Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Sarah A Tursi"'
Autor:
Roberto Caricchio, Stefania Gallucci, Michael H Lee, Sarah A Tursi, Lauren K Nicastro, Çagla Tükel, Benjamin L Green
Publikováno v:
Lupus Science and Medicine, Vol 8, Iss Suppl 2 (2021)
Externí odkaz:
https://doaj.org/article/30ac2195e7c44342bd9f33317a796b09
Autor:
R Paul Wilson, Sarah A Tursi, Glenn J Rapsinski, Nicole J Medeiros, Long S Le, Kevin P Kotredes, Sajan Patel, Elisabetta Liverani, Shuang Sun, Wenhan Zhu, Laurie Kilpatrick, Sebastian E Winter, Ana M Gamero, Çagla Tükel
Publikováno v:
PLoS Pathogens, Vol 15, Iss 4, p e1007745 (2019)
The mechanisms by which the gut luminal environment is disturbed by the immune system to foster pathogenic bacterial growth and survival remain incompletely understood. Here, we show that STAT2 dependent type I IFN signaling contributes to the inflam
Externí odkaz:
https://doaj.org/article/648625e4182d42e88ea88a6f56d5c0a6
Autor:
Sarah A Tursi, Ernest Y Lee, Nicole J Medeiros, Michael H Lee, Lauren K Nicastro, Bettina Buttaro, Stefania Gallucci, Ronald Paul Wilson, Gerard C L Wong, Çagla Tükel
Publikováno v:
PLoS Pathogens, Vol 13, Iss 4, p e1006315 (2017)
Bacterial biofilms are associated with numerous human infections. The predominant protein expressed in enteric biofilms is the amyloid curli, which forms highly immunogenic complexes with DNA. Infection with curli-expressing bacteria or systemic expo
Externí odkaz:
https://doaj.org/article/ab1761a0ea1e4e6b805a725f50f361e1
Autor:
Kaitlyn Grando, Lauren K. Nicastro, Sarah A. Tursi, Jaime De Anda, Ernest Y. Lee, Gerard C. L. Wong, Çağla Tükel
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 12 (2022)
The bacterial amyloid curli, produced by Enterobacteriales including Salmonella species and Escherichia coli, is implicated in the pathogenesis of several complex autoimmune diseases. Curli binds to extracellular DNA, and these complexes drive autoim
Externí odkaz:
https://doaj.org/article/87edc39e6510410cb2ecc65a785cf741
Autor:
Bettina A. Buttaro, T. Hunter, K. Malhotra, B. Henry, P. Gaddameedi, Gillian Queisser, Michael Hoffer, Sarah A. Tursi, Çagla Tükel, Y. Ishmail
Publikováno v:
Journal of Bacteriology
Mathematical models are necessary to understand how the material composition of biofilms can influence their physical properties. Here, we developed a 4D computational toolchain for the analysis of bead trajectories, which laid the groundwork for est
Autor:
Çagla Tükel, Melissa B. Palmer, Ryan Krochak, Nicole J. Medeiros, Lauren K. Nicastro, Nikole L. Watson, Elizabeth G. Hansen, Keith D. MacKenzie, Yi Zhang, Sarah A. Tursi, Aaron White, Heather L. Wilson, Amanda L. Miller, Dakoda J. Herman, Akosiererem S. Sokaribo, R. Paul Wilson, J. Alex Pasternak
Publikováno v:
PLoS Pathogens, Vol 16, Iss 7, p e1008591 (2020)
PLoS Pathogens
PLoS Pathogens
Reactive arthritis, an autoimmune disorder, occurs following gastrointestinal infection with invasive enteric pathogens, such as Salmonella enterica. Curli, an extracellular, bacterial amyloid with cross beta-sheet structure can trigger inflammatory
Autor:
William K. Cornwell, Çagla Tükel, Thomas J. Rogers, Shuang Sun, Elisabetta Liverani, Mark J. Mondrinos, Laurie E. Kilpatrick, Marla R. Wolfson, Sarah A. Tursi, Bettina A. Buttaro
Publikováno v:
FASEB J
Sepsis is a leading cause of morbidity and mortality in intensive care units. Previously, we identified Protein Kinase C-delta (PKCδ) as an important regulator of the inflammatory response in sepsis. An important issue in development of anti-inflamm
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a95eb8c4932d1984917a5b3105ffe756
https://europepmc.org/articles/PMC7568544/
https://europepmc.org/articles/PMC7568544/
Autor:
Çagla Tükel, Sarah A. Tursi, Lauren K. Nicastro, Lynne Kohler, Roberto Caricchio, Stefania Gallucci, Chelsea Corradetti, Jay Ghadiali, Paul M. Gallo, Ryan J Pachucki
Publikováno v:
Arthritis Rheumatol
Objective Infections contribute to morbidity and mortality in systemic lupus erythematosus (SLE). Uropathogenic Escherichia coli (UPEC) are known to trigger urinary tract infections (UTIs) and form biofilms, which are multicellular communities of bac
Autor:
Meghan A. Wynosky-Dolfi, B. Brett Finlay, Igor E. Brodsky, Sergei I. Grivennikov, Çagla Tükel, Kathy Q. Cai, Masahiro Yamamoto, Joris van der Heijden, Justin P. Ingram, Ting Zhang, Siddharth Balachandran, Sarah A. Tursi, Wei Guo, Chaoran Yin
Publikováno v:
The Journal of Immunology. 200:3626-3634
The cytokine IFN-γ has well-established antibacterial properties against the bacterium Salmonella enterica in phagocytes, but less is known about the effects of IFN-γ on Salmonella-infected nonphagocytic cells, such as intestinal epithelial cells (
Autor:
Lauren K. Nicastro, Çagla Tükel, Bettina A. Buttaro, Long S. Le, Vincent H. Tam, Amanda L. Miller, Sarah A. Tursi, Andrey Efimov
Publikováno v:
Journal of Bacteriology. 201
Enterobacteriaceae produce amyloid proteins called curli that are the major proteinaceous component of biofilms. Amyloids are also produced by humans and are associated with diseases such as Alzheimer's. During the multistep process of amyloid format