeltaMEKK3:ER* allows activation of the mitogen-activated and stress-activated protein kinases (MAPKs and SAPKs) without imposing a primary cellular stress or damage. Such separation of stress from stress-induced signal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e7e905f852b4bb02bcd041866d98c6e5
https://doi.org/10.1016/j.cellsig.2005.02.006
https://doi.org/10.1016/j.cellsig.2005.02.006
Publikováno v:
Pharmaceutical Research. 17:1265-1272
Purpose. Recent advances in combinatorial chemistry and high throughput screens for pharmacologic activity have created an increasing demand for in vitrohigh throughput screens for toxicological evaluation in the early phases of drug discovery.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::41b71db445fa6db9a34e798060627d4a
https://doi.org/10.1023/a:1026495503939
https://doi.org/10.1023/a:1026495503939
Autor:
Robert A, Cartlidge, G R, Thomas, Sebastien, Cagnol, Kimberly A, Jong, Sarah A, Molton, Andrew J, Finch, Martin, McMahon
Publikováno v:
Pigment cellmelanoma research. 21(5)
Somatic activating mutations of BRAF are the earliest and most common genetic abnormality detected in the genesis of human melanoma. However, the mechanism(s) by which activated BRAF promotes melanoma cell cycle progression and/or survival remain unc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::32bc0ae0048f8d42f670e49eb900e8fd
https://pubmed.ncbi.nlm.nih.gov/18715233
https://pubmed.ncbi.nlm.nih.gov/18715233
Autor:
Andrew P. Garner, Claire R. Weston, Catherine Newson, Kathryn Balmanno, Ruth M Densham, Sarah A Molton, Linda Scott, Daniel E Todd, Simon J. Cook
Publikováno v:
Oncogene. 23(19)
To study the mechanisms by which mitogen- and stress-activated protein kinases regulate cell cycle re-entry, we have used a panel of conditional kinases that stimulate defined MAPK or SAPK cascades. Activation of DeltaMEKK3:ER* during serum restimula
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8c7065889b43e55e35794467ab4f20e8
https://pubmed.ncbi.nlm.nih.gov/14981547
https://pubmed.ncbi.nlm.nih.gov/14981547