Výsledky vyhledávání - "Sarah A Ingelse"

Akademický článek

Alkaline phosphatase in pulmonary inflammation—a translational study in ventilated critically ill patients and rats

Autor: Jenny Juschten, Sarah A. Ingelse, Lieuwe D. J. Bos, Armand R. J. Girbes, Nicole P. Juffermans, Tom van der Poll, Marcus J. Schultz, Pieter Roel Tuinman, for the BASIC study investigators

Publikováno v: Intensive Care Medicine Experimental, Vol 8, Iss S1, Pp 1-14 (2020)

Abstract Background Alkaline phosphatase (AP), a dephosphorylating enzyme, is involved in various physiological processes and has been shown to have anti-inflammatory effects. Aim To determine the correlation between pulmonary AP activity and markers

Externí odkaz: https://doaj.org/article/3def5745b8fe4896996a156d0e8e6485

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Akademický článek

Current Practice of Fluid Maintenance and Replacement Therapy in Mechanically Ventilated Critically Ill Children: A European Survey

Autor: Ismail Arrahmani, Sarah A. Ingelse, Job B. M. van Woensel, Reinout A. Bem, Joris Lemson

Publikováno v: Frontiers in Pediatrics, Vol 10 (2022)

Appropriate fluid management in mechanically ventilated critically ill children remains an important challenge and topic of active discussion in pediatric intensive care medicine. An increasing number of studies show an association between a positive

Externí odkaz: https://doaj.org/article/b783e4fe852846059e77b2c90cbcc275

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Akademický článek

Antithrombin plus alpha-1 protease inhibitor does not affect coagulation and inflammation in two murine models of acute lung injury

Autor: Jenny Juschten, Sarah Anne Ingelse, Martinus Adrianus Wilhelmus Maas, Armand Roelof Johan Girbes, Nicole Petra Juffermans, Marcus Josephus Schultz, Pieter Roel Tuinman

Publikováno v: Intensive Care Medicine Experimental, Vol 7, Iss S1, Pp 1-12 (2019)

Abstract Background In acute respiratory distress syndrome (ARDS), uncontrolled production of activators of coagulation and proinflammatory mediators results in a shift from an adequate local innate immune response to hypercoagulability and inflammat

Externí odkaz: https://doaj.org/article/dfeac79b4ccb4afdb7be892ea2cae86a

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Akademický článek

Age-dependent differences in pulmonary host responses in ARDS: a prospective observational cohort study

Publikováno v: Annals of Intensive Care, Vol 9, Iss 1, Pp 1-9 (2019)

Abstract Background Results from preclinical studies suggest that age-dependent differences in host defense and the pulmonary renin–angiotensin system (RAS) are responsible for observed differences in epidemiology of acute respiratory distress synd

Externí odkaz: https://doaj.org/article/0eb053f78b0a436991dd632c9fd09910

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Akademický článek

Less Is More?—A Feasibility Study of Fluid Strategy in Critically Ill Children With Acute Respiratory Tract Infection

Autor: Sarah A. Ingelse, Vincent G. Geukers, Monique E. Dijsselhof, Joris Lemson, Reinout A. Bem, Job B. van Woensel

Publikováno v: Frontiers in Pediatrics, Vol 7 (2019)

Background: Fluid overload is common in critically ill children and is associated with adverse outcome. Therefore, restricting fluid intake may be beneficial. This study aims to study the feasibility of a randomized controlled trial (RCT) comparing a

Externí odkaz: https://doaj.org/article/1538e09ebd3c43fea06d3e628354bc8d

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Akademický článek

Fluid restriction reduces pulmonary edema in a model of acute lung injury in mechanically ventilated rats.

Autor: Sarah A Ingelse, Jenny Juschten, Martinus A W Maas, Gustavo Matute-Bello, Nicole P Juffermans, Job B M van Woensel, Reinout A Bem

Publikováno v: PLoS ONE, Vol 14, Iss 1, p e0210172 (2019)

Experimental acute lung injury models are often used to increase our knowledge on the acute respiratory distress syndrome (ARDS), however, existing animal models often do not take into account the impact of specific fluid strategies on the developmen

Externí odkaz: https://doaj.org/article/62b8c4ee96c34567b41dc5c737827c8f

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Early restrictive fluid resuscitation has no clinical advantage in experimental severe pediatric acute respiratory distress syndrome

Autor: Reinout A. Bem, Job B. M. van Woensel, Joris Lemson, Marloes M. Ijland, Lex M. van Loon, Sarah A. Ingelse

Publikováno v: American Journal of Physiology : Lung Cellular and Molecular Physiology, 320, 6, pp. L1126-l1136
American journal of physiology. Lung cellular and molecular physiology, 320(6), L1126-L1136. American Physiological Society
American Journal of Physiology : Lung Cellular and Molecular Physiology, 320, L1126-l1136

Contains fulltext : 245043.pdf (Publisher’s version ) (Closed access) Intravenous fluids are widely used to treat circulatory deterioration in pediatric acute respiratory distress syndrome (PARDS). However, the accumulation of fluids in the first d

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::306840a4df041aa060f77534f1edfca7
http://www.scopus.com/inward/record.url?scp=85108742269&partnerID=8YFLogxK

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Akademický článek

Pediatric acute respiratory distress syndrome: fluid management in the PICU

Autor: Sarah A Ingelse, Roelie M Wösten - van Asperen, Joris eLemson, Joost G Daams, Reinout A Bem, Job BM van Woensel

Publikováno v: Frontiers in Pediatrics, Vol 4 (2016)

The administration of an appropriate volume of intravenous fluids, while avoiding fluid overload, is a major challenge in the pediatric intensive care unit. Despite our efforts, fluid overload is a very common clinical observation in critically ill c

Externí odkaz: https://doaj.org/article/8126ad58e7c34c32bd63ea62a5b68c55

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Alkaline phosphatase in pulmonary inflammation—a translational study in ventilated critically ill patients and rats

Autor: Nicole P. Juffermans, Armand R. J. Girbes, Tom van der Poll, Pieter R. Tuinman, Jenny Juschten, Sarah A. Ingelse, Lieuwe D. J. Bos, Marcus J. Schultz

Publikováno v: Intensive Care Medicine Experimental, 8(Suppl 1):46. Springer Science + Business Media
Intensive Care Medicine Experimental
Intensive Care Medicine Experimental, 8:46. Springer Science + Business Media
BASIC study investigators 2020, ' Alkaline phosphatase in pulmonary inflammation—a translational study in ventilated critically ill patients and rats ', Intensive Care Medicine Experimental, vol. 8, 46 . https://doi.org/10.1186/s40635-020-00335-x
Intensive Care Medicine Experimental, Vol 8, Iss S1, Pp 1-14 (2020)

Background Alkaline phosphatase (AP), a dephosphorylating enzyme, is involved in various physiological processes and has been shown to have anti-inflammatory effects. Aim To determine the correlation between pulmonary AP activity and markers of infla

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ef2353f108db5a8817da1ee4fd231a63
https://doi.org/10.1186/s40635-020-00335-x

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Lung ultrasound scoring in invasive mechanically ventilated children with severe bronchiolitis

Autor: Job B. M. van Woensel, Marcus J. Schultz, Reinout A. Bem, Mariam Almakdase, Luigi Pisani, Marloes H. A. Westdorp, Sarah A. Ingelse

Publikováno v: Pediatric pulmonology, 55(10), 2799-2805. Wiley-Liss Inc.

Objective: Lung ultrasound (LUS) is an emerging tool that may be used in the diagnosis and follow-up of children with viral bronchiolitis. In this study, we describe LUS abnormalities in children receiving invasive mechanical ventilation (IMV) for se

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::635b34ebd15bb60209a05df0963a67d0
https://pubmed.ncbi.nlm.nih.gov/32696620

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