Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Sarah A Wicher"'
Autor:
Sarah A Wicher, Benjamin B Roos, Jacob J Teske, Yun Hua Fang, Christina Pabelick, Y S Prakash
Publikováno v:
PLoS ONE, Vol 16, Iss 7, p e0254710 (2021)
Lung function declines as people age and their lungs become stiffer. With an increasing elderly population, understanding mechanisms that contribute to these structural and functional changes in the aging lung is important. Part of the aging process
Externí odkaz:
https://doaj.org/article/9ed70d7ed6a54bfd8c84a97a7475e3f6
Autor:
Nathan K. LeBrasseur, L. Manlove, Pavan Parikh, Jovanka Ravix, Gary C. Sieck, A.M. Roesler, Sarah A. Wicher, Michael A. Thompson, R.D. Britt, Christina M. Pabelick, Daniel J. Tschumperlin, Y. S. Prakash, Jacob J. Teske, James L. Kirkland
Publikováno v:
American Journal of Respiratory Cell and Molecular Biology
Supplemental O2 (hyperoxia; 30-90% O2) is a necessary intervention for premature infants, but it contributes to development of neonatal and pediatric asthma, necessitating better understanding of contributory mechanisms in hyperoxia-induced changes t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5bb770be63acc63652268501bbc078a0
https://doi.org/10.1165/rcmb.2018-0176oc
https://doi.org/10.1165/rcmb.2018-0176oc
Publikováno v:
American Journal of Physiology-Lung Cellular and Molecular Physiology. 312:L969-L982
Ozone causes vagally mediated airway hyperreactivity and recruits inflammatory cells, including eosinophils, to lungs, where they mediate ozone-induced hyperreactivity 1 day after exposure but are paradoxically protective 3 days later. We aimed to te
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c2d366c4edf222d909ddc5644150638a
https://doi.org/10.1152/ajplung.00530.2016
https://doi.org/10.1152/ajplung.00530.2016
Autor:
Dean Sheppard, Michael A. Thompson, Xin Ren, Austin Hsu, Agnieszka P. Looney, Valerie Fong, Mallar Bhattacharya, Rodney D. Britt, Sarah A. Wicher, Esther Wu, Y. S. Prakash, Previn Ganesan
Publikováno v:
JCI insight. 3(21)
Patients with severe, treatment-refractory asthma are at risk for death from acute exacerbations. The cytokine IL17A has been associated with airway inflammation in severe asthma, and novel therapeutic targets within this pathway are urgently needed.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f64f6040f46b40e38db8ad616602c056
https://pubmed.ncbi.nlm.nih.gov/30385725
https://pubmed.ncbi.nlm.nih.gov/30385725
Publikováno v:
Research report (Health Effects Institute). (191)
Exposure to ozone induces deleterious responses in the airways that include shortness of breath, inflammation, and bronchoconstriction. People with asthma have increased airway sensitivity to ozone and other irritants. Dr. Allison Fryer and colleague
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::7fdf51312586f11257bf6f51d899b18f
https://pubmed.ncbi.nlm.nih.gov/29659241
https://pubmed.ncbi.nlm.nih.gov/29659241
Autor:
Christina M. Pabelick, L. Manlove, Michael D. Thompson, Pavan Parikh, Elizabeth A. Stewart, Mackenzie D. Purdy, Anne A. Roesler, Rodney D. Britt, Y. S. Prakash, Sarah A. Wicher, Jovanka Ravix, Lydia D. Wheeler
Publikováno v:
The FASEB Journal. 32
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::22a7249347afd60cacd00881b1ffe589
https://doi.org/10.1096/fasebj.2018.32.1_supplement.770.10
https://doi.org/10.1096/fasebj.2018.32.1_supplement.770.10
Publikováno v:
Allergy and immunology.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::aa13eb14b688f2905d7edf14eb9d83dc
https://doi.org/10.1183/1393003.congress-2017.pa1151
https://doi.org/10.1183/1393003.congress-2017.pa1151
Autor:
Sarah A Wicher, Gustavo Arrizabalaga, Jack Sullivan, Douglas A. Pace, Maria E. Francia, Silvia N.J. Moreno
Publikováno v:
Experimental Cell Research. 317:1382-1396
The obligate intracellular parasite Toxoplasma gondii is exposed to a variety of physiological conditions while propagating in an infected organism. The mechanisms by which Toxoplasma overcomes these dramatic changes in its environment are not known.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b373e5944d0b8adb39fc8b752e35ebe2
https://doi.org/10.1016/j.yexcr.2011.03.020
https://doi.org/10.1016/j.yexcr.2011.03.020
Publikováno v:
Physiological Reports
Ozone is an atmospheric pollutant that causes lung inflammation and airway hyperresponsiveness. Ozone9s effects occur in two distinct phases that are mediated by different populations of eosinophils. In the acute phase 1 day after exposure, mature ai
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b0bb028517141c705b6cdc630c2abbf5
https://doi.org/10.14814/phy2.13538
https://doi.org/10.14814/phy2.13538
Autor:
Sarah A Wicher, Jamie Hass, DN Mcllroy, Gustavo Arrizabalaga, Nathan Bridges, Erin M. Garrison, Ben Knapp
Publikováno v:
Journal of Nanobiotechnology, Vol 10, Iss 1, p 6 (2012)
Journal of Nanobiotechnology
Journal of Nanobiotechnology
Background The design of biomimetic materials that parallel the morphology and biology of extracellular matrixes is key to the ability to grow functional tissues in vitro and to enhance the integration of biomaterial implants into existing tissues in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dbfb001c98e8b5c7f12ad09ca3b2e00c