Zobrazeno 1 - 10
of 33
pro vyhledávání: '"Sarah Tonack"'
Autor:
Kaare V. Grunddal, Sarah Tonack, Kristoffer L. Egerod, Jonathan James Thompson, Natalia Petersen, Maja S. Engelstoft, Constance Vagne, Céline Keime, Gérard Gradwohl, Stefan Offermanns, Thue W. Schwartz
Publikováno v:
Molecular Metabolism, Vol 51, Iss , Pp 101231- (2021)
Objective: GPR64/ADGRG2 is an orphan Adhesion G protein-coupled receptor (ADGR) known to be mainly expressed in the parathyroid gland and epididymis. This investigation aimed to delineate the cellular expression of GPR64 throughout the body with focu
Externí odkaz:
https://doaj.org/article/7ee8630e8aa2483798aecb86304f3a04
Autor:
Akiko Nakayama, Julián Albarrán-Juárez, Guozheng Liang, Kenneth Anthony Roquid, András Iring, Sarah Tonack, Min Chen, Oliver J. Müller, Lee S. Weinstein, Stefan Offermanns
Publikováno v:
JCI Insight, Vol 5, Iss 23 (2020)
Atherosclerosis develops preferentially in areas of the arterial system, in which blood flow is disturbed. Exposure of endothelial cells to disturbed flow has been shown to induce inflammatory signaling, including NF-κB activation, which leads to th
Externí odkaz:
https://doaj.org/article/c1ebda9a5f75409cbfaf0b5ba83c0cbb
Autor:
Calin-Petru Manta, Thomas Leibing, Mirco Friedrich, Hendrik Nolte, Monica Adrian, Kai Schledzewski, Jessica Krzistetzko, Christof Kirkamm, Christian David Schmid, Yannick Xi, Ana Stojanovic, Sarah Tonack, Carolina de la Torre, Seddik Hammad, Stefan Offermanns, Marcus Krüger, Adelheid Cerwenka, Michael Platten, Sergij Goerdt, Cyrill Géraud
Publikováno v:
Circulation. 146(23)
BackgroundScavenger receptors (SR) Stabilin-1 (Stab1) and Stabilin-2 (Stab2) are preferentially expressed by liver sinusoidal endothelial cells. They mediate the clearance of circulating plasma molecules controlling distant organ homeostasis. Studies
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::af6d3af1512994cfb03b54b9e7842f62
https://pubmed.ncbi.nlm.nih.gov/36325910
https://pubmed.ncbi.nlm.nih.gov/36325910
Autor:
András Iring, Oliver J. Müller, Akiko Nakayama, Guozheng Liang, Julián Albarrán-Juárez, Min Chen, Sarah Tonack, Stefan Offermanns, Lee S. Weinstein, Kenneth Anthony Roquid
Publikováno v:
JCI Insight, Vol 5, Iss 23 (2020)
JCI Insight
JCI Insight
Atherosclerosis develops preferentially in areas of the arterial system, in which blood flow is disturbed. Exposure of endothelial cells to disturbed flow has been shown to induce inflammatory signaling, including NF-κB activation, which leads to th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2dbef3830c5b8fe40fb91f3a8c5a1bde
https://doaj.org/article/c1ebda9a5f75409cbfaf0b5ba83c0cbb
https://doaj.org/article/c1ebda9a5f75409cbfaf0b5ba83c0cbb
Autor:
Julián Albarrán-Juárez, Kerstin Troidl, Thomas Schmitz-Rixen, Wolfgang Schaper, Sarah Tonack, Christian Troidl, G. Jung, Benjamin Matuschke, Wilma Schierling, Silvia Fischer, Thomas Hammerschick, Klaus T. Preissner, Marcus Krüger
Publikováno v:
Troidl, K, Hammerschick, T, Albarran-Juarez, J, Jung, G, Schierling, W, Tonack, S, Krüger, M, Matuschke, B, Troidl, C, Schaper, W, Schmitz-Rixen, T, Preissner, K T & Fischer, S 2020, ' Shear Stress-Induced miR-143-3p in Collateral Arteries Contributes to Outward Vessel Growth by Targeting Collagen V-α2 ', Arteriosclerosis, Thrombosis, and Vascular Biology, vol. 40, no. 5, pp. e126-e137 . https://doi.org/10.1161/ATVBAHA.120.313316
Objective: Arteriogenesis, describing the process of collateral artery growth, is activated by fluid shear stress (FSS). Since this vascular mechanotransduction may involve microRNAs (miRNAs), we investigated the FSS-induced expression of vascular ce
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f39c356df84f08c7b5fba7c8673b4801
https://pubmed.ncbi.nlm.nih.gov/32188276
https://pubmed.ncbi.nlm.nih.gov/32188276
Autor:
Sarah Tonack, Wencai Zhao, Stefan Günther, Harmandeep Kaur, Nadja Mößlein, Jorge Carvalho, Ramesh Chennupati, Michael Kurz, Nina Wettschureck, Moritz Bünemann, Rui Li, Stefan Offermanns
Publikováno v:
Circulation. 141(14)
Background: G protein–coupled receptors are important regulators of contractility and differentiation in vascular smooth muscle cells (SMCs), but the specific function of SMC-expressed orphan G protein–coupled receptor class C group 5 member B (G
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0219cc3993067f87ef1532029af17509
https://pubmed.ncbi.nlm.nih.gov/31941358
https://pubmed.ncbi.nlm.nih.gov/31941358
Autor:
Sarah Tonack, Thue W. Schwartz, Natalia Petersen, Céline Keime, Constance Vagne, Gérard Gradwohl, Jonathan James Thompson, Maja S. Engelstoft, Kristoffer L. Egerod, Stefan Offermanns, Kaare V. Grunddal
Publikováno v:
V. Grunddal, K, Tonack, S, Egerod, K L, Thompson, J J, Petersen, N, Engelstoft, M S, Vagne, C, Keinse, C, Gradwohl, G, Offermanns, S & Schwartz, T W 2021, ' Adhesion receptor ADGRG2/GPR64 is in the GI-tract selectively expressed in mature intestinal tuft cells ', Molecular Metabolism, vol. 51, 101231 . https://doi.org/10.1016/j.molmet.2021.101231
Molecular metabolism
Molecular metabolism, 2021, 51, ⟨10.1016/j.molmet.2021.101231⟩
Molecular Metabolism, Vol 51, Iss, Pp 101231-(2021)
Molecular metabolism
Molecular metabolism, 2021, 51, ⟨10.1016/j.molmet.2021.101231⟩
Molecular Metabolism, Vol 51, Iss, Pp 101231-(2021)
Objective: GPR64/ADGRG2 is an orphan Adhesion G protein-coupled receptor (ADGR) known to be mainly expressed in the parathyroid gland and epididymis. This investigation aimed to delineate the cellular expression of GPR64 throughout the body with focu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::82dc901ce96c3307e57d9fc46b762068
https://doi.org/10.1016/j.molmet.2021.101231
https://doi.org/10.1016/j.molmet.2021.101231
Shear stress-induced endothelial adrenomedullin signaling regulates vascular tone and blood pressure
Autor:
Akiko Nakayama, Stefan Offermanns, Min Chen, Péter T. Dancs, Stefan Günther, Sarah Tonack, Lee S. Weinstein, András Iring, Carsten Künne, Mauro Siragusa, Nina Wettschureck, Johannes Graumann, Shengpeng Wang, Young-June Jin, Ingrid Fleming, Alfredo Martínez, Julián Albarrán-Juárez, Anna M. Sokol
Publikováno v:
RIUR. Repositorio Institucional de la Universidad de La Rioja
instname
instname
Hypertension is a primary risk factor for cardiovascular diseases including myocardial infarction and stroke. Major determinants of blood pressure are vasodilatory factors such as nitric oxide (NO) released from the endothelium under the influence of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b566382e3c7db5bcb663fd294714e972
https://investigacion.unirioja.es/documentos/5d31790029995210563849ef
https://investigacion.unirioja.es/documentos/5d31790029995210563849ef
Autor:
Joachim C. Burbiel, Kerstin Troidl, Jon O. Lundberg, Harmandeep Kaur, Stefan Offermanns, Julián Albarrán Juárez, András Iring, Nina Wettschureck, Shengpeng Wang, Sarah Tonack, Boris Strilic, Ingrid Fleming, Christa E. Müller
Publikováno v:
Wang, S, Iring, A, Strilic, B, Juárez, J A, Kaur, H, Troidl, K, Tonack, S, Burbiel, J C, Müller, C E, Fleming, I, Lundberg, J O, Wettschureck, N & Offermanns, S 2015, ' P2Y2 and Gq/G11 control blood pressure by mediating endothelial mechanotransduction ' J. Clin. Invest. . https://doi.org/10.1172/jci81067
Elevated blood pressure is a key risk factor for developing cardiovascular diseases. Blood pressure is largely determined by vasodilatory mediators, such as nitric oxide (NO), that are released from the endothelium in response to fluid shear stress e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::27eb3acaa39b0f81b08db54e56fadffc
https://doi.org/10.1172/jci81067
https://doi.org/10.1172/jci81067
Autor:
Helmut Friess, Sarah Tonack, Eithne Costello, Christoph W. Michalski, Victoria Shaw, John P. Neoptolemos, Neil R. Kitteringham, William Greenhalf, Rosalind E. Jenkins, Victoria Elliott, Claire Jenkinson, Trevor Cox
Publikováno v:
British Journal of Cancer
Background: The aims of our study were to identify serum biomarkers that distinguish pancreatic cancer (pancreatic ductal adenocarcinoma, PDAC) patients from benign pancreatic disease patients and healthy subjects, and to assess the effects of jaundi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a5846f17a7dd5f52a26ab6c9533ae278
https://doi.org/10.1038/bjc.2013.150
https://doi.org/10.1038/bjc.2013.150