GWAS on retinal vasculometry phenotypes.

Autor: Xiaofan Jiang, Pirro G Hysi, Anthony P Khawaja, Omar A Mahroo, Zihe Xu, Christopher J Hammond, Paul J Foster, Roshan A Welikala, Sarah A Barman, Peter H Whincup, Alicja R Rudnicka, Christopher G Owen, David P Strachan, UK Biobank Eye and Vision Consortium

Publikováno v: PLoS Genetics, Vol 19, Iss 2, p e1010583 (2023)

The eye is the window through which light is transmitted and visual sensory signalling originates. It is also a window through which elements of the cardiovascular and nervous systems can be directly inspected, using ophthalmoscopy or retinal imaging

Externí odkaz: https://doaj.org/article/150ba4a65ad84908a2b6b5575876bebf

Automated Detection and Classification of Oral Lesions Using Deep Learning for Early Detection of Oral Cancer

Autor: Roshan Alex Welikala, Paolo Remagnino, Jian Han Lim, Chee Seng Chan, Senthilmani Rajendran, Thomas George Kallarakkal, Rosnah Binti Zain, Ruwan Duminda Jayasinghe, Jyotsna Rimal, Alexander Ross Kerr, Rahmi Amtha, Karthikeya Patil, Wanninayake Mudiyanselage Tilakaratne, John Gibson, Sok Ching Cheong, Sarah Ann Barman

Publikováno v: IEEE Access, Vol 8, Pp 132677-132693 (2020)

Oral cancer is a major global health issue accounting for 177,384 deaths in 2018 and it is most prevalent in low- and middle-income countries. Enabling automation in the identification of potentially malignant and malignant lesions in the oral cavity

Externí odkaz: https://doaj.org/article/eee5c69116084eb09814003503c3d943

The association between serum lipids and intraocular pressure in 2 large United Kingdom cohorts

Autor: Kian M. Madjedi, Kelsey V. Stuart, Sharon Y.L. Chua, Robert N. Luben, Alasdair Warwick, Louis R. Pasquale, Jae H. Kang, Janey L. Wiggs, Marleen A.H. Lentjes, Hugues Aschard, Naveed Sattar, Paul J. Foster, Anthony P. Khawaja, Mark Chia, Ron Do, Alan Kastner, Jihye Kim, Giovanni Montesano, Denize Atan, Tariq Aslam, Sarah A. Barman, Jenny H. Barrett, Paul Bishop, Peter Blows, Catey Bunce, Roxana O. Carare, Usha Chakravarthy, Michelle Chan, David P. Crabb, Philippa M. Cumberland, Alexander Day, Parul Desai, Bal Dhillon, Andrew D. Dick, Cathy Egan, Sarah Ennis, Paul Foster, Marcus Fruttiger, John E.J. Gallacher, David F. Garway-Heath, Jane Gibson, Dan Gore, Jeremy A. Guggenheim, Chris J. Hammond, Alison Hardcastle, Simon P. Harding, Ruth E. Hogg, Pirro Hysi, Pearse A. Keane, Sir Peng T. Khaw, Gerassimos Lascaratos, Andrew J. Lotery, Tom Macgillivray, Sarah Mackie, Keith Martin, Michelle McGaughey, Bernadette McGuinness, Gareth J. McKay, Martin McKibbin, Danny Mitry, Tony Moore, James E. Morgan, Zaynah A. Muthy, Eoin O’Sullivan, Chris G. Owen, Praveen Patel, Euan Paterson, Tunde Peto, Axel Petzold, Jugnoo S. Rahi, Alicja R. Rudnikca, Jay Self, Sobha Sivaprasad, David Steel, Irene Stratton, Nicholas Strouthidis, Cathie Sudlow, Dhanes Thomas, Emanuele Trucco, Adnan Tufail, Veronique Vitart, Stephen A. Vernon, Ananth C. Viswanathan, Cathy Williams, Katie Williams, Jayne V. Woodside, MaxM. Yates, Jennifer Yip, Yalin Zheng

Publikováno v: Modifiable Risk Factors for Glaucoma Collaboration and the UK Biobank Eye and Vision Consortium, Madjedi, K M, Stuart, K V, Chua, S Y L, Luben, R N, Warwick, A, Pasquale, L R, Kang, J H, Wiggs, J L, Lentjes, M A H, Aschard, H, Sattar, N, Foster, P J, Khawaja, A P, Chia, M, Do, R, Kastner, A, Kim, J, Montesano, G, Atan, D, Aslam, T, Barman, S A, Barrett, J H, Bishop, P, Blows, P, Bunce, C, Carare, R O, Chakravarthy, U, Chan, M, Crabb, D P, Cumberland, P M, Day, A, Desai, P, Dhillon, B, Dick, A D, Egan, C, Ennis, S, Foster, P, Fruttiger, M, Gallacher, J E J, Garway-Heath, D F, Gibson, J, Gore, D, Hogg, R E, McGaughey, M, McGuinness, B, McKay, G J, Paterson, E, Peto, T, Steel, D & Woodside, J V 2022, ' The Association between Serum Lipids and Intraocular Pressure in 2 Large United Kingdom Cohorts ', Ophthalmology, vol. 129, no. 9, pp. 986-996 . https://doi.org/10.1016/j.ophtha.2022.04.023
Modifiable Risk Factors for Glaucoma Collaboration and the UK Biobank Eye and Vision Consortium 2022, ' The Association between Serum Lipids and Intraocular Pressure in 2 Large United Kingdom Cohorts ', Ophthalmology, vol. 129, no. 9, pp. 986-996 . https://doi.org/10.1016/j.ophtha.2022.04.023
Ophthalmology: Journal of The American Academy of Ophthalmology
Ophthalmology: Journal of The American Academy of Ophthalmology, 2022, 129 (9), pp.986-996. ⟨10.1016/j.ophtha.2022.04.023⟩
Ophthalmology, 129(9), 986-996. Elsevier Inc.

Purpose: Serum lipids are modifiable, routinely collected blood test features associated with cardiovascular health. We examined the association of commonly collected serum lipid measures (total cholesterol [TC], high-density lipoprotein cholesterol

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6ee73fd6f3ad69cfc1b0fa0ee7b1daba
https://eprints.soton.ac.uk/470583/

Image collection and annotation platforms to establish a multi‐source database of oral lesions

Autor: Senthilmani Rajendran, Jian Han Lim, Kohgulakuhan Yogalingam, Thomas George Kallarakkal, Rosnah Binti Zain, Ruwan Duminda Jayasinghe, Jyotsna Rimal, Alexander Ross Kerr, Rahmi Amtha, Karthikeya Patil, Roshan Alex Welikala, Ying Zhi Lim, Paolo Remagnino, John Gibson, Wanninayake Mudiyanselage Tilakaratne, Chee Sun Liew, Yi‐Hsin Yang, Sarah Ann Barman, Chee Seng Chan, Sok Ching Cheong

Publikováno v: Oral Diseases.

To describe the development of a platform for image collection and annotation that resulted in a multi-sourced international image dataset of oral lesions to facilitate the development of automated lesion classification algorithms.We developed a web-

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::153cf73dd94cc813e5a735aeeeea31df
https://doi.org/10.1111/odi.14206

Comparison of Associations with Different Macular Inner Retinal Thickness Parameters in a Large Cohort

Autor: Anthony P. Khawaja, Sharon Chua, Pirro G. Hysi, Stelios Georgoulas, Hannah Currant, Tomas W. Fitzgerald, Ewan Birney, Fang Ko, Qi Yang, Charles Reisman, David F. Garway-Heath, Chris J. Hammond, Peng T. Khaw, Paul J. Foster, Praveen J. Patel, Nicholas Strouthidis, Denize Atan, Tariq Aslam, Sarah A. Barman, Jenny H. Barrett, Paul Bishop, Peter Blows, Catey Bunce, Roxana O. Carare, Usha Chakravarthy, Michelle Chan, Sharon Y.L. Chua, David P. Crabb, Philippa M. Cumberland, Alexander Day, Parul Desai, Bal Dhillon, Andrew D. Dick, Cathy Egan, Sarah Ennis, Paul Foster, Marcus Fruttiger, John E.J. Gallacher, Jane Gibson, Dan Gore, Jeremy A. Guggenheim, Alison Hardcastle, Simon P. Harding, Ruth E. Hogg, Pirro Hysi, Pearse A. Keane, Sir Peng T. Khaw, Gerassimos Lascaratos, Andrew J. Lotery, Tom Macgillivray, Sarah Mackie, Keith Martin, Michelle McGaughey, Bernadette McGuinness, Gareth J. McKay, Martin McKibbin, Danny Mitry, Tony Moore, James E. Morgan, Zaynah A. Muthy, Eoin O’Sullivan, Chris G. Owen, Praveen Patel, Euan Paterson, Tunde Peto, Axel Petzold, Jugnoo S. Rahi, Alicja R. Rudnikca, Jay Self, Sobha Sivaprasad, David Steel, Irene Stratton, Cathie Sudlow, Dhanes Thomas, Emanuele Trucco, Adnan Tufail, Veronique Vitart, Stephen A. Vernon, Ananth C. Viswanathan, Cathy Williams, Katie Williams, Jayne V. Woodside, Max M. Yates, Jennifer Yip, Yalin Zheng

Publikováno v: Ophthalmology. 127:62-71

Purpose To describe and compare associations with macular retinal nerve fiber layer (mRNFL), ganglion cell complex (GCC), and ganglion cell–inner plexiform layer (GCIPL) thicknesses in a large cohort. Design Cross-sectional study. Participants We i

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::9c074964d3f87730e7f5d74ccc94ac7a
https://doi.org/10.1016/j.ophtha.2019.08.015