Zobrazeno 1 - 10
of 240
pro vyhledávání: '"Sarah A. Christensen"'
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-10 (2024)
Abstract Rodent migraine models have been developed to study the underlying molecular mechanisms of migraine, but these need further development and validation to stay relevant. The glyceryl trinitrate (GTN) mouse model with tactile hypersensitivity
Externí odkaz:
https://doaj.org/article/52f64bf8c9504531994e2d11e4b59ba2
Autor:
Song Guo, Rikke Holm Rasmussen, Anders Hay-Schmidt, Messoud Ashina, Ayodeji A. Asuni, Jeppe Møller Jensen, Anja Holm, Sabrina Prehn Lauritzen, Glenn Dorsam, Jens Hannibal, Birgitte Georg, David Møbjerg Kristensen, Jes Olesen, Sarah Louise Christensen
Publikováno v:
The Journal of Headache and Pain, Vol 25, Iss 1, Pp 1-12 (2024)
Abstract Background Pituitary adenylate cyclase-activating peptide (PACAP) is a neuropeptide pivotal in migraine pathophysiology and is considered a promising new migraine drug target. Although intravenous PACAP triggers migraine attacks and a recent
Externí odkaz:
https://doaj.org/article/1b5638b4204d4c57a3832603fc0281f0
Autor:
Hans Carl Hasselbalch, Vibe Skov, Lasse Kjaer, Trine Alma Knudsen, Christina Schjellerup Eickhardt-Dalbøge, Christina Ellervik, Sabrina Cordua, Anders Lindholm Sørensen, Sarah Friis Christensen, Marie Hvelplund Kristiansen, Jes Sanddal Lindholt, Mads Thomassen, Torben A. Kruse, Niels Eske Bruun, Matias Greve Lindholm, Claus Henrik Nielsen, Miklos Egyed, Winfried März, Morten Kranker Larsen, Troels Wienecke
Publikováno v:
Frontiers in Hematology, Vol 3 (2024)
Clonal Hematopoiesis of Indeterminate Potential (CHIP) is associated with an increased risk of cardiovascular diseases (CVD) and is a precursor stage to the BCR-ABL negative chronic myeloproliferative neoplasms (MPNs). These diseases are acquired ste
Externí odkaz:
https://doaj.org/article/b05ed2c1e5ac413eba6f1e617b161752
Autor:
Christina Schjellerup Eickhardt-Dalbøge, Anna Cäcilia Ingham, Henrik V. Nielsen, Kurt Fuursted, Christen Rune Stensvold, Lee O'Brien Andersen, Morten Kranker Larsen, Lasse Kjær, Sarah Friis Christensen, Trine Alma Knudsen, Vibe Skov, Christina Ellervik, Lars Rønn Olsen, Hans Carl Hasselbalch, Jens Jørgen Elmer Christensen, Xiaohui Chen Nielsen
Publikováno v:
Microbiology Spectrum, Vol 11, Iss 5 (2023)
ABSTRACT Essential thrombocythemia (ET) is part of the Philadelphia chromosome-negative myeloproliferative neoplasms. It is characterized by an increased risk of thromboembolic events and also to a certain degree hypermetabolic symptoms. The gut micr
Externí odkaz:
https://doaj.org/article/b3609417a5e84dac83bf1109859a4035
Autor:
Sofie Rosenlund Lau, Frans Waldorff, Anne Holm, Anne Frølich, John Sahl Andersen, Mette Sallerup, Sarah Emilie Christensen, Stine Søndersted Clausen, Tina Drud Due, Pernille Hølmkjær
Publikováno v:
BMC Public Health, Vol 23, Iss 1, Pp 1-12 (2023)
Abstract Introduction Polypharmacy is a common concern, especially in the older population. In some countries more that 50% of all individuals over 60 receive five or more drugs, most often due to multimorbidity and increased longevity. However, poly
Externí odkaz:
https://doaj.org/article/d1dedaf9e6c94980aefaa8201d670429
Autor:
Simone S. E. Nielsen, Mikkel R. Holst, Kristine Langthaler, Sarah Christine Christensen, Elisabeth Helena Bruun, Birger Brodin, Morten S. Nielsen
Publikováno v:
Fluids and Barriers of the CNS, Vol 20, Iss 1, Pp 1-15 (2023)
Abstract The detailed mechanisms by which the transferrin receptor (TfR) and associated ligands traffic across brain capillary endothelial cells (BECs) of the CNS-protective blood–brain barrier constitute an important knowledge gap within maintenan
Externí odkaz:
https://doaj.org/article/19b7d12e1ec14ff993d47e4deb7c4783
Autor:
Song Guo, Charlotte Ernstsen, Anders Hay-Schmidt, David Møbjerg Kristensen, Messoud Ashina, Jes Olesen, Sarah Louise Christensen
Publikováno v:
The Journal of Headache and Pain, Vol 23, Iss 1, Pp 1-11 (2022)
Abstract Background Calcitonin gene-related peptide (CGRP) antagonizing drugs represents the most important advance in migraine therapy for decades. However, these new drugs are only effective in 50–60% of patients. Recent studies have shown that t
Externí odkaz:
https://doaj.org/article/aa93e6ce88a644588aca28d7f4c2313a
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 16 (2023)
Migraine is one of the leading causes of disability worldwide, affecting work and social life. It has been estimated that sales of migraine medicines will reach 12.9 billion USD in 2027. To reduce social impact, migraine treatments must improve, and
Externí odkaz:
https://doaj.org/article/f4d3e5d8b20049f294752367c90fec48
Autor:
Istvan N. Huszar, Menuka Pallebage-Gamarallage, Sarah Bangerter-Christensen, Hannah Brooks, Sean Fitzgibbon, Sean Foxley, Marlies Hiemstra, Amy F.D. Howard, Saad Jbabdi, Daniel Z.L. Kor, Anna Leonte, Jeroen Mollink, Adele Smart, Benjamin C. Tendler, Martin R. Turner, Olaf Ansorge, Karla L. Miller, Mark Jenkinson
Publikováno v:
NeuroImage, Vol 265, Iss , Pp 119792- (2023)
Background: Accurate registration between microscopy and MRI data is necessary for validating imaging biomarkers against neuropathology, and to disentangle complex signal dependencies in microstructural MRI. Existing registration methods often rely o
Externí odkaz:
https://doaj.org/article/267f63747d204042b30e3e21b044b8fb
Publikováno v:
Neurobiology of Disease, Vol 176, Iss , Pp 105946- (2023)
Migraine is a widespread and debilitating neurological condition affecting more than a billion people worldwide. Thus, more effective migraine therapies are highly needed. In the last decade, two endogenous neuropeptides, calcitonin gene-related pept
Externí odkaz:
https://doaj.org/article/eabac6584f354356b1ff1d5a902d3fff