Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Sarah A. Eggleton"'
Autor:
Pamela J. Russell, Ross Darius Farhadieh, Arash Salardini, Sarah A. Eggleton, Robert Smee, Charles Geoffrey Gordon Rees, Jia-Lin Yang
Publikováno v:
ANZ Journal of Surgery. 79:48-54
Background: Field cancerization is a feature of head and neck squamous cell carcinoma. No biological marker in the index tumour has been correlated to the development of second primary tumours (SPT). Cyclin A1 is a cell cycle regulator and a downstre
Autor:
James G. Kench, Robert L. Sutherland, David I. Quinn, Susan M. Henshall, Phillip D. Stricker, Andrew V. Biankin, Lisa G. Horvath, Sarah A. Eggleton, John J. Grygiel
Publikováno v:
JNCI: Journal of the National Cancer Institute. 98:1420-1424
The risk of metastatic progression for prostate cancer patients who undergo radical prostatectomy is best estimated presently based on prostate-specific antigen (PSA) doubling time (PSADT). However, additional markers of risk are needed to identify p
Autor:
John L. Hopper, Melissa C. Southey, Vanessa M. Hayes, Sarah A. Eggleton, Graham G. Giles, Robert L. Sutherland, Emma J.D. Padilla, Gianluca Severi
Publikováno v:
Cancer Epidemiology, Biomarkers & Prevention. 14:997-999
Vitamin D receptor (VDR), a member of the steroid/thyroid hormone nuclear receptor family, is bound by the steroid hormone 1,25-dihydroxyvitamin D3, which is thought to play a role in the etiology and progression of prostate cancer. Polymorphisms in
Autor:
George Papadatos, Catriona M. McNeil, Robert L. Sutherland, C Fox, Sandra A O'Toole, Julia Beretov, Geoffrey P Delaney, Elias H. Nasser, Adrienne Morey, Con Theocharous, Peter Graham, John H. Kearsley, Ewan K.A. Millar, Lois Browne, Sarah A. Eggleton, Anne Capp
Publikováno v:
Journal of clinical oncology : official journal of the American Society of Clinical Oncology. 27(28)
Purpose To determine the clinical utility of intrinsic molecular phenotype after breast-conserving therapy (BCT) with lumpectomy and whole-breast irradiation with or without a cavity boost. Patients and Methods Four hundred ninety-eight patients with
Autor:
James G. Kench, Emma J.D. Padilla, K. Rasiah, Susan Henshall, Margaret Gardiner-Garden, Jerzy Adamski, M. Chehani Alles, Phillip D. Stricker, Sarah A. Eggleton, Vanessa M. Hayes, Gabriele Möller, Robert L. Sutherland
Publikováno v:
Molecular and cellular endocrinology. 301(1-2)
Steroid hormones and their metabolising enzymes have been studied extensively for their potential role in prostate cancer, with more recent interest in the androgen/estrogen inactivating enzyme 17beta-hydroxysteroid dehydrogenase type 4 (HSD17B4). Ge
Autor:
James G. Kench, Paul Crea, M. Chehani Alles, Claire K. Inman, Christopher J. Ormandy, Niamh C Murphy, Sarah A. Eggleton, Susan Henshall, Robert L. Sutherland, C. Marcelo Sergio, Margaret Gardiner-Garden, Alison J. Butt, Catriona M. McNeil, Luke R. Anderson, Ewan K.A. Millar, Elizabeth A. Musgrove
Publikováno v:
The Journal of steroid biochemistry and molecular biology. 102(1-5)
The oncoprotein c-Myc is frequently overexpressed in breast cancer and ectopic expression in breast cancer cell lines attenuates responses to antiestrogen treatment. Here, we review preliminary data aimed at further elucidating a potential role for c
Autor:
Melissa C. Southey, John L. Hopper, Gianluca Severi, Vanessa M. Hayes, Robert L. Sutherland, Sarah A. Eggleton, Emma J.D. Padilla, Graham G. Giles
Publikováno v:
Cancer epidemiology, biomarkersprevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology. 14(4)
The androgen receptor (AR) gene encodes a transcription factor, which mediates androgen action in target tissues, including the prostate. Prostate cancer is androgen dependent, implicating AR in susceptibility to this male condition. Male pattern bal
Autor:
James G. Kench, Robert L. Sutherland, Simon Junankar, Wade Barret, Susan M. Henshall, Samuel N. Breit, David Brown, Tamara Kuffner, Tao Liu, Dave Smith, Pamela J. Russell, Heiko Johnen, John J. Grygiel, Sarah A. Eggleton, Phillip D. Stricker, K. Rasiah, Asne R. Bauskin, Greg J. Pankhurst, Mark Hunter
Publikováno v:
Cancer research. 65(6)
The extracellular matrix (ECM) is a reservoir of cellular binding proteins and growth factors that are critical for normal cell behavior, and aberrations in the ECM invariably accompany malignancies such as prostate cancer. Carcinomas commonly overex