Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Sarah A Greaves"'
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
Pulmonary sarcoidosis and chronic beryllium disease (CBD) are inflammatory granulomatous lung diseases defined by the presence of non-caseating granulomas in the lung. CBD results from beryllium exposure in the workplace, while the cause of sarcoidos
Externí odkaz:
https://doaj.org/article/bbb6692245524e55837853f11acf3edf
Autor:
Roberta Pelanda, Sarah A. Greaves, Thiago Alves da Costa, Lena M. Cedrone, Margaret L. Campbell, Raul M. Torres
Publikováno v:
Immunol Rev
The random recombination of immunoglobulin V(D)J gene segments produces unique IgM antibodies that serve as the antigen receptor for each developing B cell. Hence, the newly formed B cell repertoire is comprised of a variety of specificities that dis
Publikováno v:
Frontiers in Immunology, Vol 9 (2018)
Externí odkaz:
https://doaj.org/article/c2bb3c5107c2456695f98cff477f27ae
Publikováno v:
Frontiers in Immunology, Vol 9 (2018)
Newly generated bone marrow B cells are positively selected into the peripheral lymphoid tissue only when they express a B cell receptor (BCR) that is nonautoreactive or one that binds self-antigen with only minimal avidity. This positive selection p
Externí odkaz:
https://doaj.org/article/45717056a3c94f86b6811778358ae5bb
Autor:
Angela M. Mitchell, Shaodong Dai, Michael T. Falta, Lisa A. Maier, Shaikh M. Atif, Lan Chen, Andrew P. Fontenot, Alex N. Tinega, Sarah A. Greaves, Johan Grunewald, Clemencia Pinilla, Yang Wang, Radleigh Santos, Douglas G. Mack, Avinash Ravindran
Publikováno v:
The Journal of experimental medicine. 218(10)
Löfgren’s syndrome (LS) is an acute form of sarcoidosis characterized by a genetic association with HLA-DRB1*03 (HLA-DR3) and an accumulation of CD4+ T cells of unknown specificity in the bronchoalveolar lavage (BAL). Here, we screened related LS-
Autor:
Sarah A Greaves, Michael Falta, Radleigh Santos, Clemencia Pinilla, Johan Grunewald, Andrew Fontenot
Publikováno v:
The Journal of Immunology. 204:224.26-224.26
Sarcoidosis is an inflammatory granulomatous disease that primarily affects the lung. It has a worldwide distribution and affects individuals of all ages. Despite the prevalence of the disease, the cause of sarcoidosis remains unknown. Evidence sugge
Autor:
Sarah A Greaves, Angela Mitchell, Michael Falta, Radleigh Santos, Clemencia A Pinilla, Andrew P Fontenot
Publikováno v:
The Journal of Immunology. 202:182.57-182.57
Sarcoidosis is an inflammatory granulomatous disease that primarily affects the lung. It has a worldwide distribution and affects individuals of all ages, races and both sexes. Despite the prevalence of the disease and continued investigation, the ca
Publikováno v:
The Journal of Immunology. 198:202.6-202.6
B cell selection mechanisms in the bone marrow control the nature of the primary B cell repertoire, generating diverse specificities while reducing autoreactivity. Our studies aim to characterize the mechanisms that drive the positive selection of im
Autor:
Sarah A. Greaves, Lenka S. Teodorovic, Sarah L. Rowland, Chiara Babolin, Roberta Pelanda, Raul M. Torres, David P. Baldwin
Publikováno v:
Proceedings of the National Academy of Sciences. 111
Newly generated immature B cells are selected to enter the peripheral mature B-cell pool only if they do not bind (or bind limited amount of) self-antigen. We previously suggested that this selection relies on basal extracellular signal-regulated kin
Publikováno v:
Spectrochimica Acta Part A: Molecular Spectroscopy. 50:857-873
The Raman and IR spectra of 1,2-diaminobenzene and 4,5-dimethyl-1,2-diaminobenzene are reported and assignments of fundamental modes proposed. The surface-enhanced Raman spectra (SERS) of catechol, 1,2-diaminobenzene and 4,5-dimethyl-1,2-diaminobenze