Zobrazeno 1 - 10
of 35
pro vyhledávání: '"Sarah A Comerford"'
Autor:
Joseph A Garcia, Rui Chen, Min Xu, Sarah A Comerford, Robert E Hammer, Shelby D Melton, Linda A Feagins
Publikováno v:
PLoS ONE, Vol 18, Iss 3, p e0282223 (2023)
The microenvironment of solid tumors is characterized by oxygen and glucose deprivation. Acss2/HIF-2 signaling coordinates essential genetic regulators including acetate-dependent acetyl CoA synthetase 2 (Acss2), Creb binding protein (Cbp), Sirtuin 1
Externí odkaz:
https://doaj.org/article/21dcbf5e7af9419d9861f6c9ebcf5d72
Publikováno v:
PLoS Genetics, Vol 19, Iss 1, p e1010595 (2023)
Defective ribosome biogenesis (RiBi) underlies a group of clinically diverse human diseases collectively known as the ribosomopathies, core manifestations of which include cytopenias and developmental abnormalities that are believed to stem primarily
Externí odkaz:
https://doaj.org/article/1b21ea99c6e74ce281bd9d329146aa8d
Publikováno v:
PLoS ONE, Vol 14, Iss 11, p e0225105 (2019)
The response to environmental stresses by eukaryotic organisms includes activation of protective biological mechanisms, orchestrated in part by transcriptional regulators. The tri-member Hypoxia Inducible Factor (HIF) family of DNA-binding transcript
Externí odkaz:
https://doaj.org/article/bcb03d18100b4e9988d8eaa09ebab5f7
Autor:
Shruthy Suresh, Deniz Durakoglugil, Xiaorong Zhou, Bokai Zhu, Sarah A Comerford, Chao Xing, Xian-Jin Xie, Brian York, Kathryn A O'Donnell
Publikováno v:
PLoS Genetics, Vol 14, Iss 4, p e1007344 (2018)
[This corrects the article DOI: 10.1371/journal.pgen.1006650.].
Externí odkaz:
https://doaj.org/article/fe423a4335a346e598e1bab67c0de77b
Autor:
Shruthy Suresh, Deniz Durakoglugil, Xiaorong Zhou, Bokai Zhu, Sarah A Comerford, Chao Xing, Xian-Jin Xie, Brian York, Kathryn A O'Donnell
Publikováno v:
PLoS Genetics, Vol 13, Iss 3, p e1006650 (2017)
Hepatocellular carcinoma (HCC) is the fifth most common solid tumor in the world and the third leading cause of cancer-associated deaths. A Sleeping Beauty-mediated transposon mutagenesis screen previously identified mutations that cooperate with MYC
Externí odkaz:
https://doaj.org/article/deb99dc4a1ec4049b3b9f8f4e0ad7a25
Autor:
Philippe H. Kobeissy, Minh Q. Nguyen, Robert E. Hammer, Min Xu, Joseph A. Garcia, Sarah A. Comerford, Trent Garcia, Jason S. Nagati
Publikováno v:
The Journal of Biological Chemistry
Besides contributing to anabolism, cellular metabolites serve as substrates or cofactors for enzymes and may also have signaling functions. Given these roles, multiple control mechanisms likely ensure fidelity of metabolite-generating enzymes. Acetat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e1b245e12bda11be33da72164d57a661
https://doi.org/10.1016/j.jbc.2021.101037
https://doi.org/10.1016/j.jbc.2021.101037
Autor:
Robert E. Hammer, Trent Garcia, Jason S. Nagati, Min Xu, Sarah A. Comerford, Joseph A. Garcia
Publikováno v:
PLoS ONE
PLoS ONE, Vol 14, Iss 11, p e0225105 (2019)
PLoS ONE, Vol 14, Iss 11, p e0225105 (2019)
The response to environmental stresses by eukaryotic organisms includes activation of protective biological mechanisms, orchestrated in part by transcriptional regulators. The tri-member Hypoxia Inducible Factor (HIF) family of DNA-binding transcript
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::578b42ea8b1a6e279f98395729e46011
https://pubmed.ncbi.nlm.nih.gov/31725783
https://pubmed.ncbi.nlm.nih.gov/31725783
Autor:
Sarah A. Comerford, Alejandro D’Brot, John M. Abrams, Paula Kurtz, Wan Jin Lu, Dinesh Rakheja, James F. Amatruda, Amanda E. Jones, John V. Moran, Kenneth S. Chen, Annika Wylie, Robert E. Hammer
Publikováno v:
Genes & Development. 30:64-77
Throughout the animal kingdom, p53 genes govern stress response networks by specifying adaptive transcriptional responses. The human member of this gene family is mutated in most cancers, but precisely how p53 functions to mediate tumor suppression i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5a2e7818a88932ff7a4e51f57827f000
https://doi.org/10.1101/gad.266098.115
https://doi.org/10.1101/gad.266098.115
Autor:
Kathryn A. O'Donnell, Chao Xing, Shruthy Suresh, Brian York, Sarah A. Comerford, Xian Jin Xie, Xiaorong Zhou, Deniz Durakoglugil, Bokai Zhu
Publikováno v:
PLoS Genetics, Vol 14, Iss 4, p e1007344 (2018)
PLoS Genetics
PLoS Genetics
Hepatocellular carcinoma (HCC) is the fifth most common solid tumor in the world and the third leading cause of cancer-associated deaths. A Sleeping Beauty-mediated transposon mutagenesis screen previously identified mutations that cooperate with MYC
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0fccd7505b529c99d3cf95ee94147f90
http://europepmc.org/articles/PMC5894952?pdf=render
http://europepmc.org/articles/PMC5894952?pdf=render
Autor:
Kathryn A. O'Donnell, Xiaorong Zhou, Shruthy Suresh, Chao Xing, Xian Jin Xie, Deniz Durakoglugil, Bokai Zhu, Sarah A. Comerford, Brian York
Publikováno v:
PLoS Genetics, Vol 13, Iss 3, p e1006650 (2017)
Hepatocellular carcinoma (HCC) is the fifth most common solid tumor in the world and the third leading cause of cancer-associated deaths. A Sleeping Beauty-mediated transposon mutagenesis screen previously identified mutations that cooperate with MYC
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2afd875eeb6fc4adbc970ae834262540
http://europepmc.org/articles/PMC5362238?pdf=render
http://europepmc.org/articles/PMC5362238?pdf=render