Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Sarah A, Michaud"'
Autor:
Sarah A. Michaud, Helena Pětrošová, Nicholas J. Sinclair, Andrea L. Kinnear, Angela M. Jackson, Jamie C. McGuire, Darryl B. Hardie, Pallab Bhowmick, Milan Ganguly, Ann M. Flenniken, Lauryl M. J. Nutter, Colin McKerlie, Derek Smith, Yassene Mohammed, David Schibli, Albert Sickmann, Christoph H. Borchers
Publikováno v:
Communications Biology, Vol 7, Iss 1, Pp 1-12 (2024)
Abstract Mouse is the mammalian model of choice to study human health and disease due to its size, ease of breeding and the natural occurrence of conditions mimicking human pathology. Here we design and validate multiple reaction monitoring mass spec
Externí odkaz:
https://doaj.org/article/2609ea2007ea4af7ba418d2b5f7ec603
Autor:
Michel Allard, Emmanuel L’Hérault, Sarah Aubé-Michaud, Andrée-Sylvie Carbonneau, Valérie Mathon-Dufour, Arianne B.-St-Amour, Sarah Gauthier
Publikováno v:
Arctic Science, Vol 9, Iss 3, Pp 657-677 (2023)
To support climate change adaptation in the communities of Nunavik, an innovative multitechnique approach to map permafrost conditions and assess risks of geohazards at the community-scale level was applied. Four maps were produced for each community
Externí odkaz:
https://doaj.org/article/bc30831874ad4dac841fbf21d57b7ec2
Autor:
Yassene Mohammed, Sarah A. Michaud, Helena Pětrošová, Juncong Yang, Milan Ganguly, David Schibli, Ann M. Flenniken, Lauryl M. J. Nutter, Hibret A. Adissu, K. C. Kent Lloyd, Colin McKerlie, Christoph H. Borchers
Publikováno v:
npj Systems Biology and Applications, Vol 7, Iss 1, Pp 1-23 (2021)
Abstract We proteotyped blood plasma from 30 mouse knockout strains and corresponding wild-type mice from the International Mouse Phenotyping Consortium. We used targeted proteomics with internal standards to quantify 375 proteins in 218 samples. Our
Externí odkaz:
https://doaj.org/article/72bd932c9079468a9baf2be34f40d25f
Autor:
Sarah A. Michaud, Angela M. Jackson, Christoph H. Borchers, Derek Smith, Ann M Flenniken, Nicholas J. Sinclair, Colin McKerlie, Lauryl M. J. Nutter, Milan Ganguly, David Schibli, Helena Pětrošová, Jamie C McGuire
Publikováno v:
Journal of Proteome Research. 20:305-316
We investigated the effect of homogenization strategy and protein precipitation on downstream protein quantitation using multiple reaction monitoring mass spectrometry (MRM-MS). Our objective was to develop a workflow capable of processing disparate
Autor:
Abbey E, Wilson, Sarah A, Michaud, Angela M, Jackson, Gordon, Stenhouse, Cameron J R, McClelland, Nicholas C, Coops, David M, Janz
Publikováno v:
Conservation Physiology
Monitoring the reproductive characteristics of a species can complement existing conservation strategies by understanding the mechanisms underlying demography. However, methodology to determine important aspects of female reproductive biology is ofte
Publikováno v:
Bioinformatics, 37(13), 1900-1908. OXFORD UNIV PRESS
MotivationLaboratory mouse is the most used animal model in biological research, largely due to its high conserved synteny with human. Researchers use mice to answer various questions ranging from determining a pathological effect of knocked out/in g
Autor:
Hibret A. Adissu, Sarah A. Michaud, Helena Pětrošová, Christoph H. Borchers, Juncong Yang, Colin McKerlie, Milan Ganguly, Yassene Mohammed, Ann M Flenniken, David Schibli, Lauryl M. J. Nutter, Kevin C K Lloyd
Publikováno v:
NPJ Systems Biology and Applications
npj Systems Biology and Applications, 7(1). NATURE RESEARCH
npj Systems Biology and Applications, Vol 7, Iss 1, Pp 1-23 (2021)
NPJ systems biology and applications, vol 7, iss 1
npj Systems Biology and Applications, 7(1). NATURE RESEARCH
npj Systems Biology and Applications, Vol 7, Iss 1, Pp 1-23 (2021)
NPJ systems biology and applications, vol 7, iss 1
We proteotyped blood plasma from 30 mouse knockout strains and corresponding wild-type mice from the International Mouse Phenotyping Consortium. We used targeted proteomics with internal standards to quantify 375 proteins in 218 samples. Our results
Autor:
Sarah A. Michaud, Christoph H. Borchers, Julia Tilburg, Henri H. Versteeg, Yassene Mohammed, Bart J.M. van Vlijmen, Chrissta X. Maracle
Publikováno v:
Thrombosis and Haemostasis, 120(3), 423-436. GEORG THIEME VERLAG KG
The plasma compartment of the blood holds important information on the risk to develop cardiovascular diseases such as venous thrombosis (VT). Mass spectrometry-based targeted proteomics with internal standards quantifies proteins in multiplex allowi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9b4bb63a1a4fe8590b2eb9c6bc6eb806
https://hdl.handle.net/1887/3182306
https://hdl.handle.net/1887/3182306
Autor:
Sarah A. Michaud, Gordon B. Stenhouse, Angela M. Jackson, David M. Janz, Abbey E. Wilson, Nicholas C. Coops
Publikováno v:
Conservation Physiology
Large carnivores play critical roles in the maintenance and function of natural ecosystems; however, the populations of many of these species are in decline across the globe. Therefore, there is an urgent need to develop novel techniques that can be
Autor:
Sarah A. Michaud, Nicholas J. Sinclair, Darryl B. Hardie, Christoph H. Borchers, Juncong Yang, Andrew J. Percy, Adam J. Pistawka, André LeBlanc, Derek Smith, Jillaine I. Proudfoot
Publikováno v:
Journal of proteome research. 16(7)
When quantifying endogenous plasma proteins for fundamental and biomedical research - as well as for clinical applications - precise, reproducible, and robust assays are required. Targeted detection of peptides in a bottom-up strategy is the most com