Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Sarah A Ngugi"'
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 15, Iss 2, p e0009016 (2021)
Burkholderia pseudomallei is the causative agent of melioidosis, which is a Gram negative, facultative intracellular bacterium. Disease is prevalent in SE Asia and in northern Australia, as well as in other tropical and subtropical regions. Recently,
Externí odkaz:
https://doaj.org/article/b64715bc53c24e6287ffe78a6e76a1c6
Autor:
Tassili A F Weehuizen, Joann L Prior, Thomas W van der Vaart, Sarah A Ngugi, Sergey A Nepogodiev, Robert A Field, Liesbeth M Kager, Cornelis van 't Veer, Alex F de Vos, W Joost Wiersinga
Publikováno v:
PLoS ONE, Vol 10, Iss 12, p e0145397 (2015)
The Gram-negative bacterium Burkholderia pseudomallei causes melioidosis and is a CDC category B bioterrorism agent. Toll-like receptor (TLR)-2 impairs host defense during pulmonary B.pseudomallei infection while TLR4 only has limited impact. We inve
Externí odkaz:
https://doaj.org/article/fd71441681d2486eaba25efa5b15a2d1
Autor:
Andrew E. Scott, Sarah A. Ngugi, Thomas R. Laws, David Corser, Claire L. Lonsdale, Riccardo V. D’Elia, Richard W. Titball, E. Diane Williamson, Timothy P. Atkins, Joann L. Prior
Publikováno v:
Journal of Immunology Research, Vol 2014 (2014)
Melioidosis is a severe infectious disease caused by Burkholderia pseudomallei. It is refractory to antibiotic treatment and there is currently no licensed vaccine. In this report we detail the construction and protective efficacy of a polysaccharide
Externí odkaz:
https://doaj.org/article/4b148131007d4b5cb25b8f4c6c672a8e
Publikováno v:
PLoS Neglected Tropical Diseases
PLoS Neglected Tropical Diseases, Vol 15, Iss 2, p e0009016 (2021)
PLoS Neglected Tropical Diseases, Vol 15, Iss 2, p e0009016 (2021)
Burkholderia pseudomallei is the causative agent of melioidosis, which is a Gram negative, facultative intracellular bacterium. Disease is prevalent in SE Asia and in northern Australia, as well as in other tropical and subtropical regions. Recently,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1a0c5fd8492e0133c08c170feb7f1e3a
https://doi.org/10.1371/journal.pntd.0009016
https://doi.org/10.1371/journal.pntd.0009016
Publikováno v:
International Journal of Experimental Pathology
Summary The marmoset model of melioidosis was used to explore whether there was any difference in the disease presentation and/or the lesion formation following inhalational challenge with one of four strains of Burkholderia pseudomallei (K96243, 102
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::24c5c07ac0014db0e3b1aec3d63b9ed1
https://doi.org/10.1111/iep.12161
https://doi.org/10.1111/iep.12161
Autor:
Mark S. Lever, Lyn M. O’Brien, Andrew Dutch, Sophie J. Smither, Lin Eastaugh, Sarah A. Ngugi, Amanda L. Phelps
Publikováno v:
Viruses
Viruses, Vol 8, Iss 7, p 185 (2016)
Viruses; Volume 8; Issue 7; Pages: 185
Viruses, Vol 8, Iss 7, p 185 (2016)
Viruses; Volume 8; Issue 7; Pages: 185
The West Africa Ebola virus (EBOV) outbreak has highlighted the need for effective disinfectants capable of reducing viral load in a range of sample types, equipment and settings. Although chlorine-based products are widely used, they can also be dam
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ad9ec99c47f9383ed6a6c1207ab3cafd
https://pubmed.ncbi.nlm.nih.gov/27527208
https://pubmed.ncbi.nlm.nih.gov/27527208
Autor:
Jackie Steward, Sophie J. Smither, Sarah A. Ngugi, Lin Eastaugh, Amanda L. Phelps, Lyn M. O’Brien, Mark S. Lever
Publikováno v:
The Journal of infectious diseases. 214(suppl 3)
Ebola virus Makona (EBOV-Makona; from the 2013-2016 West Africa outbreak) shows decreased virulence in an immune-deficient mouse model, compared with a strain from 1976. Unlike other filoviruses tested, EBOV-Makona may be slightly more virulent by th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ccbb62f01615edfcf77b12bcd84cc9ab
https://pubmed.ncbi.nlm.nih.gov/27471321
https://pubmed.ncbi.nlm.nih.gov/27471321
Autor:
Sarah A. Ngugi, Christopher M. Stead, G. Barrie Kitto, Haley Kensing, Judit M. Nagy, Thomas W. Cullen, Kate McCaul, Sachdev S. Sidhu, Barbara M. Judy, Alexandria Lipka, D. Mark Estes, Katherine A. Brown, Sarah V. Harding, George Georgiou, Mridula Rani, Brent L. Iverson, Alfredo G. Torres, Richard W. Titball, Gregory C. Whitlock, M. Stephen Trent, Omar I Qazi, Joann L. Prior, Annie J. Gnanam
Publikováno v:
Faraday Discuss.. 149:23-36
Rapid detection of the category B biothreat agents Burkholderia pseudomallei and Burkholderia mallei in acute infections is critical to ensure that appropriate treatment is administered quickly to reduce an otherwise high probability of mortality (ca
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::58df3fd8fa46872f9a83f143d795967a
https://doi.org/10.1039/c005422b
https://doi.org/10.1039/c005422b
Autor:
Katherine A. Brown, Timothy P. Atkins, Omar I Qazi, Richard W. Titball, Anne Dell, D. Mark Estes, Joann L. Prior, Valeria V. Ventura, Paul G. Hitchen, Sarah A. Ngugi, Sarah V. Harding, G. Barrie Kitto
Publikováno v:
Vaccine. 28:7551-7555
Burkholderia thailandensis is a less virulent close relative of Burkholderia pseudomallei, a CDC category B biothreat agent. We have previously shown that lipopolysaccharide (LPS) extracted from B. pseudomallei can provide protection against a lethal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a3c241640a39f5eb9ac471a6ee6286a0
https://doi.org/10.1016/j.vaccine.2010.08.058
https://doi.org/10.1016/j.vaccine.2010.08.058
Autor:
Lyn M. O’Brien, Steve G Lonsdale, Sarah A. Ngugi, Amanda L. Phelps, Lin Eastaugh, Sophie J. Smither, Simon A. Weller, Mark S. Lever, Jackie Steward
Rapid inactivation of Ebola virus (EBOV) is crucial for high-throughput testing of clinical samples in low-resource, outbreak scenarios. The EBOV inactivation efficacy of Buffer AVL (Qiagen) was tested against marmoset serum (EBOV concentration of 1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2f6fc92c095992f624bee297298835ac
https://europepmc.org/articles/PMC4572529/
https://europepmc.org/articles/PMC4572529/
