Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Sarah A. Molton"'
Autor:
Massimo Libra, Ferdinando Nicoletti, Ellis W.T. Wong, Sarah A Molton, Martin McMahon, James A. McCubrey, Giovanni Ligresti, Alberto M. Martelli, Negin Misaghian, Camilla Evangelisti, Jakob Troppmair, Jörg Bäsecke, Stephen L. Abrams, Linda S. Steelman
Publikováno v:
Leukemia. 22:2080-2090
A cytokine-dependent (FL5.12), drug-sensitive, p53 wild type (WT) and a doxorubicin-resistant derivative line (FL/Doxo) were used to determine the mechanisms that could result in drug resistance of early hematopoietic precursor cells. Drug resistance
Autor:
Sebastien Cagnol, G. R. Thomas, Kimberly A. Jong, Robert A. Cartlidge, Martin McMahon, Sarah A Molton, Andrew J. Finch
Publikováno v:
Pigment Cell & Melanoma Research. 21:534-544
Somatic activating mutations of BRAF are the earliest and most common genetic abnormality detected in the genesis of human melanoma. However, the mechanism(s) by which activated BRAF promotes melanoma cell cycle progression and/or survival remain unc
Autor:
Daniel E Todd, Kathryn Balmanno, Catherine Newson, Sarah A. Molton, Claire R. Weston, Simon J. Cook, Andrew Garner
Publikováno v:
Cellular Signalling. 17:1412-1422
The conditional protein kinase DeltaMEKK3:ER* allows activation of the mitogen-activated and stress-activated protein kinases (MAPKs and SAPKs) without imposing a primary cellular stress or damage. Such separation of stress from stress-induced signal
Publikováno v:
Pharmaceutical Research. 17:1265-1272
Purpose. Recent advances in combinatorial chemistry and high throughput screens for pharmacologic activity have created an increasing demand for in vitrohigh throughput screens for toxicological evaluation in the early phases of drug discovery.
Autor:
Robert A, Cartlidge, G R, Thomas, Sebastien, Cagnol, Kimberly A, Jong, Sarah A, Molton, Andrew J, Finch, Martin, McMahon
Publikováno v:
Pigment cellmelanoma research. 21(5)
Somatic activating mutations of BRAF are the earliest and most common genetic abnormality detected in the genesis of human melanoma. However, the mechanism(s) by which activated BRAF promotes melanoma cell cycle progression and/or survival remain unc
Autor:
Andrew P. Garner, Claire R. Weston, Catherine Newson, Kathryn Balmanno, Ruth M Densham, Sarah A Molton, Linda Scott, Daniel E Todd, Simon J. Cook
Publikováno v:
Oncogene. 23(19)
To study the mechanisms by which mitogen- and stress-activated protein kinases regulate cell cycle re-entry, we have used a panel of conditional kinases that stimulate defined MAPK or SAPK cascades. Activation of DeltaMEKK3:ER* during serum restimula
Autor:
Cartlidge, Robert A.1, Thomas, G. R.1, Cagnol, Sebastien1, Jong, Kimberly A.1, Molton, Sarah A.1, Finch, Andrew J.1, McMahon, Martin1 mcmahon@cc.ucsf.edu
Publikováno v:
Pigment Cell & Melanoma Research. Oct2008, Vol. 21 Issue 5, p534-544. 11p. 3 Black and White Photographs, 3 Graphs.
Autor:
Lucy Hall Greenlaw
This important, though short-lived, periodical (1898-1901) featured exhaustive transcriptions of the early records of Massachusetts, and particularly of the following Massachusetts counties and towns: Plymouth County, Bristol County, Kingston, Yarmou
Autor:
Robert W. Barnes
Baltimore County originally embraced all or parts of present-day Anne Arundel, Carroll, Harford, and Cecil counties, and here for the first time is a book that provides comprehensive genealogical data on the hundreds of families and thousands of indi
Autor:
Gary Boyd Roberts
This work contains all of the articles on Rhode Island families that had been published in'The New England Historical and Genealogical Register'since 1846. Except for articles relating to the immigrant origins of Rhode Island families, which have app